6HXL
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6HXP
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6HXN
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8DV1
| SARS-CoV-2 Wuhan-hu-1-Spike-RBD bound to linker variant of affinity matured ACE2 mimetic CVD432 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2,Immunoglobulin gamma-1 heavy chain fusion,Immunoglobulin gamma-1 heavy chain, Spike glycoprotein | Authors: | QCRG Structural Biology Consortium, Remesh, S.G, Merz, G.E, Brilot, A.F, Chio, U, Verba, K.A. | Deposit date: | 2022-07-27 | Release date: | 2022-08-31 | Last modified: | 2023-03-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps. Structure, 31, 2023
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8DV2
| SARS-CoV-2 Wuhan-hu-1-Spike-RBD bound to computationally engineered ACE2 mimetic CVD293 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2,Immunoglobulin gamma-1 heavy chain fusion, Spike glycoprotein | Authors: | QCRG Structural Biology Consortium, Remesh, S.G, Merz, G.E, Brilot, A.F, Chio, U, Verba, K.A. | Deposit date: | 2022-07-27 | Release date: | 2022-08-31 | Last modified: | 2023-03-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps. Structure, 31, 2023
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7RBV
| SARS-CoV-2 Spike in complex with PVI.V6-14 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PVI.V6-14 Fab heavy chain, ... | Authors: | Altomare, C.G, Bajic, G. | Deposit date: | 2021-07-06 | Release date: | 2022-05-04 | Last modified: | 2022-07-06 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure of a Vaccine-Induced, Germline-Encoded Human Antibody Defines a Neutralizing Epitope on the SARS-CoV-2 Spike N-Terminal Domain. Mbio, 13, 2022
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7RBU
| SARS-CoV-2 Spike in complex with PVI.V6-14 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PVI.V6-14 Fab heavy chain, ... | Authors: | Altomare, C.G, Bajic, G. | Deposit date: | 2021-07-06 | Release date: | 2022-05-04 | Last modified: | 2022-07-06 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structure of a Vaccine-Induced, Germline-Encoded Human Antibody Defines a Neutralizing Epitope on the SARS-CoV-2 Spike N-Terminal Domain. Mbio, 13, 2022
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6HXJ
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7KSB
| Crystal structure on Act c 10.0101 | Descriptor: | Non-specific lipid-transfer protein 1, SULFATE ION | Authors: | Pote, S, O'Malley, A, Gawlicka-Chruszcz, A, Giangrieco, I, Ciardiello, M.A, Chruszcz, M. | Deposit date: | 2020-11-21 | Release date: | 2021-01-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural Characterization of Act c 10.0101 and Pun g 1.0101-Allergens from the Non-Specific Lipid Transfer Protein Family. Molecules, 26, 2021
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6HXO
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7PHU
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7PI3
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7PHW
| PfCyRPA bound to monoclonal antibody Cy.004 Fab fragment | Descriptor: | CALCIUM ION, Cysteine-rich protective antigen, Monoclonal antibody Cy.004 heavy chain, ... | Authors: | Ragotte, R.J, Higgins, M.K. | Deposit date: | 2021-08-18 | Release date: | 2022-02-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.793 Å) | Cite: | Heterotypic interactions drive antibody synergy against a malaria vaccine candidate. Nat Commun, 13, 2022
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7PI7
| PfCyRPA bound to monoclonal antibody Cy.002 Fab fragment | Descriptor: | Cysteine-rich protective antigen, Monoclonal antibody Cy.002 heavy chain, Monoclonal antibody Cy.002 light chain | Authors: | Ragotte, R.J, Higgins, M.K. | Deposit date: | 2021-08-19 | Release date: | 2022-02-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Heterotypic interactions drive antibody synergy against a malaria vaccine candidate. Nat Commun, 13, 2022
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7PHV
| PfCyRPA bound to monoclonal antibody Cy.007 Fab fragment | Descriptor: | AMMONIUM ION, Cysteine-rich protective antigen, Monoclonal antibody Cy.007 heavy chain, ... | Authors: | Ragotte, R.J, Higgins, M.K. | Deposit date: | 2021-08-18 | Release date: | 2022-02-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.091 Å) | Cite: | Heterotypic interactions drive antibody synergy against a malaria vaccine candidate. Nat Commun, 13, 2022
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7PI2
