6X1G

Crystal structure of a GEF domain from the Orientia tsutsugamushi protein OtDUB in complex with Rac1

Summary for 6X1G

Entry DOI	10.2210/pdb6x1g/pdb
Descriptor	ULP_PROTEASE domain-containing protein, Ras-related C3 botulinum toxin substrate 1, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	guanine nucleotide exchange factor, gef, rac1, gtpase, orientia tsutsugamushi, scrub typhus, signaling protein, signaling protein-hydrolase complex, signaling protein/hydrolase
Biological source	Orientia tsutsugamushi (Rickettsia tsutsugamushi) More
Total number of polymer chains	4
Total formula weight	91484.66
Authors	Lim, C.S.,Xiong, Y. (deposition date: 2020-05-18, release date: 2020-11-25, Last modification date: 2023-10-18)
Primary citation	Lim, C.,Berk, J.M.,Blaise, A.,Bircher, J.,Koleske, A.J.,Hochstrasser, M.,Xiong, Y. Crystal structure of a guanine nucleotide exchange factor encoded by the scrub typhus pathogen Orientia tsutsugamushi . Proc.Natl.Acad.Sci.USA, 117:30380-30390, 2020 Cited by PubMed: 33184172 DOI: 10.1073/pnas.2018163117 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation