PDB: 57 resultsInfo pagesStatus searchChemie searchBIRD

---

3MHZ	1.7A structure of 2-fluorohistidine labeled Protective Antigen Descriptor: CALCIUM ION, Protective antigen, TETRAETHYLENE GLYCOL Authors: Lovell, S, Battaile, K.P, Wimalasena, D.S, Janowiak, B.E, Miyagi, M, Sun, J, Hajduch, J, Pooput, C, Kirk, K.L, Bann, J.G. Deposit date: 2010-04-09 Release date: 2010-08-11 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Evidence that histidine protonation of receptor-bound anthrax protective antigen is a trigger for pore formation. Biochemistry, 49, 2010
3KWV	Structural basis for the unfolding of anthrax lethal factor by protective antigen oligomers Descriptor: CALCIUM ION, Lethal factor, Protective antigen PA-63 Authors: Feld, G.K, Kintzer, A.F, Krantz, B.A. Deposit date: 2009-12-01 Release date: 2010-11-10 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (3.101 Å) Cite: Structural basis for the unfolding of anthrax lethal factor by protective antigen oligomers. Nat.Struct.Mol.Biol., 17, 2010
3TEW	Crystal Structure of Anthrax Protective Antigen (Membrane Insertion Loop Deleted) to 1.45-A resolution Descriptor: 2-METHOXYETHANOL, CALCIUM ION, Protective antigen Authors: Feld, G.K, Krantz, B.A. Deposit date: 2011-08-15 Release date: 2011-10-26 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Domain flexibility modulates the heterogeneous assembly mechanism of anthrax toxin protective antigen. J.Mol.Biol., 415, 2012
3TEX	Crystal Structure of Anthrax Protective Antigen (Membrane Insertion Loop Deleted) to 1.7-A resolution Descriptor: CALCIUM ION, Protective antigen Authors: Feld, G.K, Krantz, B.A. Deposit date: 2011-08-15 Release date: 2011-10-26 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Domain flexibility modulates the heterogeneous assembly mechanism of anthrax toxin protective antigen. J.Mol.Biol., 415, 2012
3TEZ	Crystal Structure of Anthrax Protective Antigen Mutant S337C N664C and dithiolacetone modified to 1.8-A resolution Descriptor: 2-METHOXYETHANOL, ACETONE, CALCIUM ION, ... Authors: Feld, G.K, Krantz, B.A. Deposit date: 2011-08-15 Release date: 2011-10-26 Last modified: 2012-05-23 Method: X-RAY DIFFRACTION (1.83 Å) Cite: Domain flexibility modulates the heterogeneous assembly mechanism of anthrax toxin protective antigen. J.Mol.Biol., 415, 2012
3TEY	Crystal Structure of Anthrax Protective Antigen (Membrane Insertion Loop Deleted) Mutant S337C N664C to 2.06-A resolution Descriptor: CALCIUM ION, Protective antigen Authors: Feld, G.K, Krantz, B.A. Deposit date: 2011-08-15 Release date: 2011-10-26 Last modified: 2012-05-23 Method: X-RAY DIFFRACTION (2.12 Å) Cite: Domain flexibility modulates the heterogeneous assembly mechanism of anthrax toxin protective antigen. J.Mol.Biol., 415, 2012
8DCM	Crystal structure of Clostridioides difficile binary toxin proCDTb lacking D4 in complex with BINTOXB/22 Fab Descriptor: ADP-ribosylating binary toxin binding subunit CdtB, BINTOXB/22 Fab heavy chain, BINTOXB/22 Fab light chain, ... Authors: Goldsmith, J.A, McLellan, J.S. Deposit date: 2022-06-16 Release date: 2023-04-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural Basis for Binding of Neutralizing Antibodies to Clostridioides difficile Binary Toxin. J.Bacteriol., 205, 2023
8EKM	Clostridioides difficile binary toxin translocase CDTb double mutant - D623A D734A Descriptor: ADP-ribosyltransferase binding component, CALCIUM ION Authors: Abeyawardhane, D.L, Pozharski, E. Deposit date: 2022-09-21 Release date: 2023-09-27 Method: ELECTRON MICROSCOPY (3.56 Å) Cite: Calcium-mediated Pore Formation of Clostridioides difficile Binary Toxin To Be Published
