5W99
Pyridine synthase, PbtD, from GE2270 biosynthesis bound to TSP
Summary for 5W99
Entry DOI | 10.2210/pdb5w99/pdb |
Descriptor | PbtD, 2,2'-(6-(2'-(aminomethyl)-[2,4'-bithiazol]-4-yl)pyridine-2,5-diyl)bis(thiazole-4-carboxylic acid), SULFATE ION, ... (4 entities in total) |
Functional Keywords | pyridine synthase, diels-alder, thiopeptide, biosynthetic protein |
Biological source | Planobispora rosea |
Total number of polymer chains | 1 |
Total formula weight | 38067.73 |
Authors | Cogan, D.P.,Nair, S.K. (deposition date: 2017-06-22, release date: 2017-11-22, Last modification date: 2023-10-04) |
Primary citation | Cogan, D.P.,Hudson, G.A.,Zhang, Z.,Pogorelov, T.V.,van der Donk, W.A.,Mitchell, D.A.,Nair, S.K. Structural insights into enzymatic [4+2] aza-cycloaddition in thiopeptide antibiotic biosynthesis. Proc. Natl. Acad. Sci. U.S.A., 114:12928-12933, 2017 Cited by PubMed: 29158402DOI: 10.1073/pnas.1716035114 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.59 Å) |
Structure validation
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