6N8S
Crystal structure of the human cell polarity protein Lethal Giant Larvae 2 (Lgl2). aPKC phosphorylated, crystal form 3.
Summary for 6N8S
| Entry DOI | 10.2210/pdb6n8s/pdb |
| Descriptor | Lethal(2) giant larvae protein homolog 2 (1 entity in total) |
| Functional Keywords | lgl, polarity, beta propeller, lipid binding protein |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 218550.22 |
| Authors | Almagor, L.,Weis, W.I. (deposition date: 2018-11-30, release date: 2019-05-08, Last modification date: 2024-03-13) |
| Primary citation | Almagor, L.,Ufimtsev, I.S.,Ayer, A.,Li, J.,Weis, W.I. Structural insights into the aPKC regulatory switch mechanism of the human cell polarity protein lethal giant larvae 2. Proc.Natl.Acad.Sci.USA, 116:10804-10812, 2019 Cited by PubMed: 31088962DOI: 10.1073/pnas.1821514116 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.9 Å) |
Structure validation
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