1BZQ
 
 | | COMPLEX OF A DROMEDARY SINGLE-DOMAIN VHH ANTIBODY FRAGMENT WITH RNASE A | | Descriptor: | PHOSPHATE ION, PROTEIN (ANTIBODY CAB-RN05), PROTEIN (RNASE A) | | Authors: | Decanniere, K, Desmyter, A, Gahroudhi, M, Lauwereys, M, Muyldermans, S, Wyns, L. | | Deposit date: | 1998-11-03 | | Release date: | 1998-11-11 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | A single-domain antibody fragment in complex with RNase A: non-canonical loop structures and nanomolar affinity using two CDR loops.
Structure Fold.Des., 7, 1999
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2HKY
 | | NMR solution structure of human RNase 7 | | Descriptor: | Ribonuclease 7 | | Authors: | Huang, Y.-C, Chen, C, Lou, Y.-C. | | Deposit date: | 2006-07-06 | | Release date: | 2006-12-26 | | Last modified: | 2022-03-09 | | Method: | SOLUTION NMR | | Cite: | The flexible and clustered lysine residues of human ribonuclease 7 are critical for membrane permeability and antimicrobial activity.
J.Biol.Chem., 282, 2007
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1M07
 | | RESIDUES INVOLVED IN THE CATALYSIS AND BASE SPECIFICITY OF CYTOTOXIC RIBONUCLEASE FROM BULLFROG (RANA CATESBEIANA) | | Descriptor: | 5'-D(*AP*CP*GP*A)-3', Ribonuclease | | Authors: | Leu, Y.-J, Chern, S.-S, Wang, S.-C, Hsiao, Y.-Y, Amiraslanov, I, Liaw, Y.-C, Liao, Y.-D. | | Deposit date: | 2002-06-12 | | Release date: | 2003-01-21 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Residues involved in the catalysis, base specificity, and cytotoxicity of ribonuclease from Rana catesbeiana based upon mutagenesis and X-ray crystallography
J.Biol.Chem., 278, 2003
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2APQ
 | | Crystal Structure of an Active Site Mutant of Bovine Pancreatic Ribonuclease A (H119A-RNase A) with a 10-Glutamine expansion in the C-terminal hinge-loop. | | Descriptor: | PHOSPHATE ION, Ribonuclease | | Authors: | Sambashivan, S, Liu, Y, Sawaya, M.R, Gingery, M, Eisenberg, D. | | Deposit date: | 2005-08-16 | | Release date: | 2005-09-13 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Amyloid-like fibrils of ribonuclease A with three-dimensional domain-swapped and native-like structure.
Nature, 437, 2005
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1XHP
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1JS0
 | | Crystal Structure of 3D Domain-swapped RNase A Minor Trimer | | Descriptor: | RIBONUCLEASE A, SULFATE ION | | Authors: | Liu, Y, Gotte, G, Libonati, M, Eisenberg, D. | | Deposit date: | 2001-08-15 | | Release date: | 2002-03-13 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structures of the two 3D domain-swapped RNase A trimers.
Protein Sci., 11, 2002
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6ENP
 | | Atomic resolution structure of human RNase 6 in the presence of phosphate anions in P21 space group. | | Descriptor: | CHLORIDE ION, PHOSPHATE ION, Ribonuclease K6, ... | | Authors: | Prats-Ejarque, G, Moussaoui, M, Boix, E. | | Deposit date: | 2017-10-05 | | Release date: | 2018-10-24 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.042 Å) | | Cite: | Characterization of an RNase with two catalytic centers. Human RNase6 catalytic and phosphate-binding site arrangement favors the endonuclease cleavage of polymeric substrates.
Biochim Biophys Acta Gen Subj, 1863, 2019
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5ET4
 | | Structure of RNase A-K7H/R10H in complex with 3'-CMP | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CYTIDINE-3'-MONOPHOSPHATE, Ribonuclease pancreatic | | Authors: | Blanco, J.A, Salazar, V.A, Moussaoui, M, Boix, E. | | Deposit date: | 2015-11-17 | | Release date: | 2016-11-30 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Characterization of an RNase with two catalytic centers. Human RNase6 catalytic and phosphate-binding site arrangement favors the endonuclease cleavage of polymeric substrates.
