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8VFV
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BU of 8vfv by Molmil
HIV Env BG505_MD39_B16 SOSIP boosting trimer in complex with B16_d77.5 mouse Fab and RM20A3 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, B16_d77.5 mouse Fab heavy chain Fv, ...
Authors:Ozorowski, G, Torres, J.L, Ward, A.B.
Deposit date:2023-12-22
Release date:2024-05-15
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:mRNA-LNP HIV-1 trimer boosters elicit precursors to broad neutralizing antibodies.
Science, 384, 2024
8RK2
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BU of 8rk2 by Molmil
Human Replication protein A (RPA; trimeric core) - ssDNA complex
Descriptor: Replication protein A 14 kDa subunit, Replication protein A 32 kDa subunit, Replication protein A 70 kDa DNA-binding subunit, ...
Authors:Liang, C.C, West, S.C.
Deposit date:2023-12-22
Release date:2024-04-24
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Mechanism of single-stranded DNA annealing by RAD52-RPA complex.
Nature, 629, 2024
8VFH
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BU of 8vfh by Molmil
Ternary DNA Polymerase Beta bound to DNA containing primer terminal FapydG base-paired with a dC
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*CP*GP*AP*CP*GP*CP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(FAP))-3'), ...
Authors:Oden, P.N, Ryan, B.J, Freudenthal, B.D.
Deposit date:2023-12-21
Release date:2024-05-08
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta.
Nucleic Acids Res., 52, 2024
8VFA
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BU of 8vfa by Molmil
Ternary DNA Polymerase Beta bound to DNA containing primer terminal dC base-paired with FapydG
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*CP*(FAP)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Oden, P.N, Ryan, B.J, Freudenthal, B.D.
Deposit date:2023-12-21
Release date:2024-05-08
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta.
Nucleic Acids Res., 52, 2024
8VFB
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BU of 8vfb by Molmil
Ternary DNA Polymerase Beta bound to DNA containing primer terminal dA base-paired with FapydG
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*CP*(FAP)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Oden, P.N, Ryan, B.J, Freudenthal, B.D.
Deposit date:2023-12-21
Release date:2024-05-08
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta.
Nucleic Acids Res., 52, 2024
8VFD
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BU of 8vfd by Molmil
Ternary DNA Polymerase Beta bound to DNA containing template FapydG incoming TTP analog
Descriptor: 1-{2-deoxy-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]-beta-D-threo-pentofuranosyl}-5-methylpyrimidine-2,4(1H,3H)-dione, DNA (5'-D(*CP*CP*GP*AP*CP*(FAP)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
Authors:Oden, P.N, Ryan, B.J, Freudenthal, B.D.
Deposit date:2023-12-21
Release date:2024-05-08
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta.
Nucleic Acids Res., 52, 2024
8VFI
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BU of 8vfi by Molmil
Ternary DNA Polymerase Beta bound to DNA containing primer terminal FapydG base-paired with a dA
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*GP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ...
Authors:Oden, P.N, Ryan, B.J, Freudenthal, B.D.
Deposit date:2023-12-21
Release date:2024-05-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta.
Nucleic Acids Res., 52, 2024
8RJW
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BU of 8rjw by Molmil
Human RAD52 open ring - ssDNA complex
Descriptor: DNA repair protein RAD52 homolog, MAGNESIUM ION, ssDNA
Authors:Liang, C.C, West, S.C.
Deposit date:2023-12-21
Release date:2024-04-24
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Mechanism of single-stranded DNA annealing by RAD52-RPA complex.
Nature, 629, 2024
8XJG
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BU of 8xjg by Molmil
Crystal structure of the YqeY protein from Vibrio parahaemolyticus
Descriptor: YqeY, ZINC ION
Authors:Kim, S.Y, Yoon, S.I.
Deposit date:2023-12-21
Release date:2024-05-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural analysis of the YqeY proteins from Campylobacter jejuni and Vibrio parahaemolyticus.
Biochem.Biophys.Res.Commun., 695, 2024
8XJE
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BU of 8xje by Molmil
Crystal structure of the YqeY protein from Campylobacter jejuni
Descriptor: YqeY
Authors:Kim, S.Y, Yoon, S.I.
Deposit date:2023-12-21
Release date:2024-05-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural analysis of the YqeY proteins from Campylobacter jejuni and Vibrio parahaemolyticus.
Biochem.Biophys.Res.Commun., 695, 2024
8VEV
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BU of 8vev by Molmil
Structure of a mouse IgG antibody antigen-binding fragment (Fab) targeting N6-methyladenosine (m6A), an RNA modification, m6A nucleoside ligand
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, N-methyladenosine, ...
Authors:Aoki, S.T.
Deposit date:2023-12-20
Release date:2024-02-07
Method:X-RAY DIFFRACTION (3.06 Å)
Cite:Structure of a mouse IgG antibody antigen-binding fragment (Fab) targeting N6-methyladenosine (m6A), an RNA modification, m6A nucleoside ligand
To Be Published
8RJC
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BU of 8rjc by Molmil
Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in complex with Sec61-TRAP, open conformation 1
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Lewis, A.J.O, Hegde, R.S.
Deposit date:2023-12-20
Release date:2024-01-24
Method:ELECTRON MICROSCOPY (2.90061 Å)
Cite:Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in complex with Sec61-TRAP, open conformation 1
To Be Published
8RJD
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BU of 8rjd by Molmil
Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in complex with Sec61-TRAP, open conformation 2
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Lewis, A.J.O, Hegde, R.S.
Deposit date:2023-12-20
Release date:2024-01-24
Method:ELECTRON MICROSCOPY (2.78574 Å)
Cite:Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in complex with Sec61-TRAP, open conformation 2
To Be Published
8RJB
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BU of 8rjb by Molmil
Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in complex with Sec61-RAMP4
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Lewis, A.J.O, Hegde, R.S.
Deposit date:2023-12-20
Release date:2024-01-24
Method:ELECTRON MICROSCOPY (2.69243 Å)
Cite:Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in complex with Sec61-RAMP4
To Be Published
8XI6
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BU of 8xi6 by Molmil
SARS-CoV-2 Omicron BQ.1.1 Variant Spike Protein Complexed with MO11 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Ishimaru, H, Nishimura, M, Shigematsu, H, Marini, M.I, Hasegawa, N, Takamiya, R, Iwata, S, Mori, Y.
Deposit date:2023-12-19
Release date:2024-04-24
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Epitopes of an antibody that neutralizes a wide range of SARS-CoV-2 variants in a conserved subdomain 1 of the spike protein.
J.Virol., 98, 2024
8RIV
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BU of 8riv by Molmil
T2R-TTL-1-K08 complex
Descriptor: (4-fluoranyl-2-methyl-1~{H}-indol-5-yl) 3,4,5-trimethoxybenzenesulfonate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Boiarska, Z, Homer, J.A, Steinmetz, M.O, Moses, J.E, Prota, A.E.P.
Deposit date:2023-12-19
Release date:2024-03-27
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Modular synthesis of functional libraries by accelerated SuFEx click chemistry.
Chem Sci, 15, 2024
8RIW
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BU of 8riw by Molmil
T2R-TTL-1-L01 complex
Descriptor: (2-methyl-1~{H}-indol-5-yl) 3,4,5-trimethoxybenzenesulfonate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Prota, A.E.P, Boiarska, Z, Homer, J.A, Steinmetz, M.O, Moses, J.E.
Deposit date:2023-12-19
Release date:2024-03-27
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Modular synthesis of functional libraries by accelerated SuFEx click chemistry.
Chem Sci, 15, 2024
8RJ3
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BU of 8rj3 by Molmil
Human RAD52 open ring conformation
Descriptor: DNA repair protein RAD52 homolog
Authors:Liang, C.C, West, S.C.
Deposit date:2023-12-19
Release date:2024-04-24
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Mechanism of single-stranded DNA annealing by RAD52-RPA complex.
Nature, 629, 2024
8RI0
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BU of 8ri0 by Molmil
Crystal structure of Tm1570 domain from Calditerrivibrio nitroreducens in complex with S-adenosyl-L-methionine
Descriptor: S-ADENOSYLMETHIONINE, tRNA (guanine-N(1)-)-methyltransferase
Authors:Kluza, A, Lewandowska, I, Sulkowska, J.
