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6NK6
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BU of 6nk6 by Molmil
Electron Cryo-Microscopy Of Chikungunya VLP in complex with mouse Mxra8 receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, E1 glycoprotein, ...
Authors:Basore, K, Kim, A.S, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-01-04
Release date:2019-05-22
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.06 Å)
Cite:Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor.
Cell, 177, 2019
5MEN
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BU of 5men by Molmil
Human Leukocyte Antigen A02 presenting ILAKFLHWL, in complex with cognate T-Cell Receptor
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Lloyd, A, Crowther, M, Cole, D.K, Sewell, A.K.
Deposit date:2016-11-16
Release date:2016-12-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.
J. Biol. Chem., 292, 2017
7TY0
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BU of 7ty0 by Molmil
Nipah Virus attachment (G) glycoprotein ectodomain in complex with nAH1.3 neutralizing antibody Fab fragment (local refinement of the stalk region)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wang, Z.Q, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2022-02-10
Release date:2022-03-09
Last modified:2022-04-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Architecture and antigenicity of the Nipah virus attachment glycoprotein.
Science, 375, 2022
7TJ8
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BU of 7tj8 by Molmil
Cryo-EM structure of the human Nax channel in complex with beta3 solved in nanodiscs
Descriptor: (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Noland, C.L, Kschonsak, M, Ciferri, C, Payandeh, J.
Deposit date:2022-01-14
Release date:2022-03-30
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure-guided unlocking of Na X reveals a non-selective tetrodotoxin-sensitive cation channel.
Nat Commun, 13, 2022
7TJ9
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BU of 7tj9 by Molmil
Cryo-EM structure of the human Nax channel in complex with beta3 solved in GDN
Descriptor: (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Noland, C.L, Kschonsak, M, Ciferri, C, Payandeh, J.
Deposit date:2022-01-14
Release date:2022-03-30
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure-guided unlocking of Na X reveals a non-selective tetrodotoxin-sensitive cation channel.
Nat Commun, 13, 2022
6NRW
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BU of 6nrw by Molmil
Crystal structure of Dpr1 IG1 bound to DIP-eta IG1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Cheng, S, Park, Y.J, Kurleto, J.D, Ozkan, E.
Deposit date:2019-01-24
Release date:2019-02-06
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila.
Elife, 8, 2019
5MP3
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BU of 5mp3 by Molmil
Crystal structure of DC8E8 Fab in the complex with a 30-mer tau peptide at pH 6.5
Descriptor: ENSMUSG00000076577 protein, Igh protein, Microtubule-associated protein
Authors:Skrabana, R, Novak, M, Cehlar, O, Kontsekova, E.
Deposit date:2016-12-15
Release date:2018-05-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structure of DC8E8 Fab in the complex with a 30-mer tau peptide at pH 6.5
To be published
6XDS
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BU of 6xds by Molmil
Crystal structure of MBP-TREM2 Ig domain fusion with fragment, 2-((4-bromophenyl)amino)ethan-1-ol
Descriptor: 2-[(4-bromophenyl)amino]ethan-1-ol, DIMETHYL SULFOXIDE, Sugar ABC transporter substrate-binding protein,Triggering receptor expressed on myeloid cells 2, ...
Authors:Su, H.P.
Deposit date:2020-06-11
Release date:2021-02-17
Method:X-RAY DIFFRACTION (1.466 Å)
Cite:Development of a robust crystallization platform for immune receptor TREM2 using a crystallization chaperone strategy.
Protein Expr.Purif., 179, 2021
6YJP
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BU of 6yjp by Molmil
Crystal structure of a complex between glycosylated NKp30 and its deglycosylated tumour ligand B7-H6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Natural cytotoxicity triggering receptor 3, Natural cytotoxicity triggering receptor 3 ligand 1
Authors:Skalova, T, Dohnalek, J, Skorepa, O, Kalouskova, B, Pazicky, S, Blaha, J, Vanek, O.
Deposit date:2020-04-04
Release date:2020-07-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Natural Killer Cell Activation Receptor NKp30 Oligomerization Depends on Its N -Glycosylation.
Cancers (Basel), 12, 2020
5MTL
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BU of 5mtl by Molmil
Crystal structure of an amyloidogenic light chain
Descriptor: light chain dimer,IGL@ protein,IGL@ protein
Authors:Oberti, L, Rognoni, P, Russo, R, Bacarizo, J, Bolognesi, M, Ricagno, S.
Deposit date:2017-01-10
Release date:2017-12-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Sci Rep, 7, 2017
7UMG
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BU of 7umg by Molmil
Crystal structure of human CD8aa-MR1-Ac-6-FP complex
Descriptor: Beta-2-microglobulin, CHLORIDE ION, Major histocompatibility complex class I-related gene protein, ...
Authors:Awad, W, Rossjohn, J.
Deposit date:2022-04-06
Release date:2022-08-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:CD8 coreceptor engagement of MR1 enhances antigen responsiveness by human MAIT and other MR1-reactive T cells.
J.Exp.Med., 219, 2022
5NHT
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BU of 5nht by Molmil
human 199.54-16 TCR in complex with Melan-A/MART-1 (26-35) peptide and HLA-A2
Descriptor: Beta-2-microglobulin, CHLORIDE ION, HLA class I histocompatibility antigen, ...
Authors:Exertier, C, Reiser, J.-B, Lantez, V, Chouquet, A, Bonneville, M, Saulquin, X, Housset, D.
Deposit date:2017-03-22
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:human 199.54-16 TCR in complex with Melan-A/MART-1 (26-35) peptide and HLA-A2
To Be Published
7VXZ
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BU of 7vxz by Molmil
Coxsackievirus B3 at pH7.4 (VP3-234Q) incubation with coxsackievirus and adenovirus receptor for 20min
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Wang, Q.L, Liu, C.C.
