5IXE

1.75A RESOLUTION STRUCTURE OF 5-Fluoroindole BOUND BETA-GLYCOSIDASE (W33G) FROM SULFOLOBUS SOLFATARICUS

Summary for 5IXE

• Entry DOI: 10.2210/pdb5ixe/pdb
• Descriptor: Beta-galactosidase, 5-fluoro-1H-indole, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (5 entities in total)
• Functional Keywords: glycoside hydrolase, allosteric activation, switchable enzyme, chemical rescue, hydrolase
• Biological source: Sulfolobus solfataricus
• Total number of polymer chains: 2
• Total formula weight: 113861.63

Authors

Lovell, S.,Battaile, K.P.,Mehzabeen, N.,Budiardjo, S.J.,Karanicolas, J. (deposition date: 2016-03-23, release date: 2016-07-20, Last modification date: 2023-09-27)

• Primary citation: Budiardjo, S.J.,Licknack, T.J.,Cory, M.B.,Kapros, D.,Roy, A.,Lovell, S.,Douglas, J.,Karanicolas, J.; Full and Partial Agonism of a Designed Enzyme Switch.; ACS Synth Biol, 5:1475-1484, 2016; PubMed: 27389009; DOI: 10.1021/acssynbio.6b00097

Experimental method

X-RAY DIFFRACTION (1.75 Å)