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5HX8
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BU of 5hx8 by Molmil
Jak1 complex with 4-[(4-aminocyclohexyl)amino]-3-(1H-benzimidazol-2-yl)-1H-pyridin-2-one
Descriptor: 4-[(4-aminocyclohexyl)amino]-3-(1H-benzimidazol-2-yl)-1H-pyridin-2-one, Tyrosine-protein kinase JAK1
Authors:Su, H.P.
Deposit date:2016-01-29
Release date:2016-03-16
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-based design and development of (benz)imidazole pyridones as JAK1-selective kinase inhibitors.
Bioorg.Med.Chem.Lett., 26, 2016
5IW8
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BU of 5iw8 by Molmil
Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 4 [5-(3-([1,1'-Biphenyl]-3-yl)ureido)-2-hydroxybenzoic acid]
Descriptor: 5-{[([1,1'-biphenyl]-3-yl)carbamoyl]amino}-2-hydroxybenzoic acid, O-phosphoserine sulfhydrylase, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Brunner, K, Schnell, R, Schneider, G.
Deposit date:2016-03-22
Release date:2016-08-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.
J.Med.Chem., 59, 2016
5IXE
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BU of 5ixe by Molmil
1.75A RESOLUTION STRUCTURE OF 5-Fluoroindole BOUND BETA-GLYCOSIDASE (W33G) FROM SULFOLOBUS SOLFATARICUS
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 5-fluoro-1H-indole, Beta-galactosidase, ...
Authors:Lovell, S, Battaile, K.P, Mehzabeen, N, Budiardjo, S.J, Karanicolas, J.
Deposit date:2016-03-23
Release date:2016-07-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Full and Partial Agonism of a Designed Enzyme Switch.
ACS Synth Biol, 5, 2016
5IT0
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BU of 5it0 by Molmil
Crystal structure of Mycobacterium avium SerB2 mutant D343N/D347N
Descriptor: MAGNESIUM ION, Phosphoserine phosphatase
Authors:Shree, S, Ramachandran, R.
Deposit date:2016-03-16
Release date:2016-04-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.968 Å)
Cite:Crystal Structure of Mycobacterium avium SerB2 (MAV_3907) active site mutant D343N/D347N
To be published
5IWC
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BU of 5iwc by Molmil
Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 3 [4-(3-([1,1'-Biphenyl]-3-yl)ureido)-2-hydroxybenzoic acid]
Descriptor: 4-{[([1,1'-biphenyl]-3-yl)carbamoyl]amino}-2-hydroxybenzoic acid, O-phosphoserine sulfhydrylase, PYRIDOXAL-5'-PHOSPHATE
Authors:Schnell, R, Maric, S, Lindqvist, Y, Schneider, G.
Deposit date:2016-03-22
Release date:2016-08-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.
J.Med.Chem., 59, 2016
5JGP
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BU of 5jgp by Molmil
Crystal structure of the nitrate/nitrite sensor NarQ fragment bound with iodide ions
Descriptor: IODIDE ION, NITRATE ION, Nitrate/nitrite sensor protein NarQ
Authors:Melnikov, I, Polovinkin, V, Popov, A, Gordeliy, V.
Deposit date:2016-04-20
Release date:2017-05-31
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Fast iodide-SAD phasing for high-throughput membrane protein structure determination.
Sci Adv, 3, 2017
5JLR
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BU of 5jlr by Molmil
Crystal structure of Mycobacterium avium SerB2 with serine present at slightly different position near ACT domain
Descriptor: 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, MAGNESIUM ION, ...
Authors:Shree, S, Agrawal, A, Dubey, S, Ramachandran, R.
Deposit date:2016-04-27
Release date:2017-05-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.261 Å)
Cite:Crystal structure of Mycobacterium avium SerB2 with serine present at slightly different position near ACT domain
To be published
6KR5
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BU of 6kr5 by Molmil
Crystal structure of O-Acetyl Serine Sulfhydrylase isoform 3 from Entamoeba histolytica
Descriptor: Cysteine synthase 3, PYRIDOXAL-5'-PHOSPHATE
Authors:Dharavath, S, Gourinath, S.