Deposit date:2021-11-13
Release date:2022-01-19
Last modified:2022-08-03
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
6XEY
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BU of 6xey by Molmil
Cryo-EM structure of the SARS-CoV-2 spike glycoprotein bound to Fab 2-4
Descriptor: 2-4 Heavy Chain, 2-4 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rapp, M, Shapiro, L, Ho, D.D.
Deposit date:2020-06-14
Release date:2020-07-22
Last modified:2021-01-27
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike.
Nature, 584, 2020
5NQK
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BU of 5nqk by Molmil
human 199.16 TCR in complex with Melan-A/MART-1 (26-35) peptide and HLA-A2
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
Authors:Exertier, C, Reiser, J.-B, Lantez, V, Chouquet, A, Bonneville, M, Saulquin, X, Housset, D.
Deposit date:2017-04-20
Release date:2018-05-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:human 199.16 TCR in complex with Melan-A/MART-1 (26-35) peptide and HLA-A2
To Be Published
4BFI
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BU of 4bfi by Molmil
Structure of the complex of the extracellular portions of mouse CD200R and mouse CD200
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CELL SURFACE GLYCOPROTEIN CD200 RECEPTOR 1, ...
Authors:Hatherley, D, Lea, S.M, Johnson, S, Barclay, A.N.
Deposit date:2013-03-19
Release date:2013-05-01
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:Structures of Cd200/Cd200 Receptor Family and Implications for Topology, Regulation, and Evolution
Structure, 21, 2013
3ZL4
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BU of 3zl4 by Molmil
Antibody structural organization: Role of kappa - lambda chain constant domain switch in catalytic functionality
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, A17 ANTIBODY FAB FRAGMENT HEAVY CHAIN, A17 ANTIBODY FAB FRAGMENT LAMBDA LIGHT CHAIN
Authors:Chatziefthimiou, S.D, Ponomarenko, N.A, Kurkova, I.N, Smirnov, A.V, Smirnov, I.V, Lamzin, V.S, Gabibov, A.G, Wilmanns, M.
Deposit date:2013-01-28
Release date:2014-02-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Role of Kappa>Lambda Light-Chain Constant-Domain Switch in the Structure and Functionality of A17 Reactibody
Acta Crystallogr.,Sect.D, 70, 2014
4CKD
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BU of 4ckd by Molmil
Model of complex between the E.coli enzyme beta-galactosidase and four single chain Fv antibody domains scFv13R4.
Descriptor: BETA-GALACTOSIDASE, SCFV13R4 ANTIBODY FV HEAVY CHAIN, SCFV13R4 ANTIBODY FV LIGHT CHAIN
Authors:Vinothkumar, K.R, McMullan, G, Henderson, R.
Deposit date:2014-01-03
Release date:2014-01-15
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (13 Å)
Cite:Molecular Mechanism of Antibody-Mediated Activation of Beta-Galactosidase.
Structure, 22, 2014
4D9Q
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BU of 4d9q by Molmil
Inhibiting Alternative Pathway Complement Activation by Targeting the Exosite on Factor D
Descriptor: Anti-Factor D, heavy chain, light chain, ...
Authors:Murray, J.M, Wiesmann, C.
Deposit date:2012-01-11
Release date:2012-02-22
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Inhibiting alternative pathway complement activation by targeting the factor d exosite.
J.Biol.Chem., 287, 2012
4D9L
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BU of 4d9l by Molmil
Fab structure of anti-HIV-1 gp120 V2 mAb 697
Descriptor: Heavy chain of Fab fragment of anti-HIV1 gp120 V2 mAb 697, Light chain of Fab fragment of anti-HIV1 gp120 V2 mAb 697
Authors:Pan, R.M, Kong, X.P.
Deposit date:2012-01-11
Release date:2012-03-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.485 Å)
Cite:Functional and immunochemical cross-reactivity of V2-specific monoclonal antibodies from HIV-1-infected individuals.
Virology, 427, 2012
8CWK
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BU of 8cwk by Molmil
Fab arm of antibodies 4G1-C2 and 10G4 bound to CoV-2 receptor binding domain (RBD)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Heavy chain of Fab arm of antibody 10G4, ...
Authors:Langley, D.B, Christ, D.
Deposit date:2022-05-19
Release date:2023-05-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.368 Å)
Cite:Neutralization of CoV-2 omicron sublineages by affinity-matured class 5 antibodies
To Be Published
8E4C
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BU of 8e4c by Molmil
IgM BCR fab truncated form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, B-cell antigen receptor complex-associated protein alpha chain,Yellow fluorescent protein, B-cell antigen receptor complex-associated protein beta chain, ...
Authors:Dong, Y, Pi, X, Wu, H, Reth, M.
Deposit date:2022-08-18
Release date:2022-11-16
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural principles of B cell antigen receptor assembly.
Nature, 612, 2022
8ECZ
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BU of 8ecz by Molmil
Bovine Fab 4C1
Descriptor: 4C1 Fab heavy chain, 4C1 Fab light chain, PHOSPHATE ION
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2022-09-02
Release date:2023-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
8ECQ
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BU of 8ecq by Molmil
Bovine Fab 2G3
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2G3 Fab Heavy chain, 2G3 Fab Light chain, ...
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2022-09-02
Release date:2023-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EDF
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BU of 8edf by Molmil
Bovine Fab SKD in complex with Sars COV-2 receptor binding domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, SKD Fab Light chain, SKD Fab heavy chain, ...
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2022-09-04
Release date:2023-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023

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數據於2024-09-11公開中

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