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5F4V
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BU of 5f4v by Molmil
Crystal structure of the human sperm Izumo1 residues 22-268
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Izumo sperm-egg fusion protein 1
Authors:Aydin, H, Sultana, A, Lee, J.E.
Deposit date:2015-12-03
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular architecture of the human sperm IZUMO1 and egg JUNO fertilization complex.
Nature, 534, 2016
5F5J
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BU of 5f5j by Molmil
E.coli GlpG Y205F mutant complexed with aldehyde inhibitor in DMPC/CHAPSO bicelle
Descriptor: Rhomboid protease GlpG, peptidic derivative of Gurken: ACE-VAL-ARG-MET-ALA-aldehyde
Authors:Urban, S, Cho, S, Dickey, S.
Deposit date:2015-12-04
Release date:2016-02-10
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis.
Mol.Cell, 61, 2016
5F09
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BU of 5f09 by Molmil
Structure of inactive GCPII mutant in complex with beta-citryl glutamate
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Tykvart, J, Navratil, M, Pachl, P, Konvalinka, J.
Deposit date:2015-11-27
Release date:2016-06-01
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Comparison of human glutamate carboxypeptidases II and III reveals their divergent substrate specificities.
Febs J., 283, 2016
5Y3M
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BU of 5y3m by Molmil
Crystal structure of bovine TLR9 in complex with two DNAs (CpG DNA and TCGTTT DNA)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DNA (5'-D(*TP*CP*GP*T)-3'), DNA (5'-D(P*GP*GP*CP*GP*TP*T)-3'), ...
Authors:Ohto, U, Shimizu, T.
Deposit date:2017-07-29
Release date:2018-04-18
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Toll-like Receptor 9 Contains Two DNA Binding Sites that Function Cooperatively to Promote Receptor Dimerization and Activation
Immunity, 48, 2018
5F4Q
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BU of 5f4q by Molmil
Crystal structure of the human egg surface protein Juno
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ...
Authors:Aydin, H, Sultana, A, Lee, J.E.
Deposit date:2015-12-03
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular architecture of the human sperm IZUMO1 and egg JUNO fertilization complex.
Nature, 534, 2016
5F4T
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BU of 5f4t by Molmil
Crystal structure of the human sperm Izumo1 residues 22-254
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Izumo sperm-egg fusion protein 1
Authors:Aydin, H, Sultana, A, Lee, J.E.
Deposit date:2015-12-03
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.083 Å)
Cite:Molecular architecture of the human sperm IZUMO1 and egg JUNO fertilization complex.
Nature, 534, 2016
4XSS
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BU of 4xss by Molmil
Insulin-like growth factor I in complex with site 1 of a hybrid insulin receptor / Type 1 insulin-like growth factor receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin receptor, ...
Authors:Lawrence, C, Kong, G.K.-W, Menting, J.G, Lawrence, M.C.
Deposit date:2015-01-22
Release date:2015-06-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Congruency of Ligand Binding to the Insulin and Insulin/Type 1 Insulin-like Growth Factor Hybrid Receptors.
Structure, 23, 2015
5FG8
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BU of 5fg8 by Molmil
Drosophila CaMKII-wt in complex with a fragment of the Eag potassium channel and Mg2+/ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type II alpha chain, GLYCEROL, ...
Authors:Castro-Rodrigues, A.F, Morais-Cabral, J.H.
Deposit date:2015-12-20
Release date:2016-12-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.955 Å)
Cite:The Interaction between the Drosophila EAG Potassium Channel and the Protein Kinase CaMKII Involves an Extensive Interface at the Active Site of the Kinase.
J.Mol.Biol., 430, 2018
5F84
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BU of 5f84 by Molmil
Crystal structure of Drosophila Poglut1 (Rumi) complexed with its glycoprotein product (glucosylated EGF repeat) and UDP
Descriptor: Coagulation factor IX, O-glucosyltransferase rumi, SULFATE ION, ...
Authors:Yu, H.J, Li, H.L.
Deposit date:2015-12-09
Release date:2016-07-20
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural analysis of Notch-regulating Rumi reveals basis for pathogenic mutations.
