8VFV
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![BU of 8vfv by Molmil](/molmil-images/mine/8vfv) | HIV Env BG505_MD39_B16 SOSIP boosting trimer in complex with B16_d77.5 mouse Fab and RM20A3 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, B16_d77.5 mouse Fab heavy chain Fv, ... | Authors: | Ozorowski, G, Torres, J.L, Ward, A.B. | Deposit date: | 2023-12-22 | Release date: | 2024-05-15 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | mRNA-LNP HIV-1 trimer boosters elicit precursors to broad neutralizing antibodies. Science, 384, 2024
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8RK2
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![BU of 8rk2 by Molmil](/molmil-images/mine/8rk2) | Human Replication protein A (RPA; trimeric core) - ssDNA complex | Descriptor: | Replication protein A 14 kDa subunit, Replication protein A 32 kDa subunit, Replication protein A 70 kDa DNA-binding subunit, ... | Authors: | Liang, C.C, West, S.C. | Deposit date: | 2023-12-22 | Release date: | 2024-04-24 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Mechanism of single-stranded DNA annealing by RAD52-RPA complex. Nature, 629, 2024
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8VFH
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![BU of 8vfh by Molmil](/molmil-images/mine/8vfh) | Ternary DNA Polymerase Beta bound to DNA containing primer terminal FapydG base-paired with a dC | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*CP*GP*AP*CP*GP*CP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(FAP))-3'), ... | Authors: | Oden, P.N, Ryan, B.J, Freudenthal, B.D. | Deposit date: | 2023-12-21 | Release date: | 2024-05-08 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta. Nucleic Acids Res., 52, 2024
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8VFA
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![BU of 8vfa by Molmil](/molmil-images/mine/8vfa) | Ternary DNA Polymerase Beta bound to DNA containing primer terminal dC base-paired with FapydG | Descriptor: | DNA (5'-D(*CP*CP*GP*AP*CP*CP*(FAP)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... | Authors: | Oden, P.N, Ryan, B.J, Freudenthal, B.D. | Deposit date: | 2023-12-21 | Release date: | 2024-05-08 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta. Nucleic Acids Res., 52, 2024
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8VFB
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![BU of 8vfb by Molmil](/molmil-images/mine/8vfb) | Ternary DNA Polymerase Beta bound to DNA containing primer terminal dA base-paired with FapydG | Descriptor: | DNA (5'-D(*CP*CP*GP*AP*CP*CP*(FAP)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... | Authors: | Oden, P.N, Ryan, B.J, Freudenthal, B.D. | Deposit date: | 2023-12-21 | Release date: | 2024-05-08 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta. Nucleic Acids Res., 52, 2024
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8VFD
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![BU of 8vfd by Molmil](/molmil-images/mine/8vfd) | Ternary DNA Polymerase Beta bound to DNA containing template FapydG incoming TTP analog | Descriptor: | 1-{2-deoxy-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]-beta-D-threo-pentofuranosyl}-5-methylpyrimidine-2,4(1H,3H)-dione, DNA (5'-D(*CP*CP*GP*AP*CP*(FAP)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... | Authors: | Oden, P.N, Ryan, B.J, Freudenthal, B.D. | Deposit date: | 2023-12-21 | Release date: | 2024-05-08 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta. Nucleic Acids Res., 52, 2024
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8VFI
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![BU of 8vfi by Molmil](/molmil-images/mine/8vfi) | Ternary DNA Polymerase Beta bound to DNA containing primer terminal FapydG base-paired with a dA | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*GP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... | Authors: | Oden, P.N, Ryan, B.J, Freudenthal, B.D. | Deposit date: | 2023-12-21 | Release date: | 2024-05-15 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta. Nucleic Acids Res., 52, 2024
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8RJW
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![BU of 8rjw by Molmil](/molmil-images/mine/8rjw) | Human RAD52 open ring - ssDNA complex | Descriptor: | DNA repair protein RAD52 homolog, MAGNESIUM ION, ssDNA | Authors: | Liang, C.C, West, S.C. | Deposit date: | 2023-12-21 | Release date: | 2024-04-24 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Mechanism of single-stranded DNA annealing by RAD52-RPA complex. Nature, 629, 2024
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8XJG
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![BU of 8xjg by Molmil](/molmil-images/mine/8xjg) | |
8XJE
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![BU of 8xje by Molmil](/molmil-images/mine/8xje) | |
8VEV
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![BU of 8vev by Molmil](/molmil-images/mine/8vev) | |
8RJC
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![BU of 8rjc by Molmil](/molmil-images/mine/8rjc) | |
8RJD
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![BU of 8rjd by Molmil](/molmil-images/mine/8rjd) | |
8RJB
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![BU of 8rjb by Molmil](/molmil-images/mine/8rjb) | |
