PDB: 39 resultsInfo pagesStatus searchChemie searchBIRD

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7TDW	Structure of FOXP3-DNA complex Descriptor: DNA (5'-D(*AP*AP*AP*TP*TP*TP*GP*TP*TP*TP*AP*CP*TP*C)-3'), DNA (5'-D(P*GP*AP*GP*TP*AP*AP*AP*CP*AP*AP*AP*TP*TP*T)-3'), Forkhead box P3 Authors: Leng, F, Hur, S. Deposit date: 2022-01-03 Release date: 2022-08-10 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (4 Å) Cite: The transcription factor FoxP3 can fold into two dimerization states with divergent implications for regulatory T cell function and immune homeostasis. Immunity, 55, 2022
5T1J	Crystal Structure of the Tbox DNA binding domain of the transcription factor T-bet Descriptor: DNA, T-box transcription factor TBX21 Authors: Liu, C.F, Brandt, G.S, Hoang, Q, Hwang, E.S, Naumova, N, Lazarevic, V, Dekker, J, Glimcher, L.H, Ringe, D, Petsko, G.A. Deposit date: 2016-08-19 Release date: 2016-10-26 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.947 Å) Cite: Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites. Proc.Natl.Acad.Sci.USA, 113, 2016
3WTZ	Crystal structure of ETS-1 DNA binding and autoinhibitory domains (276-441) Descriptor: Protein C-ets-1 Authors: Shiina, M, Hamada, K, Ogata, K. Deposit date: 2014-04-21 Release date: 2014-08-20 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.61 Å) Cite: A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427, 2015
1E50	AML1/CBFbeta complex Descriptor: CORE-BINDING FACTOR ALPHA SUBUNIT, CORE-BINDING FACTOR CBF-BETA Authors: Warren, A.J, Bravo, J, Williams, R.L, Rabbits, T.H. Deposit date: 2000-07-13 Release date: 2001-07-12 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural Basis for the Heterodimeric Interaction between the Acute Leukaemia-Associated Transcription Factors Aml1 and Cbfbeta Embo J., 19, 2000
6LH4	Crystal structural of MacroD1-ADPr complex Descriptor: ADP-ribose glycohydrolase MACROD1, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE Authors: Yang, X, Ma, Y, Li, Y. Deposit date: 2019-12-06 Release date: 2020-12-09 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.999 Å) Cite: Molecular basis for the MacroD1-mediated hydrolysis of ADP-ribosylation. DNA Repair (Amst), 94, 2020
2X47	Crystal structure of human MACROD1 Descriptor: MACRO DOMAIN-CONTAINING PROTEIN 1, SULFATE ION Authors: Vollmar, M, Phillips, C, Mehrotra, P.V, Ahel, I, Krojer, T, Yue, W, Ugochukwu, E, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Gileadi, O. Deposit date: 2010-01-28 Release date: 2010-03-02 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Identification of Macro Domain Proteins as Novel O-Acetyl-Adp-Ribose Deacetylases. J.Biol.Chem., 286, 2011
3RI4	Ets1 cooperative binding to widely separated sites on promoter DNA Descriptor: Isoform Ets-1 p27 of Protein C-ets-1, TCR alpha promoter DNA Authors: Babayeva, N.D, Mino, K, Tahirov, T.H. Deposit date: 2011-04-12 Release date: 2012-04-04 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural basis of ets1 cooperative binding to widely separated sites on promoter DNA. Plos One, 7, 2012
2RRC	Solution Structure of RNA aptamer against AML1 Runt domain Descriptor: 5'-R(P*GP*GP*AP*CP*CP*CP*(AP7)P*CP*CP*AP*CP*GP*GP*CP*GP*AP*GP*GP*UP*CP*CP*A)-3' Authors: Nomura, Y, Fujiwara, K, Chiba, M, Fukunaga, J, Tanaka, Y, Iibuchi, H, Tanaka, T, Nakamura, Y, Kawai, G, Kozu, T, Sakamoto, T. Deposit date: 2010-06-23 Release date: 2011-06-29 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: A novel high affinity RNA motif that mimics DNA in AML1 Runt domain binding To be Published
1MD0	CRYSTAL STRUCTURE OF AN INHIBITED FRAGMENT OF Ets-1 Descriptor: C-ets-1 protein Authors: Garvie, C.W, Pufall, M.A, Graves, B.J, Wolberger, C. Deposit date: 2002-08-06 Release date: 2002-12-11 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural Analysis of the Autoinhibition of Ets-1 and Its Role in Protein Partnerships J.Biol.Chem., 277, 2002
1MDM	INHIBITED FRAGMENT OF ETS-1 AND PAIRED DOMAIN OF PAX5 BOUND TO DNA Descriptor: C-ETS-1 PROTEIN, PAIRED BOX PROTEIN PAX-5, PAX5/ETS BINDING SITE ON THE MB-1 PROMOTER Authors: Garvie, C.W, Pufall, M.A, Graves, B.J, Wolberger, C. Deposit date: 2002-08-07 Release date: 2002-12-11 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.8 Å) Cite: STRUCTURAL ANALYSIS OF THE AUTOINHIBITION OF ETS-1 AND ITS ROLE IN PROTEIN PARTNERSHIPS J.Biol.Chem., 277, 2002
2DJ8	Solution Structure of zf-MYND Domain of Protein CBFA2TI (Protein MTG8) Descriptor: Protein CBFA2T1, ZINC ION Authors: Niraula, T.N, Sasagawa, A, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2006-03-31 Release date: 2006-10-01 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution Structure of zf-MYND Domain of Protein CBFA2TI (Protein MTG8) To be published
2KNH	The Solution structure of the eTAFH domain of AML1-ETO complexed with HEB peptide Descriptor: Protein CBFA2T1, Transcription factor 12 Authors: Park, S, Cierpicki, T, Tonelli, M, Bushweller, J.H. Deposit date: 2009-08-25 Release date: 2009-10-06 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Structure of the AML1-ETO eTAFH domain-HEB peptide complex and its contribution to AML1-ETO activity. Blood, 113, 2009
2KYG	Structure of the AML1-ETO Nervy Domain - PKA(RIIa) complex and its contribution to AML1-ETO activity Descriptor: Protein CBFA2T1, cAMP-dependent protein kinase type II-alpha regulatory subunit Authors: Corpora, T.A, Cierpecki, T, Bushweller, J. Deposit date: 2010-05-25 Release date: 2010-10-20 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Structure of the AML1-ETO NHR3-PKA(RIIalpha) complex and its contribution to AML1-ETO activity. J.Mol.Biol., 402, 2010
4JOL	Complex structure of AML1-ETO NHR2 domain with HEB fragment Descriptor: Protein CBFA2T1, Transcription factor 12 Authors: Wang, Z, Patel, D.J. Deposit date: 2013-03-18 Release date: 2013-06-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.906 Å) Cite: A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis. Nature, 500, 2013

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