Deposit date:2023-12-18
Release date:2024-01-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Are there double knots in proteins? Prediction and in vitro verification based on TrmD-Tm1570 fusion from C. nitroreducens. To be published
To Be Published
8RI9
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BU of 8ri9 by Molmil
Late alpha-Synuclein fibril structure from liquid-liquid phase separations.
Descriptor: Alpha-synuclein
Authors:De Simone, A, Barritt, J.D, Chen, S, Cascella, R, Cecchi, C, Bigi, A, Jarvis, J.A, Chiti, F, Dobson, C.M, Fusco, G.
Deposit date:2023-12-18
Release date:2024-03-06
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure-Toxicity Relationship in Intermediate Fibrils from alpha-Synuclein Condensates.
J.Am.Chem.Soc., 146, 2024
8RIL
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BU of 8ril by Molmil
Human RAD52 closed ring conformation
Descriptor: DNA repair protein RAD52 homolog
Authors:Liang, C.C, West, S.C.
Deposit date:2023-12-18
Release date:2024-04-24
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Mechanism of single-stranded DNA annealing by RAD52-RPA complex.
Nature, 629, 2024
8XHR
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BU of 8xhr by Molmil
Crystal structure of Mycobacterium tuberculosis MenT3 bound with CTP
Descriptor: CYTIDINE-5'-TRIPHOSPHATE, Nucleotidyl transferase AbiEii/AbiGii toxin family protein
Authors:Liu, J, Yashiro, Y, Tomita, K.
Deposit date:2023-12-18
Release date:2024-02-28
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Substrate specificity of Mycobacterium tuberculosis tRNA terminal nucleotidyltransferase toxin MenT3.
Nucleic Acids Res., 52, 2024
8VDS
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BU of 8vds by Molmil
DNA Ligase 1 with nick DNA 3'rG:C
Descriptor: DNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*CP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA ligase 1, DNA/RNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*T)-R(P*G)-D(P*GP*TP*CP*GP*GP*AP*C)-3')
Authors:KanalElamparithi, B, Gulkis, M, Caglayan, M.
Deposit date:2023-12-17
Release date:2024-05-22
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structures of LIG1 provide a mechanistic basis for understanding a lack of sugar discrimination against a ribonucleotide at the 3'-end of nick DNA.
J.Biol.Chem., 300, 2024
8VDT
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BU of 8vdt by Molmil
DNA Ligase 1 with nick DNA 3'rA:T
Descriptor: DNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*TP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA ligase 1, DNA/RNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*T)-R(P*A)-D(P*GP*TP*CP*GP*GP*AP*C)-3'), ...
Authors:KanalElamparithi, B, Gulkis, M, Caglayan, M.
Deposit date:2023-12-17
Release date:2024-05-22
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Structures of LIG1 provide a mechanistic basis for understanding a lack of sugar discrimination against a ribonucleotide at the 3'-end of nick DNA.
J.Biol.Chem., 300, 2024
8XGY
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BU of 8xgy by Molmil
Crystal structure of human Golgi resident glutaminyl cyclase in complex with (R,Z)-3-((1H-benzo[d]imidazol-5-yl)methylene)-4-((1-acetylpyrrolidin-3-yl)oxy)indolin-2-one
Descriptor: (3~{Z})-3-(1~{H}-benzimidazol-5-ylmethylidene)-4-[(3~{R})-1-ethanoylpyrrolidin-3-yl]oxy-1~{H}-indol-2-one, Glutaminyl-peptide cyclotransferase, ZINC ION
Authors:Li, G.-B, Wang, X.-Y.
Deposit date:2023-12-16
Release date:2024-06-12
Last modified:2024-06-26
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:X-ray Structure-Guided Discovery of a Potent Benzimidazole Glutaminyl Cyclase Inhibitor That Shows Activity in a Parkinson's Disease Mouse Model.
J.Med.Chem., 67, 2024

221716

數據於2024-06-26公開中

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