5CC1
S425G Glucocorticoid receptor DNA binding domain - (+)GRE complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0043565 | molecular_function | sequence-specific DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0043565 | molecular_function | sequence-specific DNA binding |
| W | 0003700 | molecular_function | DNA-binding transcription factor activity |
| W | 0006355 | biological_process | regulation of DNA-templated transcription |
| W | 0008270 | molecular_function | zinc ion binding |
| W | 0043565 | molecular_function | sequence-specific DNA binding |
| X | 0003700 | molecular_function | DNA-binding transcription factor activity |
| X | 0006355 | biological_process | regulation of DNA-templated transcription |
| X | 0008270 | molecular_function | zinc ion binding |
| X | 0043565 | molecular_function | sequence-specific DNA binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 601 |
| Chain | Residue |
| A | CYS421 |
| A | CYS424 |
| A | CYS438 |
| A | CYS441 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 602 |
| Chain | Residue |
| A | CYS457 |
| A | CYS463 |
| A | CYS473 |
| A | CYS476 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 601 |
| Chain | Residue |
| B | CYS424 |
| B | CYS438 |
| B | CYS441 |
| B | CYS421 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 602 |
| Chain | Residue |
| B | CYS457 |
| B | CYS463 |
| B | CYS473 |
| B | CYS476 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue ZN W 601 |
| Chain | Residue |
| W | CYS421 |
| W | CYS424 |
| W | CYS438 |
| W | CYS441 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN W 602 |
| Chain | Residue |
| W | CYS457 |
| W | CYS463 |
| W | CYS473 |
| W | CYS476 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue ZN X 601 |
| Chain | Residue |
| X | CYS421 |
| X | CYS424 |
| X | CYS438 |
| X | CYS441 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue ZN X 602 |
| Chain | Residue |
| X | CYS457 |
| X | CYS463 |
| X | CYS473 |
| X | CYS476 |
Functional Information from PROSITE/UniProt
| site_id | PS00031 |
| Number of Residues | 27 |
| Details | NUCLEAR_REC_DBD_1 Nuclear hormones receptors DNA-binding region signature. ClvCg.Deasgc.HYgvltCgsCkvFFkR |
| Chain | Residue | Details |
| A | CYS421-ARG447 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 156 |
| Details | Zinc finger: {"description":"NR C4-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00407","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19141540","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"UniProtKB","id":"P06537","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
