PDB: 9760 resultsInfo pagesStatus searchChemie searchBIRD

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4NNO	Crystal Structure of Manganese ABC transporter substrate-binding protein MntC from Staphylococcus Aureus bound to a Zinc ion Descriptor: Lipoprotein, ZINC ION Authors: Rouge, L, Ahuja, S, Sudhamsu, J. Deposit date: 2013-11-18 Release date: 2014-11-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.174 Å) Cite: Structural analysis of bacterial ABC transporter inhibition by an antibody fragment. Structure, 23, 2015
6AXK	Crystal structure of Fab311 complex Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACE-ASN-PRO-ASN-ALA-ASN-PRO-ASN-ALA-ASN-PRO-ASN, Fab311 heavy chain, ... Authors: Oyen, D, Wilson, I.A. Deposit date: 2017-09-07 Release date: 2017-11-22 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.103 Å) Cite: Structural basis for antibody recognition of the NANP repeats in Plasmodium falciparum circumsporozoite protein. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
8U5B	Cryo-EM structure of human claudin-4 complex with Clostridium perfringens enterotoxin C-terminal domain and sFab COP-1 Descriptor: COP-1 sFab Heavy Chain, COP-1 sFab Light Chain, Claudin-4, ... Authors: Vecchio, A.J. Deposit date: 2023-09-12 Release date: 2023-09-27 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (5.3 Å) Cite: Structural and biophysical insights into targeting of claudin-4 by a synthetic antibody fragment. Commun Biol, 7, 2024
4NWU	Crystal structure of APE1551, an anti-human NGF Fab with a nine amino acid insertion in CDR H1 Descriptor: APE1551 Ab Fab heavy chain, APE1551 Ab Fab light chain Authors: Verdino, P, Stanfield, R.L, Wilson, I.A. Deposit date: 2013-12-06 Release date: 2014-10-22 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.602 Å) Cite: Nucleotide insertions and deletions complement point mutations to massively expand the diversity created by somatic hypermutation of antibodies. J.Biol.Chem., 289, 2014
8QH1	Crystal structure of the SARS-CoV-2 RBD from the Omicron BA4 variant with the antibody Cv2.3194 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cv2.3194 heavy chain, IGK@ protein, ... Authors: Fernandez, I, Rey, F.A. Deposit date: 2023-09-06 Release date: 2024-06-19 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Pan-neutralizing antibody isolated from a COVID patient To Be Published
8QH0	Crystal structure of the SARS-CoV-2 RBD with the antibody Cv2.3194 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cv2.3194 Heavy chain, GLYCEROL, ... Authors: Fernandez, I, Rey, F.A. Deposit date: 2023-09-06 Release date: 2024-06-19 Method: X-RAY DIFFRACTION (1.87 Å) Cite: A broadly neutralizing antibody against SARS-CoV-2 Omicron variants To Be Published
3NZH	Crystal structure of anti-emmprin antibody 5F6 FAB Descriptor: 5F6 HEAVY CHAIN, 5F6 LIGHT CHAIN, COBALT (II) ION, ... Authors: Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. Deposit date: 2010-07-16 Release date: 2011-07-27 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of anti-emmprin antibody 5F6 FAB To be Published
4NWT	Crystal structure of the anti-human NGF Fab APE1531 Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, APE1531 Ab Fab heavy chain, ... Authors: Verdino, P, Stanfield, R.L, Wilson, I.A. Deposit date: 2013-12-06 Release date: 2014-10-22 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Nucleotide insertions and deletions complement point mutations to massively expand the diversity created by somatic hypermutation of antibodies. J.Biol.Chem., 289, 2014
