1GL5
 
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1JU5
 | | Ternary complex of an Crk SH2 domain, Crk-derived phophopeptide, and Abl SH3 domain by NMR spectroscopy | | Descriptor: | Abl, Crk | | Authors: | Donaldson, L.W, Pawson, T, Kay, L.E, Forman-Kay, J.D. | | Deposit date: | 2001-08-23 | | Release date: | 2002-11-06 | | Last modified: | 2021-11-10 | | Method: | SOLUTION NMR | | Cite: | Structure of a regulatory complex involving the Abl SH3 domain, the Crk
SH2 domain, and a Crk-derived phosphopeptide
Proc.Natl.Acad.Sci.USA, 99, 2002
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1JQQ
 | | Crystal structure of Pex13p(301-386) SH3 domain | | Descriptor: | PEROXISOMAL MEMBRANE PROTEIN PAS20 | | Authors: | Douangamath, A, Mayans, O, Barnett, P, Distel, B, Wilmanns, M. | | Deposit date: | 2001-08-08 | | Release date: | 2002-12-06 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Topography for Independent Binding of alpha-Helical and PPII-Helical Ligands to a Peroxisomal SH3 Domain
Mol.Cell, 10, 2002
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1JO8
 | | Structural analysis of the yeast actin binding protein Abp1 SH3 domain | | Descriptor: | ACTIN BINDING PROTEIN, SULFATE ION | | Authors: | Fazi, B, Cope, M.J, Douangamath, A, Ferracuti, S, Schirwitz, K, Zucconi, A, Drubin, D.G, Wilmanns, M, Cesareni, G, Castagnoli, L. | | Deposit date: | 2001-07-27 | | Release date: | 2002-03-01 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Unusual binding properties of the SH3 domain of the yeast actin-binding protein Abp1: structural and functional analysis.
J.Biol.Chem., 277, 2002
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1JEG
 | | Solution structure of the SH3 domain from C-terminal Src Kinase complexed with a peptide from the tyrosine phosphatase PEP | | Descriptor: | HEMATOPOIETIC CELL PROTEIN-TYROSINE PHOSPHATASE 70Z-PEP, TYROSINE-PROTEIN KINASE CSK | | Authors: | Ghose, R, Shekhtman, A, Goger, M.J, Ji, H, Cowburn, D. | | Deposit date: | 2001-06-17 | | Release date: | 2001-10-31 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | A novel, specific interaction involving the Csk SH3 domain and its natural ligand.
Nat.Struct.Biol., 8, 2001
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1H92
 | | SH3 domain of human Lck tyrosine kinase | | Descriptor: | PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK | | Authors: | Schweimer, K, Hoffmann, S, Friedrich, U, Biesinger, B, Roesch, P, Sticht, H. | | Deposit date: | 2001-02-22 | | Release date: | 2001-10-22 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural Investigation of the Binding of a Herpesviral Protein to the SH3 Domain of Tyrosine Kinase Lck
Biochemistry, 41, 2002
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1H8K
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1I07
 | | EPS8 SH3 DOMAIN INTERTWINED DIMER | | Descriptor: | EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8 | | Authors: | Kishan, K.V.R, Newcomer, M.E. | | Deposit date: | 2001-01-29 | | Release date: | 2001-05-09 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Effect of pH and salt bridges on structural assembly: molecular structures of the monomer and intertwined dimer of the Eps8 SH3 domain.
Protein Sci., 10, 2001
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1I0C
 | | EPS8 SH3 CLOSED MONOMER | | Descriptor: | EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8 | | Authors: | Kishan, K.V.R, Newcomer, M.E. | | Deposit date: | 2001-01-29 | | Release date: | 2001-05-09 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Effect of pH and salt bridges on structural assembly: molecular structures of the monomer and intertwined dimer of the Eps8 SH3 domain.
Protein Sci., 10, 2001
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1IO6
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1G83
 | | CRYSTAL STRUCTURE OF FYN SH3-SH2 | | Descriptor: | PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN | | Authors: | Arold, S.T, Ulmer, T.S, Mulhern, T.D, Werner, J.M, Ladbury, J.E, Campbell, I.D, Noble, M.E.M. | | Deposit date: | 2000-11-16 | | Release date: | 2001-05-30 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases.
J.Biol.Chem., 276, 2001
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1HD3
 | | A-SPECTRIN SH3 DOMAIN F52Y MUTANT | | Descriptor: | GLYCEROL, SPECTRIN ALPHA CHAIN, SULFATE ION | | Authors: | Vega, M.C, Viguera, A.R, Serrano, L. | | Deposit date: | 2000-11-06 | | Release date: | 2001-11-01 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Unspecific Hydrophobic Stabilization of Folding Transition States
Proc.Natl.Acad.Sci.USA, 99, 2002
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1G2B
 | | ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, CIRCULAR PERMUTANT, CUT AT N47-D48 | | Descriptor: | SPECTRIN ALPHA CHAIN, SULFATE ION | | Authors: | Berisio, R, Viguera, A.R, Serrano, L, Wilmanns, M. | | Deposit date: | 2000-10-18 | | Release date: | 2000-11-01 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.12 Å) | | Cite: | Atomic resolution structure of a mutant of the spectrin SH3 domain.