8XI6
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![BU of 8xi6 by Molmil](/molmil-images/mine/8xi6) | SARS-CoV-2 Omicron BQ.1.1 Variant Spike Protein Complexed with MO11 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Ishimaru, H, Nishimura, M, Shigematsu, H, Marini, M.I, Hasegawa, N, Takamiya, R, Iwata, S, Mori, Y. | Deposit date: | 2023-12-19 | Release date: | 2024-04-24 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Epitopes of an antibody that neutralizes a wide range of SARS-CoV-2 variants in a conserved subdomain 1 of the spike protein. J.Virol., 98, 2024
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8RIV
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![BU of 8riv by Molmil](/molmil-images/mine/8riv) | T2R-TTL-1-K08 complex | Descriptor: | (4-fluoranyl-2-methyl-1~{H}-indol-5-yl) 3,4,5-trimethoxybenzenesulfonate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | Authors: | Boiarska, Z, Homer, J.A, Steinmetz, M.O, Moses, J.E, Prota, A.E.P. | Deposit date: | 2023-12-19 | Release date: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | Modular synthesis of functional libraries by accelerated SuFEx click chemistry. Chem Sci, 15, 2024
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8RIW
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![BU of 8riw by Molmil](/molmil-images/mine/8riw) | T2R-TTL-1-L01 complex | Descriptor: | (2-methyl-1~{H}-indol-5-yl) 3,4,5-trimethoxybenzenesulfonate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | Authors: | Prota, A.E.P, Boiarska, Z, Homer, J.A, Steinmetz, M.O, Moses, J.E. | Deposit date: | 2023-12-19 | Release date: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Modular synthesis of functional libraries by accelerated SuFEx click chemistry. Chem Sci, 15, 2024
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8RJ3
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![BU of 8rj3 by Molmil](/molmil-images/mine/8rj3) | Human RAD52 open ring conformation | Descriptor: | DNA repair protein RAD52 homolog | Authors: | Liang, C.C, West, S.C. | Deposit date: | 2023-12-19 | Release date: | 2024-04-24 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Mechanism of single-stranded DNA annealing by RAD52-RPA complex. Nature, 629, 2024
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8RI0
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![BU of 8ri0 by Molmil](/molmil-images/mine/8ri0) | |
8RI9
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![BU of 8ri9 by Molmil](/molmil-images/mine/8ri9) | Late alpha-Synuclein fibril structure from liquid-liquid phase separations. | Descriptor: | Alpha-synuclein | Authors: | De Simone, A, Barritt, J.D, Chen, S, Cascella, R, Cecchi, C, Bigi, A, Jarvis, J.A, Chiti, F, Dobson, C.M, Fusco, G. | Deposit date: | 2023-12-18 | Release date: | 2024-03-06 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure-Toxicity Relationship in Intermediate Fibrils from alpha-Synuclein Condensates. J.Am.Chem.Soc., 146, 2024
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8RIL
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![BU of 8ril by Molmil](/molmil-images/mine/8ril) | Human RAD52 closed ring conformation | Descriptor: | DNA repair protein RAD52 homolog | Authors: | Liang, C.C, West, S.C. | Deposit date: | 2023-12-18 | Release date: | 2024-04-24 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Mechanism of single-stranded DNA annealing by RAD52-RPA complex. Nature, 629, 2024
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8XHR
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![BU of 8xhr by Molmil](/molmil-images/mine/8xhr) | |
8VDS
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![BU of 8vds by Molmil](/molmil-images/mine/8vds) | DNA Ligase 1 with nick DNA 3'rG:C | Descriptor: | DNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*CP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA ligase 1, DNA/RNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*T)-R(P*G)-D(P*GP*TP*CP*GP*GP*AP*C)-3') | Authors: | KanalElamparithi, B, Gulkis, M, Caglayan, M. | Deposit date: | 2023-12-17 | Release date: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Structures of LIG1 provide a mechanistic basis for understanding a lack of sugar discrimination against a ribonucleotide at the 3'-end of nick DNA. J.Biol.Chem., 300, 2024
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8VDT
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![BU of 8vdt by Molmil](/molmil-images/mine/8vdt) | DNA Ligase 1 with nick DNA 3'rA:T | Descriptor: | DNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*TP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA ligase 1, DNA/RNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*T)-R(P*A)-D(P*GP*TP*CP*GP*GP*AP*C)-3'), ... | Authors: | KanalElamparithi, B, Gulkis, M, Caglayan, M. | Deposit date: | 2023-12-17 | Release date: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | Structures of LIG1 provide a mechanistic basis for understanding a lack of sugar discrimination against a ribonucleotide at the 3'-end of nick DNA. J.Biol.Chem., 300, 2024
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8XGY
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![BU of 8xgy by Molmil](/molmil-images/mine/8xgy) | |