6M4O

Cryo-EM structure of the monomeric SPT-ORMDL3 complex

Summary for 6M4O

• Entry DOI: 10.2210/pdb6m4o/pdb
• EMDB information: 30079 30080
• Descriptor: Serine palmitoyltransferase 1, Serine palmitoyltransferase 2, ORM1-like protein 3, ... (5 entities in total)
• Functional Keywords: membrane protein, lipid synthesis, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 197119.85

Authors

Li, S.S.,Xie, T.,Wang, L.,Gong, X. (deposition date: 2020-03-08, release date: 2021-02-10, Last modification date: 2021-03-24)

• Primary citation: Li, S.,Xie, T.,Liu, P.,Wang, L.,Gong, X.; Structural insights into the assembly and substrate selectivity of human SPT-ORMDL3 complex.; Nat.Struct.Mol.Biol., 28:249-257, 2021; PubMed: 33558762; DOI: 10.1038/s41594-020-00553-7

Experimental method

ELECTRON MICROSCOPY (3.4 Å)