| PfCyRPA bound to monoclonal antibody Cy.003 Fab fragment | Descriptor: | Cysteine-rich protective antigen, Monoclonal antibody Cy.003 heavy chain, Monoclonal antibody Cy.003 light chain | Authors: | Ragotte, R.J, Higgins, M.K. | Deposit date: | 2021-08-19 | Release date: | 2022-02-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.14 Å) | Cite: | Heterotypic interactions drive antibody synergy against a malaria vaccine candidate. Nat Commun, 13, 2022
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8HDU
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8HDV
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5AP9
| Controlled lid-opening in Thermomyces lanuginosus lipase - a switch for activity and binding | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Skjold-Joergensen, J, Vind, J, Moroz, O.V, Blagova, E.V, Bhatia, V.K, Svendsen, A, Wilson, K.S, Bjerrum, M.J. | Deposit date: | 2015-09-15 | Release date: | 2016-09-28 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Controlled lid-opening in Thermomyces lanuginosus lipase- An engineered switch for studying lipase function. Biochim. Biophys. Acta, 1865, 2017
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6KSH
| Crystal structure of pyruvate kinase (PYK) from Plasmodium falciparum in complex with oxalate and ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, OXALATE ION, ... | Authors: | Zhong, W, Cai, Q, Li, K, Lescar, J, Dedon, P.C. | Deposit date: | 2019-08-23 | Release date: | 2020-08-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Pyruvate kinase from Plasmodium falciparum: Structural and kinetic insights into the allosteric mechanism. Biochem.Biophys.Res.Commun., 532, 2020
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7AA5
| Human TRPV4 structure in presence of 4a-PDD | Descriptor: | CALCIUM ION, Transient receptor potential cation channel subfamily V member 4,Green fluorescent protein | Authors: | Botte, M, Ulrich, A.K.G, Adaixo, R, Gnutt, D, Brockmann, A, Bucher, D, Chami, M, Bocquet, M, Ebbinghaus-Kintscher, U, Puetter, V, Becker, A, Egner, U, Stahlberg, H, Hennig, M, Holton, S.J. | Deposit date: | 2020-09-03 | Release date: | 2021-08-18 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (4.18 Å) | Cite: | Cryo-EM structural studies of the agonist complexed human TRPV4 ion-channel reveals novel structural rearrangements resulting in an open-conformation To Be Published
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7PTV
| Structure of the Mimivirus genomic fibre asymmetric unit | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Putative glucose-methanol-choline oxidoreductase protein | Authors: | Villalta, A, Schmitt, A, Estrozi, L.F, Quemin, E.R.J, Alempic, J.M, Lartigue, A, Prazak, V, Belmudes, L, Vasishtan, D, Colmant, A.M.G, Honore, F.A, Coute, Y, Grunewald, K, Abergel, C. | Deposit date: | 2021-09-27 | Release date: | 2022-08-10 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | The giant mimivirus 1.2 Mb genome is elegantly organized into a 30 nm diameter helical protein shield. Elife, 11, 2022
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5CBX
| AncGR DNA Binding Domain - (+)GRE Complex | Descriptor: | AncGR DNA Binding Domain, DNA (5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*GP*AP*GP*TP*GP*TP*TP*CP*TP*G)-3'), DNA (5'-D(*TP*CP*AP*GP*AP*AP*CP*AP*CP*TP*CP*TP*GP*TP*TP*CP*TP*G)-3'), ... | Authors: | Hudson, W.H, Ortlund, E.A. | Deposit date: | 2015-07-01 | Release date: | 2015-12-23 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Distal substitutions drive divergent DNA specificity among paralogous transcription factors through subdivision of conformational space. Proc.Natl.Acad.Sci.USA, 113, 2016
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5CC1
| S425G Glucocorticoid receptor DNA binding domain - (+)GRE complex | Descriptor: | DNA (5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*GP*AP*GP*TP*GP*TP*TP*CP*TP*G)-3'), DNA (5'-D(*TP*CP*AP*GP*AP*AP*CP*AP*CP*TP*CP*TP*GP*TP*TP*CP*TP*G)-3'), Glucocorticoid receptor, ... | Authors: | Hudson, W.H, Weikum, E.A, Ortlund, E.A. | Deposit date: | 2015-07-01 | Release date: | 2015-12-23 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.302 Å) | Cite: | Distal substitutions drive divergent DNA specificity among paralogous transcription factors through subdivision of conformational space. Proc.Natl.Acad.Sci.USA, 113, 2016
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8EKD
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