8EKK	Clostridioides difficile binary toxin translocase CDTb wild-type after calcium depletion from receptor binding domain 1 (RBD1) - Class 2 Descriptor: ADP-ribosyltransferase binding component, CALCIUM ION Authors: Abeyawardhane, D.L, Pozharski, E. Deposit date: 2022-09-21 Release date: 2023-09-27 Method: ELECTRON MICROSCOPY (3.28 Å) Cite: Calcium-mediated Pore Formation of Clostridioides difficile Binary Toxin To Be Published
8EKL	Clostridioides difficile binary toxin translocase CDTb wild-type after calcium depletion from receptor binding domain 1 (RBD1) - Class 1 Descriptor: ADP-ribosyltransferase binding component, CALCIUM ION Authors: Abeyawardhane, D.L, Pozharski, E. Deposit date: 2022-09-21 Release date: 2023-09-27 Method: ELECTRON MICROSCOPY (3.06 Å) Cite: Calcium-mediated Pore Formation of Clostridioides difficile Binary Toxin To Be Published
3Q8C	Crystal structure of Protective Antigen W346F (pH 5.5) Descriptor: CALCIUM ION, Protective antigen Authors: Lovell, S, Battaile, K.P, Rajapaksha, M, Janowiak, B.E, Andra, K.K, Bann, J.G. Deposit date: 2011-01-06 Release date: 2012-02-15 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.85 Å) Cite: pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2. Protein Sci., 21, 2012
3Q8A	Crystal structure of WT Protective Antigen (pH 5.5) Descriptor: CALCIUM ION, Protective antigen Authors: Rajapaksha, M, Lovell, S, Janowiak, B.E, Andra, K.K, Battaile, K.P, Bann, J.G. Deposit date: 2011-01-06 Release date: 2012-01-18 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.129 Å) Cite: pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2. Protein Sci., 21, 2012
3Q8F	Crystal structure of 2-Fluorohistine labeled Protective Antigen (pH 5.8) Descriptor: CALCIUM ION, Protective antigen, TETRAETHYLENE GLYCOL Authors: Lovell, S, Battaile, K.P, Rajapaksha, M, Janowiak, B.E, Andra, K.K, Bann, J.G. Deposit date: 2011-01-06 Release date: 2012-02-15 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2. Protein Sci., 21, 2012
3Q8B	Crystal structure of WT Protective Antigen (pH 9.0) Descriptor: CALCIUM ION, Protective antigen Authors: Lovell, S, Battaile, K.P, Rajapaksha, M, Janowiak, B.E, Andra, K.K, Bann, J.G. Deposit date: 2011-01-06 Release date: 2012-02-15 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2 Å) Cite: pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2. Protein Sci., 21, 2012
3Q8E	Crystal structure of Protective Antigen W346F (pH 8.5) Descriptor: CALCIUM ION, Protective antigen Authors: Lovell, S, Battaile, K.P, Rajapaksha, M, Janowiak, B.E, Andra, K.K, Bann, J.G. Deposit date: 2011-01-06 Release date: 2012-02-15 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.098 Å) Cite: pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2. Protein Sci., 21, 2012
6O2O	CDTb Double Heptamer Short Form Modeled from Cryo-EM Map Reconstructed using C1 Symmetry Descriptor: ADP-ribosyltransferase binding component Authors: Lacy, D.B, Sheedlo, M.J, Anderson, D.M. Deposit date: 2019-02-24 Release date: 2019-10-30 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (4.53 Å) Cite: Structural insights into the transition of Clostridioides difficile binary toxin from prepore to pore. Nat Microbiol, 5, 2020
6OKU	CDTb Double Heptamer Long Form Mask 3 Modeled from Cryo-EM Map Reconstructed using C7 Symmetry Descriptor: ADP-ribosyltransferase binding component Authors: Lacy, D.B, Sheedlo, M.J, Anderson, D.M. Deposit date: 2019-04-15 Release date: 2019-10-30 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structural insights into the transition of Clostridioides difficile binary toxin from prepore to pore. Nat Microbiol, 5, 2020
