2RRC

Solution Structure of RNA aptamer against AML1 Runt domain

Summary for 2RRC

• Entry DOI: 10.2210/pdb2rrc/pdb
• NMR Information: BMRB: 11176
• Descriptor: 5'-R(P*GP*GP*AP*CP*CP*CP*(AP7)P*CP*CP*AP*CP*GP*GP*CP*GP*AP*GP*GP*UP*CP*CP*A)-3' (1 entity in total)
• Functional Keywords: rna aptamer, aml1/runx1, molecular mimicry, rna
• Total number of polymer chains: 1
• Total formula weight: 7071.32

Authors

Nomura, Y.,Fujiwara, K.,Chiba, M.,Fukunaga, J.,Tanaka, Y.,Iibuchi, H.,Tanaka, T.,Nakamura, Y.,Kawai, G.,Kozu, T.,Sakamoto, T. (deposition date: 2010-06-23, release date: 2011-06-29, Last modification date: 2020-02-26)

• Primary citation: Nomura, Y.,Fukunaga, J.,Tanaka, Y.,Fujiwara, K.,Chiba, M.,Iibuchi, H.,Tanaka, T.,Nakamura, Y.,Kawai, G.,Sakamoto, T.,Kozu, T.; A novel high affinity RNA motif that mimics DNA in AML1 Runt domain binding; To be Published,

Experimental method

SOLUTION NMR