3EI4
| Structure of the hsDDB1-hsDDB2 complex | Descriptor: | DNA damage-binding protein 1, DNA damage-binding protein 2 | Authors: | Scrima, A, Pavletich, N.P, Thoma, N.H. | Deposit date: | 2008-09-15 | Release date: | 2009-01-20 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex. Cell(Cambridge,Mass.), 135, 2008
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7BO7
| CRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX with JNJB44355437 | Descriptor: | (2~{R},3~{R},4~{S},5~{R})-2-[(4~{a}~{S},7~{a}~{S})-4-azanyl-1,4,4~{a},7~{a}-tetrahydropyrrolo[2,3-d]pyrimidin-7-yl]-5-(quinolin-7-yloxymethyl)oxolane-3,4-diol, 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Brown, D, Robinson, C, Carr, K.H, Pande, V. | Deposit date: | 2021-01-24 | Release date: | 2022-03-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.83 Å) | Cite: | CRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX with JNJB44355437 To Be Published
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4XMN
| Structure of the yeast coat nucleoporin complex, space group P212121 | Descriptor: | Antibody 87 heavy chain, Antibody 87 light chain, Nucleoporin NUP120, ... | Authors: | Stuwe, T, Correia, A.R, Lin, D.H, Paduch, M, Lu, V.T, Kossiakoff, A.A, Hoelz, A. | Deposit date: | 2015-01-14 | Release date: | 2015-03-25 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (7.6 Å) | Cite: | Nuclear pores. Architecture of the nuclear pore complex coat. Science, 347, 2015
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4XMM
| Structure of the yeast coat nucleoporin complex, space group C2 | Descriptor: | Antibody 57 heavy chain, Antibody 57 light chain, Nucleoporin NUP120, ... | Authors: | Stuwe, T, Correia, A.R, Lin, D.H, Paduch, M, Lu, V.T, Kossiakoff, A.A, Hoelz, A. | Deposit date: | 2015-01-14 | Release date: | 2015-03-25 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (7.384 Å) | Cite: | Nuclear pores. Architecture of the nuclear pore complex coat. Science, 347, 2015
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4XYH
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4XYI
| Mis16 with H4 peptide | Descriptor: | Histone H4, Kinetochore protein Mis16 | Authors: | An, S, Kim, H, Cho, U.-S. | Deposit date: | 2015-02-02 | Release date: | 2016-02-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Mis16 Independently Recognizes Histone H4 and the CENP-ACnp1-Specific Chaperone Scm3sp. J.Mol.Biol., 427, 2015
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4YCZ
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4X60
| Crystal structure of PRMT5:MEP50 with EPZ015666 and sinefungin | Descriptor: | GLYCEROL, Methylosome protein 50, N-[(2S)-3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl]-6-(oxetan-3-ylamino)pyrimidine-4-carboxamide, ... | Authors: | Boriack-Sjodin, P.A. | Deposit date: | 2014-12-06 | Release date: | 2015-04-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models. Nat.Chem.Biol., 11, 2015
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4WJV
| Crystal structure of Rsa4 in complex with the Nsa2 binding peptide | Descriptor: | Maltose-binding periplasmic protein, Ribosome assembly protein 4, Ribosome biogenesis protein NSA2, ... | Authors: | Holdermann, I, Paternoga, H, Bassler, J, Hurt, E, Sinning, I. | Deposit date: | 2014-10-01 | Release date: | 2014-11-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation. J.Cell Biol., 207, 2014
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4WJU
| Crystal structure of Rsa4 from Saccharomyces cerevisiae | Descriptor: | GLYCEROL, Ribosome assembly protein 4 | Authors: | Holdermann, I, Bassler, J, Hurt, E, Sinning, I. | Deposit date: | 2014-10-01 | Release date: | 2014-11-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation. J.Cell Biol., 207, 2014
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4X63
| Crystal structure of PRMT5:MEP50 with EPZ015666 and SAH | Descriptor: | Methylosome protein 50, N-[(2S)-3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl]-6-(oxetan-3-ylamino)pyrimidine-4-carboxamide, Protein arginine N-methyltransferase 5, ... | Authors: | Boriack-Sjodin, P.A. | Deposit date: | 2014-12-06 | Release date: | 2015-04-22 | Last modified: | 2015-05-27 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models. Nat.Chem.Biol., 11, 2015