Acta Crystallogr.,Sect.D, 57, 2001
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1E7O
 | | A-SPECTRIN SH3 DOMAIN A11V, V23L, M25V, V44I, V58L MUTATIONS | | Descriptor: | GLYCEROL, SPECTRIN ALPHA CHAIN | | Authors: | Vega, M.C, Serrano, L. | | Deposit date: | 2000-08-31 | | Release date: | 2003-05-21 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | A Thermodynamic and Kinetic Analysis of the Folding Pathway of an SH3 Domain Entropically Stabilised by a Redesigned Hydrophobic Core
J.Mol.Biol., 328, 2003
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1E6H
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1E6G
 | | A-SPECTRIN SH3 DOMAIN A11V, V23L, M25I, V53I, V58L MUTANT | | Descriptor: | SPECTRIN ALPHA CHAIN, SULFATE ION | | Authors: | Vega, M.C, Serrano, L. | | Deposit date: | 2000-08-15 | | Release date: | 2002-05-23 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Conformational Strain in the Hydrophobic Core and its Implications for Protein Folding and Design
Nat.Struct.Biol., 9, 2002
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1GCQ
 | | CRYSTAL STRUCTURE OF VAV AND GRB2 SH3 DOMAINS | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, VAV PROTO-ONCOGENE | | Authors: | Nishida, M, Nagata, K, Hachimori, Y, Ogura, K, Inagaki, F. | | Deposit date: | 2000-08-08 | | Release date: | 2001-08-08 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | Novel recognition mode between Vav and Grb2 SH3 domains.
EMBO J., 20, 2001
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1GCP
 | | CRYSTAL STRUCTURE OF VAV SH3 DOMAIN | | Descriptor: | VAV PROTO-ONCOGENE | | Authors: | Nishida, M, Nagata, K, Hachimori, Y, Ogura, K, Inagaki, F. | | Deposit date: | 2000-08-08 | | Release date: | 2001-08-08 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Novel recognition mode between Vav and Grb2 SH3 domains.
EMBO J., 20, 2001
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1QLY
 | | NMR Study of the SH3 Domain From Bruton's Tyrosine Kinase, 20 Structures | | Descriptor: | TYROSINE-PROTEIN KINASE BTK | | Authors: | Tzeng, S.R, Lou, Y.C, Pai, M.T, Chen, C, Chen, S.H, Cheng, J.Y. | | Deposit date: | 1999-09-20 | | Release date: | 1999-12-14 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of the Human Btk SH3 Domain Complexed with a Proline-Rich Peptide from P120Cbl
J.Biomol.NMR, 16, 2000
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1QKX
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1QKW
 | | Alpha-spectrin Src Homology 3 domain, N47G mutant in the distal loop. | | Descriptor: | ALPHA II SPECTRIN, GLYCEROL, SULFATE ION | | Authors: | Vega, M.C, Martinez, J, Serrano, L. | | Deposit date: | 1999-08-16 | | Release date: | 2000-08-18 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Thermodynamic and structural characterization of Asn and Ala residues in the disallowed II' region of the Ramachandran plot.
Protein Sci., 9, 2000
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1QCF
 | | CRYSTAL STRUCTURE OF HCK IN COMPLEX WITH A SRC FAMILY-SELECTIVE TYROSINE KINASE INHIBITOR | | Descriptor: | 1-TER-BUTYL-3-P-TOLYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE, Tyrosine-protein kinase HCK | | Authors: | Schindler, T, Sicheri, F, Pico, A, Gazit, A, Levitzki, A, Kuriyan, J. | | Deposit date: | 1999-05-04 | | Release date: | 1999-06-08 | | Last modified: | 2022-12-21 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of Hck in complex with a Src family-selective tyrosine kinase inhibitor.
Mol.Cell, 3, 1999
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2SRC
 | | CRYSTAL STRUCTURE OF HUMAN TYROSINE-PROTEIN KINASE C-SRC, IN COMPLEX WITH AMP-PNP | | Descriptor: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, TYROSINE-PROTEIN KINASE SRC | | Authors: | Xu, W, Doshi, A, Lei, M, Eck, M.J, Harrison, S.C. | | Deposit date: | 1998-12-29 | | Release date: | 1999-07-22 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal structures of c-Src reveal features of its autoinhibitory mechanism.
Mol.Cell, 3, 1999
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1B07
 | | CRK SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR | | Descriptor: | PHENYLETHANE, PROTEIN (PROTO-ONCOGENE CRK (CRK)), PROTEIN (SH3 PEPTOID INHIBITOR) | | Authors: | Nguyen, J.T, Turck, C.W, Cohen, F.E, Zuckermann, R.N, Lim, W.A. | | Deposit date: | 1998-11-17 | | Release date: | 1999-01-06 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors.
Science, 282, 1998
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2SEM
 | | SEM5 SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR | | Descriptor: | PROTEIN (SEX MUSCLE ABNORMAL PROTEIN 5), PROTEIN (SH3 PEPTOID INHIBITOR) | | Authors: | Nguyen, J.T, Turck, C.W, Cohen, F.E, Zuckermann, R.N, Lim, W.A. | | Deposit date: | 1998-11-02 | | Release date: | 1999-01-06 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors.
Science, 282, 1998
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