5Y3M

Crystal structure of bovine TLR9 in complex with two DNAs (CpG DNA and TCGTTT DNA)

Summary for 5Y3M

• Entry DOI: 10.2210/pdb5y3m/pdb
• Descriptor: Toll-like receptor 9, DNA (5'-D(*TP*CP*GP*T)-3'), DNA (5'-D(P*GP*GP*CP*GP*TP*T)-3'), ... (5 entities in total)
• Functional Keywords: innate immunity, toll-like receptor, leucine-rich repeat, dna binding, immune system
• Biological source: Bos taurus (Bovine); More
• Total number of polymer chains: 6
• Total formula weight: 190571.57

Authors

Ohto, U.,Shimizu, T. (deposition date: 2017-07-29, release date: 2018-04-18, Last modification date: 2023-11-22)

• Primary citation: Ohto, U.,Ishida, H.,Shibata, T.,Sato, R.,Miyake, K.,Shimizu, T.; Toll-like Receptor 9 Contains Two DNA Binding Sites that Function Cooperatively to Promote Receptor Dimerization and Activation; Immunity, 48:649-658.e4, 2018; PubMed: 29625894; DOI: 10.1016/j.immuni.2018.03.013

Experimental method

X-RAY DIFFRACTION (2.5 Å)