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6X1G
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BU of 6x1g by Molmil
Crystal structure of a GEF domain from the Orientia tsutsugamushi protein OtDUB in complex with Rac1
Descriptor: MAGNESIUM ION, Ras-related C3 botulinum toxin substrate 1, ULP_PROTEASE domain-containing protein
Authors:Lim, C.S, Xiong, Y.
Deposit date:2020-05-18
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of a guanine nucleotide exchange factor encoded by the scrub typhus pathogen Orientia tsutsugamushi .
Proc.Natl.Acad.Sci.USA, 117, 2020
5XR1
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BU of 5xr1 by Molmil
Structure of FLN IG21 domain in complex with C-terminal peptide of beta-2
Descriptor: C-terminal peptide of Integrin beta-2,Filamin-A IG21 domain
Authors:Chatterjee, D, Lu, L.Z, Bhattacharjya, S.
Deposit date:2017-06-07
Release date:2018-06-13
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of FLN IG21 domain in complex with C-terminal peptide of beta-2
To Be Published
6LRQ
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BU of 6lrq by Molmil
Cryo-EM structure of A53T alpha-synuclein amyloid fibril
Descriptor: Alpha-synuclein
Authors:Sun, Y.P, Zhao, K, Liu, C.
Deposit date:2020-01-16
Release date:2020-04-08
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:Cryo-EM structure of full-length alpha-synuclein amyloid fibril with Parkinson's disease familial A53T mutation.
Cell Res., 30, 2020
6LTO
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BU of 6lto by Molmil
cryo-EM structure of full length human Pannexin1
Descriptor: Pannexin-1
Authors:Mou, L.Q, Ke, M, Xiao, Q.J, Wu, J.P, Deng, D.
Deposit date:2020-01-23
Release date:2020-05-13
Last modified:2020-05-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for gating mechanism of Pannexin 1 channel.
Cell Res., 30, 2020
1HJ0
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BU of 1hj0 by Molmil
Thymosin beta9
Descriptor: THYMOSIN BETA9
Authors:Stoll, R, Voelter, W, Holak, T.A.
Deposit date:2001-01-05
Release date:2002-01-04
Last modified:2024-04-24
Method:SOLUTION NMR
Cite:Conformation of Thymosin Beta9 in Water/Fluoroalcohol Solution Determined by NMR Spectroscopy
Biopolymers, 41, 1997
6M68
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BU of 6m68 by Molmil
The Cryo-EM Structure of Human Pannexin 1 in the Presence of CBX
Descriptor: Pannexin-1
Authors:Jin, Q, Bo, Z, Xiang, Z, Xiaokang, Z, Ye, S.
Deposit date:2020-03-13
Release date:2020-04-15
Last modified:2020-05-13
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Cryo-EM structures of human pannexin 1 channel.
Cell Res., 30, 2020
6M66
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BU of 6m66 by Molmil
The Cryo-EM Structure of Human Pannexin 1
Descriptor: Pannexin-1
Authors:Jin, Q, Bo, Z, Xiang, Z, Xiaokang, Z, Ye, S.
Deposit date:2020-03-13
Release date:2020-04-15
Last modified:2020-05-13
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Cryo-EM structures of human pannexin 1 channel.
Cell Res., 30, 2020
6LOJ
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BU of 6loj by Molmil
The complex structure of IpaH9.8-LRR and hGBP1
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Guanylate-binding protein 1, Invasion plasmid antigen
Authors:Ye, Y, Huang, H.
Deposit date:2020-01-06
Release date:2020-12-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.72 Å)
Cite:Substrate-binding destabilizes the hydrophobic cluster to relieve the autoinhibition of bacterial ubiquitin ligase IpaH9.8.
Commun Biol, 3, 2020
7S0Y
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BU of 7s0y by Molmil
Structures of TcdB in complex with Cdc42
Descriptor: Cell division control protein 42 homolog, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Zheng, L, Rongsheng, J, Peng, C.
Deposit date:2021-08-31
Release date:2021-09-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structural basis for selective modification of Rho and Ras GTPases by Clostridioides difficile toxin B.
Sci Adv, 7, 2021
6LTN
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BU of 6ltn by Molmil
cryo-EM structure of C-terminal truncated human Pannexin1
Descriptor: Pannexin-1
Authors:Mou, L.Q, Ke, M, Xiao, Q.J, Wu, J.P, Deng, D.
Deposit date:2020-01-23
Release date:2020-05-13
Last modified:2020-05-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for gating mechanism of Pannexin 1 channel.
Cell Res., 30, 2020
6M02
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BU of 6m02 by Molmil
cryo-EM structure of human Pannexin 1 channel
Descriptor: Pannexin-1
Authors:Ronggui, Q, Lili, D, Jilin, Z, Xuekui, Y, Lei, W, Shujia, Z.
Deposit date:2020-02-19
Release date:2020-03-25
Last modified:2020-05-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of human heptameric Pannexin 1 channel.
Cell Res., 30, 2020
4GZL
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BU of 4gzl by Molmil
Crystal structure of RAC1 Q61L mutant
Descriptor: ISOPROPYL ALCOHOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Ha, B.H, Boggon, T.J.
Deposit date:2012-09-06
Release date:2012-12-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:RAC1P29S is a spontaneously activating cancer-associated GTPase.
Proc.Natl.Acad.Sci.USA, 110, 2013
7STY
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BU of 7sty by Molmil
Crystal structure of human CORO1C
Descriptor: Coronin-1C
Authors:Zeng, H, Dong, A, Hutchinson, A, Seitova, A, Loppnau, P, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC)
Deposit date:2021-11-15
Release date:2021-12-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of human CORO1C
To Be Published
6N8S
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BU of 6n8s by Molmil
Crystal structure of the human cell polarity protein Lethal Giant Larvae 2 (Lgl2). aPKC phosphorylated, crystal form 3.