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4X61
| Crystal structure of PRMT5:MEP50 with EPZ015666 and SAM | Descriptor: | GLYCEROL, Methylosome protein 50, N-[(2S)-3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl]-6-(oxetan-3-ylamino)pyrimidine-4-carboxamide, ... | Authors: | Boriack-Sjodin, P.A. | Deposit date: | 2014-12-06 | Release date: | 2015-04-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models. Nat.Chem.Biol., 11, 2015
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4U7A
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4UI9
| Atomic structure of the human Anaphase-Promoting Complex | Descriptor: | ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ... | Authors: | Chang, L, Zhang, Z, Yang, J, McLaughlin, S.H, Barford, D. | Deposit date: | 2015-03-27 | Release date: | 2015-06-17 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Atomic Structure of the Apc and its Mechanism of Protein Ubiquitination Nature, 522, 2015
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5BJS
| Apo ctPRC2 in an autoinhibited state | Descriptor: | Histone-lysine N-methyltransferase EZH2, Polycomb protein SUZ12, Polycomb Protein EED, ... | Authors: | Bratkowski, M.A, Liu, X. | Deposit date: | 2016-10-22 | Release date: | 2017-06-14 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.189 Å) | Cite: | Polycomb repressive complex 2 in an autoinhibited state. J. Biol. Chem., 292, 2017
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5CVL
| WDR48 (UAF-1), residues 2-580 | Descriptor: | GOLD ION, PHOSPHATE ION, WD repeat-containing protein 48 | Authors: | HARRIS, S.F, YIN, J. | Deposit date: | 2015-07-27 | Release date: | 2015-10-07 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46. Structure, 23, 2015
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5CXC
| Structure of Ytm1 bound to the C-terminal domain of Erb1 in P 65 2 2 space group | Descriptor: | CHLORIDE ION, Ribosome biogenesis protein ERB1, Ribosome biogenesis protein YTM1 | Authors: | Wegrecki, M, Bravo, J. | Deposit date: | 2015-07-28 | Release date: | 2015-10-28 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | The structure of Erb1-Ytm1 complex reveals the functional importance of a high-affinity binding between two beta-propellers during the assembly of large ribosomal subunits in eukaryotes. Nucleic Acids Res., 43, 2015
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5CYK
| Structure of Ytm1 bound to the C-terminal domain of Erb1-R486E | Descriptor: | CHLORIDE ION, Ribosome biogenesis protein ERB1, Ribosome biogenesis protein YTM1 | Authors: | Wegrecki, M, Bravo, J. | Deposit date: | 2015-07-30 | Release date: | 2015-10-28 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The structure of Erb1-Ytm1 complex reveals the functional importance of a high-affinity binding between two beta-propellers during the assembly of large ribosomal subunits in eukaryotes. Nucleic Acids Res., 43, 2015
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5CXB
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5C9Z
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4E5Z
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4E54
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4CI8
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4BZJ
| The structure of the COPII coat assembled on membranes | Descriptor: | Protein transport protein SEC13, Protein transport protein SEC31 | Authors: | Zanetti, G, Prinz, S, Daum, S, Meister, A, Schekman, R, Bacia, K, Briggs, J.A.G. | Deposit date: | 2013-07-26 | Release date: | 2013-09-18 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (40 Å) | Cite: | The Structure of the Copii Transport-Vesicle Coat Assembled on Membranes Elife, 2, 2013
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4BZK
| The structure of the COPII coat assembled on membranes | Descriptor: | Protein transport protein SEC13, Protein transport protein SEC31 | Authors: | Zanetti, G, Prinz, S, Daum, S, Meister, A, Schekman, R, Bacia, K, Briggs, J.A.G. | Deposit date: | 2013-07-26 | Release date: | 2013-09-18 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (40 Å) | Cite: | The Structure of the Copii Transport-Vesicle Coat Assembled on Membranes Elife, 2, 2013
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