Biochim Biophys Acta Gen Subj, 1863, 2019
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4L55
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1RAS
 | | CRYSTAL STRUCTURE OF A FLUORESCENT DERIVATIVE OF RNASE A | | Descriptor: | 5-(1-SULFONAPHTHYL)-ACETYLAMINO-ETHYLAMINE, RIBONUCLEASE A | | Authors: | Baudet-Nessler, S, Jullien, M, Crosio, M.-P, Janin, J. | | Deposit date: | 1993-03-02 | | Release date: | 1993-10-31 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure of a fluorescent derivative of RNase A.
Biochemistry, 32, 1993
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1RAR
 | | CRYSTAL STRUCTURE OF A FLUORESCENT DERIVATIVE OF RNASE A | | Descriptor: | 5-(1-SULFONAPHTHYL)-ACETYLAMINO-ETHYLAMINE, CHLORIDE ION, RIBONUCLEASE A | | Authors: | Baudet-Nessler, S, Jullien, M, Crosio, M.-P, Janin, J. | | Deposit date: | 1993-03-02 | | Release date: | 1993-10-31 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of a fluorescent derivative of RNase A.
Biochemistry, 32, 1993
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5OAB
 | | A novel crystal form of human RNase6 at atomic resolution | | Descriptor: | CHLORIDE ION, PHOSPHATE ION, POTASSIUM ION, ... | | Authors: | Prats-Ejarque, G, Moussaoui, M, Boix, E. | | Deposit date: | 2017-06-21 | | Release date: | 2018-08-01 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.111 Å) | | Cite: | Characterization of an RNase with two catalytic centers. Human RNase6 catalytic and phosphate-binding site arrangement favors the endonuclease cleavage of polymeric substrates.
Biochim Biophys Acta Gen Subj, 1863, 2019
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2F87
 | | Solution structure of a GAAG tetraloop in SRP RNA from Pyrococcus furiosus | | Descriptor: | SRP RNA | | Authors: | Okada, K, Takahashi, M, Sakamoto, T, Nakamura, K, Kanai, A, Kawai, G | | Deposit date: | 2005-12-02 | | Release date: | 2006-08-08 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of a GAAG tetraloop in helix 6 of SRP RNA from Pyrococcus furiosus
Nucleosides Nucleotides Nucleic Acids, 25, 2006
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3CW5
 | | E. coli Initiator tRNA | | Descriptor: | Initiator tRNA | | Authors: | Barraud, P, Schmitt, E, Mechulam, Y, Dardel, F, Tisne, C. | | Deposit date: | 2008-04-21 | | Release date: | 2008-09-02 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | A unique conformation of the anticodon stem-loop is associated with the capacity of tRNAfMet to initiate protein synthesis.
Nucleic Acids Res., 36, 2008
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1F0V
 | | Crystal structure of an Rnase A dimer displaying a new type of 3D domain swapping | | Descriptor: | 5'-D(*CP*G)-3', GLYCEROL, PHOSPHATE ION, ... | | Authors: | Liu, Y.S, Gotte, G, Libonati, M, Eisenberg, D.S. | | Deposit date: | 2000-05-17 | | Release date: | 2001-02-21 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | A domain-swapped RNase A dimer with implications for amyloid formation
Nat.Struct.Biol., 8, 2001
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3CW6
 | | E. coli Initiator tRNA | | Descriptor: | Initiator tRNA | | Authors: | Barraud, P, Schmitt, E, Mechulam, Y, Dardel, F, Tisne, C. | | Deposit date: | 2008-04-21 | | Release date: | 2008-09-02 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | A unique conformation of the anticodon stem-loop is associated with the capacity of tRNAfMet to initiate protein synthesis.
Nucleic Acids Res., 36, 2008
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3F8G
 | | The X-ray structure of a dimeric variant of human pancreatic ribonuclease with high cytotoxic and antitumor activities | | Descriptor: | Ribonuclease pancreatic, SULFATE ION | | Authors: | Merlino, A, Avella, G, Mazzarella, L, Sica, F. | | Deposit date: | 2008-11-12 | | Release date: | 2009-02-10 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural features for the mechanism of antitumor action of a dimeric human pancreatic ribonuclease variant.
