6N8R

Crystal structure of the human cell polarity protein Lethal Giant Larvae 2 (Lgl2). aPKC phosphorylated, crystal form 2.

Summary for 6N8R

Entry DOI	10.2210/pdb6n8r/pdb
Descriptor	Lethal(2) giant larvae protein homolog 2, CHLORIDE ION, GLYCEROL, ... (4 entities in total)
Functional Keywords	lgl, polarity, beta propeller, lipid binding protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	109402.66
Authors	Almagor, L.,Weis, W.I. (deposition date: 2018-11-30, release date: 2019-05-08, Last modification date: 2024-03-13)
Primary citation	Almagor, L.,Ufimtsev, I.S.,Ayer, A.,Li, J.,Weis, W.I. Structural insights into the aPKC regulatory switch mechanism of the human cell polarity protein lethal giant larvae 2. Proc.Natl.Acad.Sci.USA, 116:10804-10812, 2019 Cited by PubMed: 31088962 DOI: 10.1073/pnas.1821514116 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.91 Å)

Structure validation