Deposit date:2019-08-21
Release date:2020-09-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.544 Å)
Cite:Crystal structure of O-Acetylserine sulfhydralase (OASS) isoform 3 from Entamoeba histolytica: Pharmacophore-based virtual screening and validation of novel inhibitors.
Eur.J.Med.Chem., 192, 2020
6KUT
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BU of 6kut by Molmil
Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B2)
Descriptor: 3'-vRNA, 5'-vRNA, Polymerase 3, ...
Authors:Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y.
Deposit date:2019-09-02
Release date:2019-10-02
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019
6KV5
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BU of 6kv5 by Molmil
Structure of influenza D virus apo polymerase
Descriptor: Polymerase 3, Polymerase PB2, RNA-directed RNA polymerase catalytic subunit
Authors:Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y.
Deposit date:2019-09-03
Release date:2019-10-02
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019
6LDX
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BU of 6ldx by Molmil
Structure antibody E6 in complex with methylated peptide
Descriptor: CHLORIDE ION, Fab Heavy chain, Fab light chain, ...
Authors:Caaveiro, J.M.M, Tsumoto, K.
Deposit date:2019-11-23
Release date:2020-11-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for antigen recognition by methylated lysine-specific antibodies.
J.Biol.Chem., 296, 2020
6KUJ
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BU of 6kuj by Molmil
Structure of influenza D virus polymerase bound to cRNA promoter in class 1
Descriptor: 3'-cRNA promoter, 5'-cRNA promoter, Polymerase 3, ...
Authors:Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y.
Deposit date:2019-09-02
Release date:2019-10-02
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of influenza D virus polymerase bound to cRNA promoter in Mode A conformation
NAT NANOTECHNOL, 2019
6LDY
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BU of 6ldy by Molmil
Structure antibody D6 in complex with methylated peptide
Descriptor: CALCIUM ION, CHLORIDE ION, Fab heavy chain, ...
Authors:Caaveiro, J.M.M, Tsumoto, K.
Deposit date:2019-11-23
Release date:2020-11-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structural basis for antigen recognition by methylated lysine-specific antibodies.
J.Biol.Chem., 296, 2020
6LDW
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BU of 6ldw by Molmil
Structure of antibody C9 in complex with methylated peptide
Descriptor: CHLORIDE ION, Fab heavy chain, Fab light chain, ...
Authors:Caaveiro, J.M.M, Tsumoto, K.
Deposit date:2019-11-23
Release date:2020-11-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis for antigen recognition by methylated lysine-specific antibodies.
J.Biol.Chem., 296, 2020
6LDV
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BU of 6ldv by Molmil
Structure antibody F9 in complex with methylated peptide
Descriptor: Fab heavy chain, Fab light chain, GLY-M3L-GLY-GLY-THR-TYR-PRO, ...
Authors:Caaveiro, J.M.M, Tsumoto, K.
Deposit date:2019-11-23
Release date:2020-11-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for antigen recognition by methylated lysine-specific antibodies.
J.Biol.Chem., 296, 2020
5VSU
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BU of 5vsu by Molmil
Structure of yeast U6 snRNP with 2'-phosphate terminated U6 RNA
Descriptor: Saccharomyces cerevisiae strain T8 chromosome XII sequence, U4/U6 snRNA-associated-splicing factor PRP24, U6 snRNA-associated Sm-like protein LSm2, ...
Authors:Montemayor, E.J.
Deposit date:2017-05-12
Release date:2018-05-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Architecture of the U6 snRNP reveals specific recognition of 3'-end processed U6 snRNA.
Nat Commun, 9, 2018
5VKQ
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BU of 5vkq by Molmil
Structure of a mechanotransduction ion channel Drosophila NOMPC in nanodisc
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, No mechanoreceptor potential C isoform L
Authors:Jin, P, Bulkley, D, Guo, Y, Zhang, W, Guo, Z, Huynh, W, Wu, S, Meltzer, S, Chen, T, Jan, L.Y, Jan, Y.-N, Cheng, Y.
Deposit date:2017-04-22
Release date:2017-06-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Electron cryo-microscopy structure of the mechanotransduction channel NOMPC.
