2KYG

Structure of the AML1-ETO Nervy Domain - PKA(RIIa) complex and its contribution to AML1-ETO activity

Summary for 2KYG

• Entry DOI: 10.2210/pdb2kyg/pdb
• NMR Information: BMRB: 16954
• Descriptor: cAMP-dependent protein kinase type II-alpha regulatory subunit, Protein CBFA2T1 (2 entities in total)
• Functional Keywords: protein/protein, homodimer bound to monomer, protein binding
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 15427.57

Authors

Corpora, T.A.,Cierpecki, T.,Bushweller, J. (deposition date: 2010-05-25, release date: 2010-10-20, Last modification date: 2024-05-15)

• Primary citation: Corpora, T.,Roudaia, L.,Oo, Z.M.,Chen, W.,Manuylova, E.,Cai, X.,Chen, M.J.,Cierpicki, T.,Speck, N.A.,Bushweller, J.H.; Structure of the AML1-ETO NHR3-PKA(RIIalpha) complex and its contribution to AML1-ETO activity.; J.Mol.Biol., 402:560-577, 2010; PubMed: 20708017; DOI: 10.1016/j.jmb.2010.08.007

Experimental method

SOLUTION NMR