2KYG
Structure of the AML1-ETO Nervy Domain - PKA(RIIa) complex and its contribution to AML1-ETO activity
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | cAMP-dependent protein kinase type II-alpha regulatory subunit | polymer | 50 | 5621.4 | 2 | UniProt (P13861) Pfam (PF02197) | Homo sapiens (human) | |
| 2 | C (C) | Protein CBFA2T1 | polymer | 38 | 4184.7 | 1 | UniProt (Q06455) | Homo sapiens (human) | Protein MTG8, Protein ETO, Eight twenty one protein, Cyclin-D-related protein, Zinc finger MYND domain-containing protein 2 |
Sequence modifications
A, B: -2 - 44 (UniProt: P13861)
C: 585 - 615 (UniProt: Q06455)
| PDB | External Database | Details |
|---|---|---|
| Gly -7 | - | expression tag |
| Ala -6 | - | expression tag |
| Met -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 578 | - | expression tag |
| Met 579 | - | expression tag |
| Ala 580 | - | expression tag |
| Asp 581 | - | expression tag |
| Ile 582 | - | expression tag |
| Gly 583 | - | expression tag |
| Ser 584 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 15427.6 | |
| All* | Total formula weight | 15427.6 |