8U4V	Cryo-EM structure of human claudin-4 complex with Clostridium perfringens enterotoxin C-terminal domain, sFab COP-1, and Nanobody Descriptor: Anti-fab nanobody, COP-1 sFab Heavy Chain, COP-1 sFab Light Chain, ... Authors: Vecchio, A.J. Deposit date: 2023-09-11 Release date: 2023-10-25 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (2.99 Å) Cite: Structural and biophysical insights into targeting of claudin-4 by a synthetic antibody fragment. Commun Biol, 7, 2024
7SN0	Crystal structure of spike protein receptor binding domain of escape mutant SARS-CoV-2 from immunocompromised patient (d146*) in complex with human receptor ACE2 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Pan, J, Abraham, J, Clark, S. Deposit date: 2021-10-27 Release date: 2021-12-08 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.08 Å) Cite: Structural basis for continued antibody evasion by the SARS-CoV-2 receptor binding domain. Science, 375, 2022
6GKS	X-ray structure determined from recombinant Charcot-Leyden crystal Descriptor: GLYCEROL, Galectin-10 Authors: Verstraete, K, Verschueren, K, Savvides, S.N. Deposit date: 2018-05-21 Release date: 2019-06-05 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.38 Å) Cite: Protein crystallization promotes type 2 immunity and is reversible by antibody treatment. Science, 364, 2019
6GKQ	X-ray structure determined from ex vivo Charcot-Leyden crystal Descriptor: GLYCEROL, Galectin-10 Authors: Verstraete, K, Verschueren, K, Savvides, S.N. Deposit date: 2018-05-21 Release date: 2019-06-05 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Protein crystallization promotes type 2 immunity and is reversible by antibody treatment. Science, 364, 2019
6FGB	Human FcRn extra-cellular domain complexed with Fab fragment of Rozanolixizumab Descriptor: 1519.g57- Heavy chain, 1519.g57- Light chain, Beta-2-microglobulin, ... Authors: Sarkar, K, Ceska, T, Meier, C. Deposit date: 2018-01-10 Release date: 2018-08-29 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Generation and characterization of a high affinity anti-human FcRn antibody, rozanolixizumab, and the effects of different molecular formats on the reduction of plasma IgG concentration. MAbs, 10, 2018
7MLH	Crystal structure of human IgE (2F10) in complex with Der p 2.0103 Descriptor: CHLORIDE ION, Der p 2 variant 3, IgE Heavy chain, ... Authors: Khatri, K, Kapingidza, A.B, Richardson, C.M, Vailes, L.D, Wunschmann, S, Dolamore, C, Chapman, M.D, Smith, S.A, Pomes, A, Chruszcz, M. Deposit date: 2021-04-28 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Human IgE monoclonal antibody recognition of mite allergen Der p 2 defines structural basis of an epitope for IgE cross-linking and anaphylaxis in vivo. Pnas Nexus, 1, 2022
4KTD	Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, GE136, from non-human primate Descriptor: GE136 Heavy Chain Fab, GE136 Light Chain Fab, GLYCEROL, ... Authors: Poulsen, C, Tran, K, Standfield, R, Wyatt, R.T. Deposit date: 2013-05-20 Release date: 2014-02-05 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (2 Å) Cite: Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign. Proc.Natl.Acad.Sci.USA, 111, 2014
4KTE	Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, GE148, from non-human primate Descriptor: GE148 Heavy Chain Fab, GE148 Light Chain Fab, GLYCEROL, ... Authors: Poulsen, C, Tran, K, Stanfield, R, Wyatt, R.T. Deposit date: 2013-05-20 Release date: 2014-02-05 Last modified: 2019-12-25 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign. Proc.Natl.Acad.Sci.USA, 111, 2014
4OKV	Crystal structure of anopheline anti-platelet protein with Fab antibody Descriptor: Anti-platelet aggregation protein, heavy chain of 8H7 mAb, light chain of 8H7 mAb Authors: Park, S.Y, Sugiyama, K. Deposit date: 2014-01-23 Release date: 2014-04-30 Method: X-RAY DIFFRACTION (1.802 Å) Cite: The crystal structure of anopheles anti-platelet protein, a powerful anti-coagulant, in complex with an antibody To be Published