Nat. Chem. Biol., 12, 2016
3FEC
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BU of 3fec by Molmil
Crystal structure of human Glutamate Carboxypeptidase III (GCPIII/NAALADase II), pseudo-unliganded
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ...
Authors:Barinka, C, Lubkowski, J, Hlouchova, K.
Deposit date:2008-11-28
Release date:2009-08-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Structural insight into the evolutionary and pharmacologic homology of glutamate carboxypeptidases II and III
Febs J., 276, 2009
3FF3
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BU of 3ff3 by Molmil
The high resolution structure of human glutamate carboxypeptidase III (GCPIII/NAALADase II) in complex with L-glutamate
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Lubkowski, J, Barinka, C.
Deposit date:2008-12-01
Release date:2009-08-25
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Structural insight into the evolutionary and pharmacologic homology of glutamate carboxypeptidases II and III
Febs J., 276, 2009
5VND
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BU of 5vnd by Molmil
Crystal structure of FGFR1-Y563C (FGFR4 surrogate) covalently bound to H3B-6527
Descriptor: 1,2-ETHANEDIOL, Fibroblast growth factor receptor 1, N-{2-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}pyrimidin-4-yl)amino]-5-(4-ethylpiperazin-1-yl)phenyl}propanamide, ...
Authors:Tsai, J.H.C, Reynolds, D, Fekkes, P, Smith, P, Larsen, N.A.
Deposit date:2017-04-30
Release date:2017-05-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma.
Cancer Res., 77, 2017
5WCU
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BU of 5wcu by Molmil
Crystal structure of 167 bp nucleosome bound to the globular domain of linker histone H5
Descriptor: DNA (167-MER), Histone H2A, Histone H2B, ...
Authors:Jiang, J.S, Zhou, B.R.
Deposit date:2017-07-02
Release date:2018-10-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (5.53 Å)
Cite:Revisit of Reconstituted 30-nm Nucleosome Arrays Reveals an Ensemble of Dynamic Structures.
J. Mol. Biol., 430, 2018
2OUJ
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BU of 2ouj by Molmil
The crystal structure of the Thrombospondin-1 N-terminal domain in complex with fractionated Heparin DP8
Descriptor: Thrombospondin-1
Authors:Tan, K, Joachimiak, A, Wang, J, Lawler, J.
Deposit date:2007-02-11
Release date:2008-01-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Heparin-induced cis- and trans-Dimerization Modes of the Thrombospondin-1 N-terminal Domain.
J.Biol.Chem., 283, 2008
5Y3L
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BU of 5y3l by Molmil
Crystal structure of horse TLR9 in complex with two DNAs (CpG DNA and CCGCAC DNA)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DNA (5'-D(*AP*GP*GP*CP*GP*TP*TP*TP*TP*T)-3'), ...
Authors:Ohto, U, Shimizu, T.
Deposit date:2017-07-29
Release date:2018-04-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Toll-like Receptor 9 Contains Two DNA Binding Sites that Function Cooperatively to Promote Receptor Dimerization and Activation
Immunity, 48, 2018
4GRS
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BU of 4grs by Molmil
Crystal structure of a chimeric DAH7PS
Descriptor: Phospho-2-dehydro-3-deoxyheptonate aldolase, 2-dehydro-3-deoxyphosphoheptonate aldolase, TYROSINE
Authors:Cross, P.J, Allison, T.M, Dobson, R.C.J, Jameson, G.B, Parker, E.J.
Deposit date:2012-08-26
Release date:2013-02-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Engineering allosteric control to an unregulated enzyme by transfer of a regulatory domain
Proc.Natl.Acad.Sci.USA, 110, 2013
4DBP
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BU of 4dbp by Molmil
Myosin VI nucleotide-free (MDINSERT2) D179Y crystal structure
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Calmodulin, ...
Authors:Pylypenko, O, Sweeney, H.L, Houdusse, A.
