5ET4
Structure of RNase A-K7H/R10H in complex with 3'-CMP
Summary for 5ET4
Entry DOI | 10.2210/pdb5et4/pdb |
Related | 4U7R |
Descriptor | Ribonuclease pancreatic, CYTIDINE-3'-MONOPHOSPHATE, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total) |
Functional Keywords | rnase a, p2 subsite, exonuclease activity, hydrolase |
Biological source | Bos taurus (Bovine) More |
Total number of polymer chains | 4 |
Total formula weight | 56203.95 |
Authors | Blanco, J.A.,Salazar, V.A.,Moussaoui, M.,Boix, E. (deposition date: 2015-11-17, release date: 2016-11-30, Last modification date: 2024-01-10) |
Primary citation | Prats-Ejarque, G.,Blanco, J.A.,Salazar, V.A.,Nogues, V.M.,Moussaoui, M.,Boix, E. Characterization of an RNase with two catalytic centers. Human RNase6 catalytic and phosphate-binding site arrangement favors the endonuclease cleavage of polymeric substrates. Biochim Biophys Acta Gen Subj, 1863:105-117, 2019 Cited by PubMed: 30287244DOI: 10.1016/j.bbagen.2018.09.021 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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