4R90	Anti CD70 Llama glama Fab 27B3 Descriptor: Anti CD70 Llama glama Fab 27B3 Heavy chain, Anti CD70 Llama glama Fab 27B3 Light chain, CALCIUM ION, ... Authors: Klarenbeek, A, El Mazouari, K, Desmyter, A, Blanchetot, C, Hultberg, A, Roovers, R.C, Cambillau, C, Spinelli, S, Del-Favero, J, Verrips, T, de Haard, H, Achour, I. Deposit date: 2014-09-03 Release date: 2015-06-24 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.746 Å) Cite: Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform. MAbs, 7, 2015
4R96	Structure of a Llama Glama Fab 48A2 against human cMet Descriptor: Llama glama Fab 48A2 against human cMet H chain, Llama glama Fab 48A2 against human cMet L chain Authors: Klarenbeek, A, El Mazouari, K, Desmyter, A, Blanchetot, C, Hultberg, A, Roovers, R.C, Cambillau, C, Spinelli, S, Del-Favero, J, Verrips, T, de Haard, H, Achour, I. Deposit date: 2014-09-03 Release date: 2015-06-24 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.31 Å) Cite: Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform. MAbs, 7, 2015
4HXB	Crystal structure of 6B9 FAB Descriptor: 6B9 FAB HEAVY CHAIN, 6B9 FAB LIGHT CHAIN, CALCIUM ION Authors: Johal, A.R, Jarrell, H.C, Khieu, N.H, Letts, J.A, Landry, R.C, Jachymek, W, Yang, Q, Jennings, H.J, Brisson, J.R, Evans, S.V. Deposit date: 2012-11-09 Release date: 2013-07-24 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.45 Å) Cite: The antigen-binding site of an N-propionylated polysialic acid-specific antibody protective against group B meningococci is consistent with extended epitopes. Glycobiology, 23, 2013
4HXA	Crystal structure of 13D9 FAB Descriptor: 13D9 FAB HEAVY CHAIN, 13D9 FAB LIGHT CHAIN Authors: Johal, A.R, Jarrell, H.C, Khieu, N.H, Letts, J.A, Landry, R.C, Jachymek, W, Yang, Q, Jennings, H.J, Brisson, J.R, Evans, S.V. Deposit date: 2012-11-09 Release date: 2013-07-24 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.06 Å) Cite: The antigen-binding site of an N-propionylated polysialic acid-specific antibody protective against group B meningococci is consistent with extended epitopes. Glycobiology, 23, 2013
8R1D	SD1-3 Fab in complex with SARS-CoV-2 BA.2.12.1 Spike Glycoprotein Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, SD1-3 Fab Heavy Chain, SD1-3 Fab Light Chain, ... Authors: Duyvesteyn, H.M.E, Ren, J, Stuart, D.I. Deposit date: 2023-11-01 Release date: 2024-03-13 Last modified: 2024-04-10 Method: ELECTRON MICROSCOPY (2.37 Å) Cite: The SARS-CoV-2 neutralizing antibody response to SD1 and its evasion by BA.2.86. Nat Commun, 15, 2024
6WHK	Minimally mutated anti-influenza broadly neutralizing antibody Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Fab Heavy Chain, ... Authors: Bajic, G, Schmidt, A.G. Deposit date: 2020-04-08 Release date: 2021-04-14 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Minimally mutated anti-influenza broadly neutralizing antibody To Be Published
6WJU	Fab Fragment of Anti-human LAG3 antibody (4A10) Descriptor: 4A10 Fab Heavy Chain, 4A10 Fab Light Chain Authors: Agnihotri, P, Mishra, A.K, Mariuzza, R.A. Deposit date: 2020-04-14 Release date: 2021-04-21 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Fab Fragment of Anti-human LAG3 antibody To Be Published
6WK4	Fab Fragment of Anti-human LAG3 antibody (13E2) Descriptor: 13E2 Fab Heavy Chain, 13E2 Fab Light Chain, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL Authors: Agnihotri, P, Mishra, A.K, Mariuzza, R.A. Deposit date: 2020-04-15 Release date: 2021-04-21 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Fab Fragment of Anti-human LAG3 antibody To Be Published

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