PDB: 1544 resultsInfo pagesStatus searchChemie searchBIRD

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3VUW	Crystal structure of A20 ZF7 in complex with linear ubiquitin, form I Descriptor: POTASSIUM ION, Polyubiquitin-C, Tumor necrosis factor alpha-induced protein 3, ... Authors: Nishimasu, H, Ishitani, R, Nureki, O. Deposit date: 2012-07-09 Release date: 2013-02-13 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-kappaB regulation Embo J., 31, 2012
3VAW	Crystal structure of a smt fusion peptidyl-prolyl cis-trans isomerase with surface mutation v3i from burkholderia pseudomallei complexed with fk506 Descriptor: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, Ubiquitin-like protein SMT3,Peptidyl-prolyl cis-trans isomerase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2011-12-29 Release date: 2012-01-18 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.55 Å) Cite: A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins. Antimicrob.Agents Chemother., 58, 2014
2HD5	USP2 in complex with ubiquitin Descriptor: Polyubiquitin, Ubiquitin carboxyl-terminal hydrolase 2, ZINC ION Authors: Renatus, M, Kroemer, M. Deposit date: 2006-06-20 Release date: 2006-08-15 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structural Basis of Ubiquitin Recognition by the Deubiquitinating Protease USP2. Structure, 14, 2006
3V62	Structure of the S. cerevisiae Srs2 C-terminal domain in complex with PCNA conjugated to SUMO on lysine 164 Descriptor: ATP-dependent DNA helicase SRS2, N-ETHYLMALEIMIDE, Proliferating cell nuclear antigen, ... Authors: Armstrong, A.A, Mohideen, F, Lima, C.D. Deposit date: 2011-12-18 Release date: 2012-02-29 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2. Nature, 483, 2012
2G3Q	Solution Structure of Ede1 UBA-ubiquitin complex Descriptor: Protein YBL047C, Ubiquitin Authors: Swanson, K.A, Hicke, L, Radhakrishnan, I. Deposit date: 2006-02-20 Release date: 2006-05-09 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Structural Basis for Monoubiquitin Recognition by the Ede1 UBA Domain. J.Mol.Biol., 358, 2006
2G45	Co-crystal structure of znf ubp domain from the deubiquitinating enzyme isopeptidase T (isot) in complex with ubiquitin Descriptor: CHLORIDE ION, Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 5, ... Authors: Reyes-Turcu, F.E, Horton, J.R, Mullally, J.E, Heroux, A, Cheng, X, Wilkinson, K.D. Deposit date: 2006-02-21 Release date: 2006-04-04 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.99 Å) Cite: The Ubiquitin Binding Domain ZnF UBP Recognizes the C-Terminal Diglycine Motif of Unanchored Ubiquitin. Cell(Cambridge,Mass.), 124, 2006
3TIX	Crystal structure of the Chp1-Tas3 complex core Descriptor: CHLORIDE ION, Chromo domain-containing protein 1, POTASSIUM ION, ... Authors: Schalch, T, Joshua-Tor, L. Deposit date: 2011-08-22 Release date: 2011-11-16 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.9001 Å) Cite: The Chp1-Tas3 core is a multifunctional platform critical for gene silencing by RITS. Nat.Struct.Mol.Biol., 18, 2011
3VUX	Crystal structure of A20 ZF7 in complex with linear ubiquitin, form II Descriptor: 1,2-ETHANEDIOL, POTASSIUM ION, Polyubiquitin-C, ... Authors: Nishimasu, H, Ishitani, R, Nureki, O. Deposit date: 2012-07-09 Release date: 2013-02-13 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.699 Å) Cite: Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-kappaB regulation Embo J., 31, 2012
3VUY	Crystal structure of A20 ZF7 in complex with linear tetraubiquitin Descriptor: POTASSIUM ION, Polyubiquitin-C, Tumor necrosis factor alpha-induced protein 3, ... Authors: Nishimasu, H, Ishitani, R, Nureki, O. Deposit date: 2012-07-09 Release date: 2013-02-13 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.981 Å) Cite: Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-kappaB regulation Embo J., 31, 2012
3UF8	Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase with a G95A surface mutation from Burkholderia pseudomallei complexed with FK506 Descriptor: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, Ubiquitin-like protein SMT3, Peptidyl-prolyl cis-trans isomerase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2011-10-31 Release date: 2011-11-09 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.5 Å) Cite: A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins. Antimicrob.Agents Chemother., 58, 2014
3TMP	The catalytic domain of human deubiquitinase DUBA in complex with ubiquitin aldehyde Descriptor: OTU domain-containing protein 5, Polyubiquitin-C Authors: Ma, X, Yin, J, Hymowitz, S, Starovasnik, M, Cochran, A. Deposit date: 2011-08-31 Release date: 2012-01-11 Last modified: 2012-02-29 Method: X-RAY DIFFRACTION (1.91 Å) Cite: Phosphorylation-dependent activity of the deubiquitinase DUBA. Nat.Struct.Mol.Biol., 19, 2012
3WXG	Crystal structure of CYLD USP domain (C596A) in complex with Lys63-linked diubiquitin Descriptor: Ubiquitin, Uncharacterized protein Authors: Sato, Y, Fukai, S. Deposit date: 2014-07-30 Release date: 2015-02-11 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structures of CYLD USP with Met1- or Lys63-linked diubiquitin reveal mechanisms for dual specificity. Nat.Struct.Mol.Biol., 22, 2015
