5CC1

S425G Glucocorticoid receptor DNA binding domain - (+)GRE complex

Summary for 5CC1

• Entry DOI: 10.2210/pdb5cc1/pdb
• Descriptor: Glucocorticoid receptor, DNA (5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*GP*AP*GP*TP*GP*TP*TP*CP*TP*G)-3'), DNA (5'-D(*TP*CP*AP*GP*AP*AP*CP*AP*CP*TP*CP*TP*GP*TP*TP*CP*TP*G)-3'), ... (5 entities in total)
• Functional Keywords: dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 73456.70

Authors

Hudson, W.H.,Weikum, E.A.,Ortlund, E.A. (deposition date: 2015-07-01, release date: 2015-12-23, Last modification date: 2024-03-06)

• Primary citation: Hudson, W.H.,Kossmann, B.R.,de Vera, I.M.,Chuo, S.W.,Weikum, E.R.,Eick, G.N.,Thornton, J.W.,Ivanov, I.N.,Kojetin, D.J.,Ortlund, E.A.; Distal substitutions drive divergent DNA specificity among paralogous transcription factors through subdivision of conformational space.; Proc.Natl.Acad.Sci.USA, 113:326-331, 2016; PubMed: 26715749; DOI: 10.1073/pnas.1518960113

Experimental method

X-RAY DIFFRACTION (2.302 Å)