Nature, 547, 2017
6M2V
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BU of 6m2v by Molmil
Crystal structure of UHRF1 SRA complexed with fully-mCHG DNA.
Descriptor: DNA (5'-D(*TP*CP*AP*CP*GP*(5CM)P*TP*GP*CP*GP*TP*GP*A)-3'), E3 ubiquitin-protein ligase UHRF1
Authors:Abhishek, S, Nakarakanti, N.K, Deeksha, W, Rajakumara, E.
Deposit date:2020-03-01
Release date:2021-01-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Mechanistic insights into recognition of symmetric methylated cytosines in CpG and non-CpG DNA by UHRF1 SRA.
Int.J.Biol.Macromol., 170, 2021
8WQL
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BU of 8wql by Molmil
In situ PBS-PSII supercomplex from cyanobacterial Spirulina platensis
Descriptor: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
Authors:You, X, Zhang, X, Xiao, Y.N, Sun, S, Sui, S.F.
Deposit date:2023-10-11
Release date:2024-07-31
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of in situ PBS-PSII supercomplex at 3.5 Angstroms resolution.
To Be Published
6M4O
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BU of 6m4o by Molmil
Cryo-EM structure of the monomeric SPT-ORMDL3 complex
Descriptor: ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ...
Authors:Li, S.S, Xie, T, Wang, L, Gong, X.
Deposit date:2020-03-08
Release date:2021-02-10
Last modified:2021-03-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural insights into the assembly and substrate selectivity of human SPT-ORMDL3 complex.
Nat.Struct.Mol.Biol., 28, 2021
6M4N
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BU of 6m4n by Molmil
Cryo-EM structure of the dimeric SPT-ORMDL3 complex
Descriptor: ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ...
Authors:Li, S.S, Xie, T, Wang, L, Gong, X.
Deposit date:2020-03-07
Release date:2021-02-10
Last modified:2021-03-24
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural insights into the assembly and substrate selectivity of human SPT-ORMDL3 complex.
Nat.Struct.Mol.Biol., 28, 2021
5WA4
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BU of 5wa4 by Molmil
Pyridine synthase, TbtD, from thiomuracin biosynthesis bound to an N-terminal leader peptide fragment
Descriptor: Pyridine synthase TbtD, TbtA 16-mer peptide
Authors:Cogan, D.P, Nair, S.K.
Deposit date:2017-06-24
Release date:2017-11-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.646 Å)
Cite:Structural insights into enzymatic [4+2] aza-cycloaddition in thiopeptide antibiotic biosynthesis.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W99
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BU of 5w99 by Molmil
Pyridine synthase, PbtD, from GE2270 biosynthesis bound to TSP
Descriptor: 2,2'-(6-(2'-(aminomethyl)-[2,4'-bithiazol]-4-yl)pyridine-2,5-diyl)bis(thiazole-4-carboxylic acid), PbtD, SULFATE ION
Authors:Cogan, D.P, Nair, S.K.
Deposit date:2017-06-22
Release date:2017-11-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Structural insights into enzymatic [4+2] aza-cycloaddition in thiopeptide antibiotic biosynthesis.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5WJP
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BU of 5wjp by Molmil
Crystal structure of the cyclohexadienyl dehydratase-like solute-binding protein SAR11_1068 from Candidatus Pelagibacter ubique.
Descriptor: Cyclohexadienyl dehydratase
Authors:Clifton, B.E, Jackson, C.J.
Deposit date:2017-07-24
Release date:2017-08-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Evolution of cyclohexadienyl dehydratase from an ancestral solute-binding protein.
Nat. Chem. Biol., 14, 2018
5WRB
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BU of 5wrb by Molmil
Crystal structure of hen egg-white lysozyme
Descriptor: CHLORIDE ION, Lysozyme C, SODIUM ION
Authors:Sugahara, M, Suzuki, M, Masuda, T, Inoue, S, Nango, E.
Deposit date:2016-12-01
Release date:2017-12-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.013 Å)
Cite:Hydroxyethyl cellulose matrix applied to serial crystallography
Sci Rep, 7, 2017

225681

數據於2024-10-02公開中

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