1B07
CRK SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR
Summary for 1B07
Entry DOI | 10.2210/pdb1b07/pdb |
Descriptor | PROTEIN (PROTO-ONCOGENE CRK (CRK)), PROTEIN (SH3 PEPTOID INHIBITOR), PHENYLETHANE, ... (4 entities in total) |
Functional Keywords | sh3 domain, inhibitors, peptoids, protein-protein recognition, proline-rich motifs, signal transduction |
Biological source | Mus musculus (house mouse) |
Cellular location | Cytoplasm (By similarity): Q64010 |
Total number of polymer chains | 2 |
Total formula weight | 9319.37 |
Authors | Nguyen, J.T.,Turck, C.W.,Cohen, F.E.,Zuckermann, R.N.,Lim, W.A. (deposition date: 1998-11-17, release date: 1999-01-06, Last modification date: 2023-08-09) |
Primary citation | Nguyen, J.T.,Turck, C.W.,Cohen, F.E.,Zuckermann, R.N.,Lim, W.A. Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors. Science, 282:2088-2092, 1998 Cited by PubMed: 9851931DOI: 10.1126/science.282.5396.2088 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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