6OKS	CDTb Double Heptamer Long Form Mask 1 Modeled from Cryo-EM Map Reconstructed using C7 Symmetry Descriptor: ADP-ribosyltransferase binding component Authors: Lacy, D.B, Sheedlo, M.J, Anderson, D.M. Deposit date: 2019-04-15 Release date: 2019-10-30 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structural insights into the transition of Clostridioides difficile binary toxin from prepore to pore. Nat Microbiol, 5, 2020
6OKT	CDTb Double Heptamer Long Form Mask 1 Modeled from Cryo-EM Map Reconstructed using C7 Symmetry Descriptor: ADP-ribosyltransferase binding component Authors: Lacy, D.B, Sheedlo, M.J, Anderson, D.M. Deposit date: 2019-04-15 Release date: 2019-10-30 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structural insights into the transition of Clostridioides difficile binary toxin from prepore to pore. Nat Microbiol, 5, 2020
6OKR	CDTb Pre-Insertion form Modeled from Cryo-EM Map Reconstructed using C7 Symmetry Descriptor: ADP-ribosyltransferase binding component Authors: Lacy, D.B, Sheedlo, M.J, Anderson, D.M. Deposit date: 2019-04-15 Release date: 2019-10-30 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structural insights into the transition of Clostridioides difficile binary toxin from prepore to pore. Nat Microbiol, 5, 2020
6PSN	Anthrax toxin protective antigen channels bound to lethal factor Descriptor: CALCIUM ION, Lethal factor, Protective antigen Authors: Hardenbrook, N.J, Liu, S, Zhou, K, Zhou, Z.H, Krantz, B.A. Deposit date: 2019-07-12 Release date: 2020-03-04 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (4.6 Å) Cite: Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors. Nat Commun, 11, 2020
6UWI	Crystal structure of the Clostridium difficile translocase CDTb Descriptor: ADP-ribosyltransferase binding component, CALCIUM ION Authors: Pozharski, E. Deposit date: 2019-11-05 Release date: 2020-01-22 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (3.7 Å) Cite: Structure of the cell-binding component of theClostridium difficilebinary toxin reveals a di-heptamer macromolecular assembly. Proc.Natl.Acad.Sci.USA, 117, 2020
6UZB	Anthrax toxin protective antigen channels bound to edema factor Descriptor: CALCIUM ION, Calmodulin-sensitive adenylate cyclase, Protective antigen Authors: Hardenbrook, N.J, Liu, S, Zhou, K, Zhou, Z.H, Krantz, B.A. Deposit date: 2019-11-14 Release date: 2020-03-04 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors. Nat Commun, 11, 2020
6UWT	Clostridium difficile binary toxin translocase CDTb tetradecamer in symmetric conformation Descriptor: ADP-ribosyltransferase binding component, CALCIUM ION Authors: Xu, X, Pozharski, E, des Georges, A. Deposit date: 2019-11-05 Release date: 2020-01-22 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structure of the cell-binding component of theClostridium difficilebinary toxin reveals a di-heptamer macromolecular assembly. Proc.Natl.Acad.Sci.USA, 117, 2020
6V1S	Structure of the Clostridioides difficile transferase toxin Descriptor: ADP-ribosylating binary toxin enzymatic subunit CdtA, ADP-ribosyltransferase binding component, CALCIUM ION Authors: Sheedlo, M.J, Anderson, D.M, Thomas, A.K, Lacy, D.B. Deposit date: 2019-11-21 Release date: 2020-03-18 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structural elucidation of theClostridioides difficiletransferase toxin reveals a single-site binding mode for the enzyme. Proc.Natl.Acad.Sci.USA, 117, 2020

<123>