8VFA

Ternary DNA Polymerase Beta bound to DNA containing primer terminal dC base-paired with FapydG

Summary for 8VFA

• Entry DOI: 10.2210/pdb8vfa/pdb
• Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*CP*(FAP)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... (8 entities in total)
• Functional Keywords: fapydg, polymerase beta, primer terminus, pol beta, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 48362.92

Authors

Oden, P.N.,Ryan, B.J.,Freudenthal, B.D. (deposition date: 2023-12-21, release date: 2024-05-08)

• Primary citation: Gao, S.,Oden, P.N.,Ryan, B.J.,Yang, H.,Freudenthal, B.D.,Greenberg, M.M.; Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta.; Nucleic Acids Res., 2024; PubMed: 38634780; DOI: 10.1093/nar/gkae277

Experimental method

X-RAY DIFFRACTION (2.05 Å)