Descriptor: Lethal(2) giant larvae protein homolog 2
Authors:Almagor, L, Weis, W.I.
Deposit date:2018-11-30
Release date:2019-05-08
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural insights into the aPKC regulatory switch mechanism of the human cell polarity protein lethal giant larvae 2.
Proc.Natl.Acad.Sci.USA, 116, 2019
6N8R
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BU of 6n8r by Molmil
Crystal structure of the human cell polarity protein Lethal Giant Larvae 2 (Lgl2). aPKC phosphorylated, crystal form 2.
Descriptor: CHLORIDE ION, GLYCEROL, Lethal(2) giant larvae protein homolog 2
Authors:Almagor, L, Weis, W.I.
Deposit date:2018-11-30
Release date:2019-05-08
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structural insights into the aPKC regulatory switch mechanism of the human cell polarity protein lethal giant larvae 2.
Proc.Natl.Acad.Sci.USA, 116, 2019
6N8Q
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BU of 6n8q by Molmil
Crystal structure of the human cell polarity protein Lethal Giant Larvae 2 (Lgl2). Unphosphorylated, crystal form 2.
Descriptor: CHLORIDE ION, GLYCEROL, Lethal(2) giant larvae protein homolog 2
Authors:Almagor, L, Weis, W.I.
Deposit date:2018-11-30
Release date:2019-05-08
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural insights into the aPKC regulatory switch mechanism of the human cell polarity protein lethal giant larvae 2.
Proc.Natl.Acad.Sci.USA, 116, 2019
6N8P
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BU of 6n8p by Molmil
Crystal structure of the human cell polarity protein Lethal Giant Larvae 2 (Lgl2). Unphosphorylated, crystal form 1.
Descriptor: CHLORIDE ION, Lethal(2) giant larvae protein homolog 2
Authors:Almagor, L, Weis, W.I.
Deposit date:2018-11-30
Release date:2019-05-08
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.193 Å)
Cite:Structural insights into the aPKC regulatory switch mechanism of the human cell polarity protein lethal giant larvae 2.
Proc.Natl.Acad.Sci.USA, 116, 2019
8FC8
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BU of 8fc8 by Molmil
Cryo-EM structure of the human TRPV4 in complex with GSK1016790A
Descriptor: CHOLESTEROL HEMISUCCINATE, N-[(2S)-1-{4-[N-(2,4-dichlorobenzene-1-sulfonyl)-L-seryl]piperazin-1-yl}-4-methyl-1-oxopentan-2-yl]-1-benzothiophene-2-carboxamide, Transient receptor potential cation channel subfamily V member 4
Authors:Kwon, D.H, Lee, S.-Y, Zhang, F.
Deposit date:2022-12-01
Release date:2023-07-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease.
Nat Commun, 14, 2023
8FCA
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BU of 8fca by Molmil
Cryo-EM structure of the human TRPV4 - RhoA in complex with 4alpha-Phorbol 12,13-didecanoate
Descriptor: (1aR,1bS,4aS,7aS,7bS,8R,9R,9aS)-9a-(decanoyloxy)-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yl decanoate, CHOLESTEROL HEMISUCCINATE, Transient receptor potential cation channel subfamily V member 4
Authors:Kwon, D.H, Lee, S.-Y, Zhang, F.
Deposit date:2022-12-01
Release date:2023-07-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease.
Nat Commun, 14, 2023
4GZM
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BU of 4gzm by Molmil
Crystal structure of RAC1 F28L mutant
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Ras-related C3 botulinum toxin substrate 1
Authors:Ha, B.H, Boggon, T.J.
Deposit date:2012-09-06
Release date:2012-12-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:RAC1P29S is a spontaneously activating cancer-associated GTPase.
Proc.Natl.Acad.Sci.USA, 110, 2013
8WH5
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BU of 8wh5 by Molmil
Structure of DDM1-nucleosome complex in the apo state
Descriptor: ATP-dependent DNA helicase DDM1, DNA (antisense strand), DNA (sense strand), ...
Authors:Liu, Y, Zhang, Z, Du, J.
Deposit date:2023-09-22
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation.
Nat.Plants, 10, 2024
8WHA
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BU of 8wha by Molmil
Structure of DDM1-nucleosome complex in the ADP-BeFx state with DDM1 bound to SHL2 and SHL-2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase DDM1, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Liu, Y, Zhang, Z, Du, J.
Deposit date:2023-09-22
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (4.05 Å)
Cite:Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation.
Nat.Plants, 10, 2024
8WH9
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BU of 8wh9 by Molmil
Structure of DDM1-nucleosome complex in ADP-BeFx state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase DDM1, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Liu, Y, Zhang, Z, Du, J.
Deposit date:2023-09-22
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation.
Nat.Plants, 10, 2024
6M7A
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BU of 6m7a by Molmil
Structure of REV7-R124A complexed with SHLD3(28-73)
Descriptor: Mitotic spindle assembly checkpoint protein MAD2B, Shieldin complex subunit 3
Authors:Ma, Y.Z, Li, Y, Wu, B.X, Huang, H.D.
Deposit date:2020-03-18
Release date:2021-01-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of REV7-R124A complexed with SHLD3(28-73)
To Be Published
8WH8
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BU of 8wh8 by Molmil
Structure of DDM1-nucleosome complex in ADP state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase DDM1, DNA (antisense strand), ...
Authors:Liu, Y, Zhang, Z, Du, J.
Deposit date:2023-09-22
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation.
Nat.Plants, 10, 2024

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數據於2024-07-31公開中

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