Protein Sci., 18, 2009
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3FKZ
 | | X-ray structure of the non covalent swapped form of the S16G/T17N/A19P/A20S/K31C/S32C mutant of bovine pancreatic ribonuclease | | Descriptor: | Ribonuclease pancreatic | | Authors: | Merlino, A, Russo Krauss, I, Perillo, M, Mattia, C.A, Ercole, C, Picone, D, Vergara, A, Sica, F. | | Deposit date: | 2008-12-18 | | Release date: | 2009-03-24 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Toward an antitumor form of bovine pancreatic ribonuclease: The crystal structure of three noncovalent dimeric mutants
Biopolymers, 91, 2009
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3FL3
 | | X-ray structure of the ligand free non covalent swapped form of the A19P/Q28L/K31C/S32C mutant of bovine pancreatic ribonuclease | | Descriptor: | Ribonuclease pancreatic, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose | | Authors: | Merlino, A, Russo Krauss, I, Perillo, M, Mattia, C.A, Ercole, C, Picone, D, Vergara, A, Sica, F. | | Deposit date: | 2008-12-18 | | Release date: | 2009-03-24 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Toward an antitumor form of bovine pancreatic ribonuclease: The crystal structure of three noncovalent dimeric mutants
Biopolymers, 91, 2009
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3FL0
 | | X-ray structure of the non covalent swapped form of the Q28L/K31C/S32C mutant of bovine pancreatic ribonuclease in complex with 2'-DEOXYCYTIDINE-2'-DEOXYGUANOSINE-3',5'-MONOPHOSPHATE | | Descriptor: | 2'-DEOXYCYTIDINE-2'-DEOXYGUANOSINE-3',5'-MONOPHOSPHATE, Ribonuclease pancreatic | | Authors: | Merlino, A, Russo Krauss, I, Perillo, M, Mattia, C.A, Ercole, C, Picone, D, Vergara, A, Sica, F. | | Deposit date: | 2008-12-18 | | Release date: | 2009-03-24 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Toward an antitumor form of bovine pancreatic ribonuclease: The crystal structure of three noncovalent dimeric mutants
Biopolymers, 91, 2009
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3FL1
 | | X-ray structure of the non covalent swapped form of the A19P/Q28L/K31C/S32C mutant of bovine pancreatic ribonuclease in complex with 2'-DEOXYCYTIDINE-2'-DEOXYGUANOSINE-3',5'-MONOPHOSPHATE | | Descriptor: | 2'-DEOXYCYTIDINE-2'-DEOXYGUANOSINE-3',5'-MONOPHOSPHATE, Ribonuclease pancreatic, SULFATE ION, ... | | Authors: | Merlino, A, Russo Krauss, I, Perillo, M, Mattia, C.A, Ercole, C, Picone, D, Vergara, A, Sica, F. | | Deposit date: | 2008-12-18 | | Release date: | 2009-03-24 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Toward an antitumor form of bovine pancreatic ribonuclease: The crystal structure of three noncovalent dimeric mutants
Biopolymers, 91, 2009
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2QCA
 | | A New Crystal Form of Bovine Pancreatic RNase A in Complex with 2'-Deoxyguanosine-5'-monophosphate | | Descriptor: | 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, Ribonuclease pancreatic | | Authors: | Larson, S.B, Day, J.S, Cudney, R, McPherson, A, Center for High-Throughput Structural Biology (CHTSB) | | Deposit date: | 2007-06-19 | | Release date: | 2007-07-03 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.33 Å) | | Cite: | A new crystal form of bovine pancreatic RNase A in complex with 2'-deoxyguanosine-5'-monophosphate.
Acta Crystallogr.,Sect.F, 63, 2007
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5OGH
 | | Structure of RNase A at high resolution (1.16 A) in complex with 3'-CMP and sulphate ions | | Descriptor: | CHLORIDE ION, CYTIDINE-3'-MONOPHOSPHATE, Ribonuclease pancreatic, ... | | Authors: | Blanco, J.A, Prats-Ejarque, G, Salazar, V.A, Moussaoui, M, Boix, E. | | Deposit date: | 2017-07-13 | | Release date: | 2018-08-01 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.16 Å) | | Cite: | Characterization of an RNase with two catalytic centers. Human RNase6 catalytic and phosphate-binding site arrangement favors the endonuclease cleavage of polymeric substrates.
Biochim Biophys Acta Gen Subj, 1863, 2019
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1RPH
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1RPG
 | | STRUCTURES OF RNASE A COMPLEXED WITH 3'-CMP AND D(CPA): ACTIVE SITE CONFORMATION AND CONSERVED WATER MOLECULES | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2'-DEOXYCYTIDINE-2'-DEOXYADENOSINE-3',5'-MONOPHOSPHATE, RIBONUCLEASE A | | Authors: | Zegers, I, Wyns, L, Palmer, R. | | Deposit date: | 1994-08-29 | | Release date: | 1994-12-20 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | The structures of RNase A complexed with 3'-CMP and d(CpA): active site conformation and conserved water molecules.
Protein Sci., 3, 1994
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