3WXE	Crystal structure of CYLD USP domain (C596S) in complex with Met1-linked diubiquitin Descriptor: Ubiquitin, Uncharacterized protein Authors: Sato, Y, Fukai, S. Deposit date: 2014-07-30 Release date: 2015-02-11 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structures of CYLD USP with Met1- or Lys63-linked diubiquitin reveal mechanisms for dual specificity. Nat.Struct.Mol.Biol., 22, 2015
2HTH	Structural basis for ubiquitin recognition by the human EAP45/ESCRT-II GLUE domain Descriptor: Ubiquitin, Vacuolar protein sorting protein 36 Authors: Alam, S.L, Whitby, F.G, Hill, C.P, Sundquist, W.I. Deposit date: 2006-07-25 Release date: 2006-10-24 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural basis for ubiquitin recognition by the human ESCRT-II EAP45 GLUE domain. Nat.Struct.Mol.Biol., 13, 2006
3WWQ	Crystal structure of FAAP20 UBZ domain in complex with Lys63-linked diubiquitin Descriptor: Fanconi anemia-associated protein of 20 kDa, Ubiquitin, ZINC ION Authors: Sato, Y, Fukai, S. Deposit date: 2014-06-23 Release date: 2015-05-13 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural Basis for Ubiquitin Recognition by Ubiquitin-Binding Zinc Finger of FAAP20 Plos One, 10, 2015
2IBI	Covalent Ubiquitin-USP2 Complex Descriptor: ETHANAMINE, Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 2, ... Authors: Walker, J.R, Avvakumov, G.V, Bernstein, G, Xue, S, Finerty Jr, P.J, MacKenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) Deposit date: 2006-09-11 Release date: 2006-10-24 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Covalent Ubiquitin-USP2 Complex To be Published
5ZBI	Crystal structure of asparaginyl endopeptidases from Viola Canadensis Descriptor: Peptide asparaginyl ligase, SODIUM ION Authors: Wong, Y.H, Lescar, J. Deposit date: 2018-02-12 Release date: 2018-05-09 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.09 Å) Cite: Crystal structure of Peptide asparaginyl ligase from Viola canadensis To Be Published
5ZQ6	SidE-Ubi-ADPr Descriptor: ADENOSINE-5'-DIPHOSPHATE, SidE, Ubiquitin Authors: Wang, Y, Gao, A, Gao, P. Deposit date: 2018-04-17 Release date: 2018-05-23 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.009 Å) Cite: Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE. Cell, 173, 2018
9BOL	Crystal structure of the complex between VHL, ElonginB, ElonginC, and compound 5 Descriptor: (4R)-1-[(2S)-2-(4-cyclopropyl-1H-1,2,3-triazol-1-yl)-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}-L-prolinamide, 1,2-ETHANEDIOL, CHLORIDE ION, ... Authors: Murray, J.M, Wu, H, Fuhrmann, J, Fairbrother, W.J, DiPasquale, A. Deposit date: 2024-05-03 Release date: 2024-05-29 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Potency-enhanced peptidomimetic VHL ligands with improved oral bioavailability To Be Published
6A43	R1EN(5-225)-ubiquitin fusion Descriptor: ACETIC ACID, RNA-directed DNA polymerase homolog (R1),Polyubiquitin-C Authors: Maita, N. Deposit date: 2018-06-19 Release date: 2018-10-24 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal Structure Determination of Ubiquitin by Fusion to a Protein That Forms a Highly Porous Crystal Lattice J. Am. Chem. Soc., 140, 2018
4HXD	Diversity of ubiquitin and ISG15 specificity amongst nairoviruses viral ovarian tumor domain proteases Descriptor: 1.7.6 3-bromanylpropan-1-amine, Polyubiquitin-C, RNA-directed RNA polymerase L, ... Authors: Capodagli, G.C, Pegan, S.D. Deposit date: 2012-11-09 Release date: 2013-02-13 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Diversity of Ubiquitin and ISG15 Specificity among Nairoviruses' Viral Ovarian Tumor Domain Proteases. J.Virol., 87, 2013
6A44	R1EN(5-227)-ubiquitin fusion Descriptor: ACETIC ACID, RNA-directed DNA polymerase homolog (R1),Polyubiquitin-C Authors: Maita, N. Deposit date: 2018-06-19 Release date: 2018-10-24 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal Structure Determination of Ubiquitin by Fusion to a Protein That Forms a Highly Porous Crystal Lattice J. Am. Chem. Soc., 140, 2018
9BJU	Crystal structure of the complex between VHL, ElonginB, ElonginC, and compound 5 Descriptor: 1,2-ETHANEDIOL, 3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE, ACETATE ION, ... Authors: Murray, J.M, Wu, H, Fuhrmann, J, Fairbrother, W.J, DiPasquale, A. Deposit date: 2024-04-25 Release date: 2024-05-29 Method: X-RAY DIFFRACTION (2.47 Å) Cite: Potency-enhanced peptidomimetic VHL ligands with improved oral bioavailability To Be Published
5C7M	CRYSTAL STRUCTURE OF E3 LIGASE ITCH WITH A UB VARIANT Descriptor: E3 ubiquitin-protein ligase Itchy homolog, Polyubiquitin-C Authors: Walker, J.R, Hu, J, Dong, A, Wernimont, A, Zhang, W, Sidhu, S, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC) Deposit date: 2015-06-24 Release date: 2016-03-16 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.03 Å) Cite: System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. Mol.Cell, 62, 2016
5C23	Parkin (S65DUblR0RBR) Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase parkin, GLYCEROL, ... Authors: Kumar, A, Aguirre, J.D, Condos, T.E.C, Martinez-Torres, R.J, Chaugule, V.K, Toth, R, Sundaramoorthy, R, Mercier, P, Knebel, A, Spratt, D.E, Barber, K.R, Shaw, G.S, Walden, H. Deposit date: 2015-06-15 Release date: 2015-07-29 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.37 Å) Cite: Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis. Embo J., 34, 2015

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