5Y3M
Crystal structure of bovine TLR9 in complex with two DNAs (CpG DNA and TCGTTT DNA)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F (A, B) | Toll-like receptor 9 | polymer | 801 | 89323.5 | 2 | UniProt (Q5I2M5) Pfam (PF13855) Pfam (PF18837) Pfam (PF00560) | Bos taurus (Bovine) | |
| 2 | B, C (E, F) | DNA (5'-D(*TP*CP*GP*T)-3') | polymer | 6 | 1790.2 | 2 | synthetic construct | ||
| 3 | D, E (D, C) | DNA (5'-D(P*GP*GP*CP*GP*TP*T)-3') | polymer | 10 | 3066.0 | 2 | synthetic construct | ||
| 4 | G, H, I, J, K... (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 10 | Chemie (NAG) | |||
| 5 | Q, R, S, T (A, E, F, B) | water | water | 18.0 | 134 | Chemie (HOH) |
Sequence modifications
A, B: 25 - 817 (UniProt: Q5I2M5)
| PDB | External Database | Details |
|---|---|---|
| Arg 21 | - | expression tag |
| Ser 22 | - | expression tag |
| Pro 23 | - | expression tag |
| Trp 24 | - | expression tag |
| Glu 816 | Cys 816 | conflict |
| Leu 818 | - | expression tag |
| Val 819 | - | expression tag |
| Pro 820 | - | expression tag |
| Arg 821 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 188359.5 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2212.1 | |
| All* | Total formula weight | 190571.6 |
