5F09

Structure of inactive GCPII mutant in complex with beta-citryl glutamate

Summary for 5F09

• Entry DOI: 10.2210/pdb5f09/pdb
• Descriptor: Glutamate carboxypeptidase 2, TRIETHYLENE GLYCOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
• Functional Keywords: substrate, inactive variant, metallopeptidase, hydrolase
• Biological source: Homo sapiens (Human)
• Cellular location: Cell membrane ; Single-pass type II membrane protein . Isoform PSMA': Cytoplasm : Q04609
• Total number of polymer chains: 1
• Total formula weight: 86667.93

Authors

Tykvart, J.,Navratil, M.,Pachl, P.,Konvalinka, J. (deposition date: 2015-11-27, release date: 2016-06-01, Last modification date: 2024-01-10)

• Primary citation: Navratil, M.,Tykvart, J.,Schimer, J.,Pachl, P.,Navratil, V.,Rokob, T.A.,Hlouchova, K.,Rulisek, L.,Konvalinka, J.; Comparison of human glutamate carboxypeptidases II and III reveals their divergent substrate specificities.; Febs J., 283:2528-2545, 2016; PubMed: 27208881; DOI: 10.1111/febs.13761

Experimental method

X-RAY DIFFRACTION (1.85 Å)