Deposit date:2012-01-16
Release date:2013-01-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mutations in myosin VI that cause a loss of coordination between heads provide insights into the structural changes underlying force generation and the importance of gating
To be Published
2OVO
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BU of 2ovo by Molmil
THE CRYSTAL AND MOLECULAR STRUCTURE OF THE THIRD DOMAIN OF SILVER PHEASANT OVOMUCOID (OMSVP3)
Descriptor: OVOMUCOID THIRD DOMAIN
Authors:Bode, W, Epp, O.
Deposit date:1985-06-11
Release date:1985-11-08
Last modified:2023-07-26
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The crystal and molecular structure of the third domain of silver pheasant ovomucoid (OMSVP3).
Eur.J.Biochem., 147, 1985
4YVI
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BU of 4yvi by Molmil
Crystal Structure of H. influenzae TrmD in complex with sinefungin and tRNA
Descriptor: SINEFUNGIN, tRNA, tRNA (guanine-N(1)-)-methyltransferase
Authors:Yoshida, K, Ito, T, Yokoyama, S.
Deposit date:2015-03-20
Release date:2015-07-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Structural basis for methyl-donor-dependent and sequence-specific binding to tRNA substrates by knotted methyltransferase TrmD.
Proc.Natl.Acad.Sci.USA, 112, 2015
3DMK
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BU of 3dmk by Molmil
Crystal structure of Down Syndrome Cell Adhesion Molecule (DSCAM) isoform 1.30.30, N-terminal eight Ig domains
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Down Syndrome Cell Adhesion Molecule (DSCAM) isoform 1.30.30, ...
Authors:Sawaya, M.R, Wojtowicz, W.M, Eisenberg, D, Zipursky, S.L.
Deposit date:2008-07-01
Release date:2008-10-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (4.19 Å)
Cite:A double S shape provides the structural basis for the extraordinary binding specificity of Dscam isoforms.
Cell(Cambridge,Mass.), 134, 2008
5WLE
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BU of 5wle by Molmil
Crystal structure of the PPS PHD finger in complex with H3K4me3
Descriptor: H3K4me3 Peptide, Protein partner of snf, isoform A, ...
Authors:Klein, B.J, Kutateladze, T.G.
Deposit date:2017-07-26
Release date:2017-10-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.952 Å)
Cite:A Unique pH-Dependent Recognition of Methylated Histone H3K4 by PPS and DIDO.
Structure, 25, 2017
5WLF
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BU of 5wlf by Molmil
Crystal structure of the apo PPS PHD finger
Descriptor: GLYCEROL, Protein partner of snf, isoform A, ...
Authors:Klein, B.J, Kutateladze, T.G.
Deposit date:2017-07-26
Release date:2017-10-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A Unique pH-Dependent Recognition of Methylated Histone H3K4 by PPS and DIDO.
Structure, 25, 2017
5X2M
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BU of 5x2m by Molmil
Crystal structure of the medaka fish taste receptor T1r2a-T1r3 ligand binding domains in complex with L-glutamine
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
Authors:Nuemket, N, Yasui, N, Atsumi, N, Yamashita, A.
Deposit date:2017-02-02
Release date:2017-05-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.206 Å)
Cite:Structural basis for perception of diverse chemical substances by T1r taste receptors
Nat Commun, 8, 2017
5WN9
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BU of 5wn9 by Molmil
Structure of antibody 2D10 bound to the central conserved region of RSV G
Descriptor: Major surface glycoprotein G, scFv 2D10
Authors:Fedechkin, S.O, George, N.L, Wolff, J.T, Kauvar, L.M, DuBois, R.M.
Deposit date:2017-07-31
Release date:2018-03-14
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.551 Å)
Cite:Structures of respiratory syncytial virus G antigen bound to broadly neutralizing antibodies.
Sci Immunol, 3, 2018
4FTB
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BU of 4ftb by Molmil
Crystal structure of the authentic Flock House virus particle
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ...
Authors:Speir, J.A, Chen, Z, Reddy, V.S, Johnson, J.E.
Deposit date:2012-06-27
Release date:2012-08-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural study of virus assembly intermediates reveals maturation event sequence and a staging position for externalized lytic peptides
to be published, 2012

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數據於2024-10-16公開中

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