6LH4

Crystal structural of MacroD1-ADPr complex

Summary for 6LH4

• Entry DOI: 10.2210/pdb6lh4/pdb
• Descriptor: ADP-ribose glycohydrolase MACROD1, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE (3 entities in total)
• Functional Keywords: macrod1, adpr, catalysis, dna repair, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 107679.22

Authors

Yang, X.,Ma, Y.,Li, Y. (deposition date: 2019-12-06, release date: 2020-12-09, Last modification date: 2023-11-29)

• Primary citation: Yang, X.,Ma, Y.,Li, Y.,Dong, Y.,Yu, L.L.,Wang, H.,Guo, L.,Wu, C.,Yu, X.,Liu, X.; Molecular basis for the MacroD1-mediated hydrolysis of ADP-ribosylation.; DNA Repair (Amst), 94:102899-102899, 2020; PubMed: 32683309; DOI: 10.1016/j.dnarep.2020.102899

Experimental method

X-RAY DIFFRACTION (1.999 Å)