6UWI

Crystal structure of the Clostridium difficile translocase CDTb

This is a non-PDB format compatible entry.

Summary for 6UWI

• Entry DOI: 10.2210/pdb6uwi/pdb
• Descriptor: ADP-ribosyltransferase binding component, CALCIUM ION (2 entities in total)
• Functional Keywords: translocase, toxin
• Biological source: Clostridioides difficile
• Total number of polymer chains: 28
• Total formula weight: 2094380.96

Authors

Pozharski, E. (deposition date: 2019-11-05, release date: 2020-01-22, Last modification date: 2024-04-03)

• Primary citation: Xu, X.,Godoy-Ruiz, R.,Adipietro, K.A.,Peralta, C.,Ben-Hail, D.,Varney, K.M.,Cook, M.E.,Roth, B.M.,Wilder, P.T.,Cleveland, T.,Grishaev, A.,Neu, H.M.,Michel, S.L.J.,Yu, W.,Beckett, D.,Rustandi, R.R.,Lancaster, C.,Loughney, J.W.,Kristopeit, A.,Christanti, S.,Olson, J.W.,MacKerell, A.D.,Georges, A.D.,Pozharski, E.,Weber, D.J.; Structure of the cell-binding component of theClostridium difficilebinary toxin reveals a di-heptamer macromolecular assembly.; Proc.Natl.Acad.Sci.USA, 117:1049-1058, 2020; PubMed: 31896582; DOI: 10.1073/pnas.1919490117

Experimental method

X-RAY DIFFRACTION (3.7 Å)