5T1J

Crystal Structure of the Tbox DNA binding domain of the transcription factor T-bet

Summary for 5T1J

• Entry DOI: 10.2210/pdb5t1j/pdb
• Descriptor: T-box transcription factor TBX21, DNA (2 entities in total)
• Functional Keywords: t-bet, tbox, tbx21, dna looping, transcriptional regulation, master regulator, transcription factor, dna binding, transcription-dna complex, transcription/dna
• Biological source: Mus musculus (Mouse); More
• Cellular location: Nucleus: Q9JKD8
• Total number of polymer chains: 6
• Total formula weight: 76372.23

Authors

Liu, C.F.,Brandt, G.S.,Hoang, Q.,Hwang, E.S.,Naumova, N.,Lazarevic, V.,Dekker, J.,Glimcher, L.H.,Ringe, D.,Petsko, G.A. (deposition date: 2016-08-19, release date: 2016-10-26, Last modification date: 2023-12-27)

• Primary citation: Liu, C.F.,Brandt, G.S.,Hoang, Q.Q.,Naumova, N.,Lazarevic, V.,Hwang, E.S.,Dekker, J.,Glimcher, L.H.,Ringe, D.,Petsko, G.A.; Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites.; Proc.Natl.Acad.Sci.USA, 113:E6572-E6581, 2016; PubMed: 27791029; DOI: 10.1073/pnas.1613914113

Experimental method

X-RAY DIFFRACTION (2.947 Å)