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5UPL
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BU of 5upl by Molmil
CDC42 binds PAK4 via an extended GTPase-effector inteface - 2 peptide: PAK4FL, CDC42 - UNREFINED
Descriptor: Cell division control protein 42 homolog, Serine/threonine-protein kinase PAK 4
Authors:Ha, B.H, Boggon, T.J.
Deposit date:2017-02-03
Release date:2017-12-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.003 Å)
Cite:CDC42 binds PAK4 via an extended GTPase-effector interface.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
2OS8
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BU of 2os8 by Molmil
Rigor-like structures of muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor
Descriptor: CALCIUM ION, MAGNESIUM ION, Myosin essential light chain, ...
Authors:Yang, Y, Gourinath, S, Cohen, C, Brown, J.H.
Deposit date:2007-02-05
Release date:2007-05-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.27 Å)
Cite:Rigor-like Structures from Muscle Myosins Reveal Key Mechanical Elements in the Transduction Pathways of This Allosteric Motor.
Structure, 15, 2007
5UPK
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BU of 5upk by Molmil
CDC42 binds PAK4 via an extended GTPase-effector interface - 3 peptide: PAK4cat, PAK4-N45, CDC42
Descriptor: Cell division control protein 42 homolog, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Ha, B.H, Boggon, T.J.
Deposit date:2017-02-03
Release date:2017-12-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:CDC42 binds PAK4 via an extended GTPase-effector interface.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3RM1
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BU of 3rm1 by Molmil
1.24 Angstrom X-ray structure of bovine TRTK12-Ca(2+)-S100B D63N
Descriptor: CALCIUM ION, F-actin-capping protein subunit alpha-2, Protein S100-B
Authors:Liriano, M.A, Weber, D.J.
Deposit date:2011-04-20
Release date:2012-04-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:The effects of CapZ peptide (TRTK12) on the protein dynamics of S100B and S100B D63N
To be Published
2RMK
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BU of 2rmk by Molmil
Rac1/PRK1 Complex
Descriptor: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Ras-related C3 botulinum toxin substrate 1, ...
Authors:Modha, R, Campbell, L.J, Nietlispach, D, Buhecha, H.R, Owen, D, Mott, H.R.
Deposit date:2007-10-25
Release date:2007-11-13
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:The Rac1 Polybasic Region Is Required for Interaction with Its Effector PRK1
J.Biol.Chem., 283, 2008
2JKG
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BU of 2jkg by Molmil
Plasmodium falciparum profilin
Descriptor: MAGNESIUM ION, OCTAPROLINE PEPTIDE, PROFILIN
Authors:Kursula, I, Kursula, P, Ganter, M, Panjikar, S, Matuschewski, K, Schueler, H.
Deposit date:2008-08-28
Release date:2008-09-23
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural Basis for Parasite-Specific Functions of the Divergent Profilin of Plasmodium Falciparum.
Structure, 16, 2008
2JKF
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BU of 2jkf by Molmil
Plasmodium falciparum profilin
Descriptor: PROFILIN
Authors:Kursula, I, Kursula, P, Ganter, M, Panjikar, S, Matuschewski, K, Schueler, H.
Deposit date:2008-08-28
Release date:2008-09-23
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structural Basis for Parasite-Specific Functions of the Divergent Profilin of Plasmodium Falciparum
Structure, 16, 2008
3KMW
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BU of 3kmw by Molmil
Crystal structure of the ILK/alpha-parvin core complex (MgATP)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Alpha-parvin, Integrin-linked kinase, ...
Authors:Fukuda, K, Qin, J.
Deposit date:2009-11-11
Release date:2009-12-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:The pseudoactive site of ILK is essential for its binding to alpha-Parvin and localization to focal adhesions.
Mol.Cell, 36, 2009
1QC6
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BU of 1qc6 by Molmil
EVH1 domain from ENA/VASP-like protein in complex with ACTA peptide
Descriptor: EVH1 DOMAIN FROM ENA/VASP-LIKE PROTEIN, PHE-GLU-PHE-PRO-PRO-PRO-PRO-THR-ASP-GLU-GLU
Authors:Fedorov, A.A, Fedorov, E.V, Gertler, F.B, Almo, S.C.
Deposit date:1999-05-17
Release date:1999-05-25
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of EVH1, a novel proline-rich ligand-binding module involved in cytoskeletal dynamics and neural function
Nat.Struct.Biol., 6, 1999
3KMU
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BU of 3kmu by Molmil
Crystal structure of the ILK/alpha-parvin core complex (apo)
Descriptor: Alpha-parvin, Integrin-linked kinase
Authors:Fukuda, K, Qin, J.
Deposit date:2009-11-11
Release date:2009-12-29
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The pseudoactive site of ILK is essential for its binding to alpha-Parvin and localization to focal adhesions.
Mol.Cell, 36, 2009
1QZP
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BU of 1qzp by Molmil
NMR structure of the human dematin headpiece domain
Descriptor: dematin
Authors:Frank, B.S, Vardar, D, Chishti, A.H, McKnight, C.J.
Deposit date:2003-09-17
Release date:2003-12-23
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The NMR structure of dematin headpiece reveals a dynamic loop that is conformationally altered upon phosphorylation at a distal site
J.Biol.Chem., 279, 2004
8T2M
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BU of 8t2m by Molmil
Crystal structure of GABARAP in complex with the LIR of NSs4
Descriptor: Non-structural protein S,Gamma-aminobutyric acid receptor-associated protein chimera
Authors:Ali, M.G.H, Wahba, H.M, Cyr, N, Omichinski, J.G.
Deposit date:2023-06-06
Release date:2024-04-03
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:An LIR motif in the Rift Valley fever virus NSs protein is critical for the interaction with LC3 family members and inhibition of autophagy.
Plos Pathog., 20, 2024
5FR1
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BU of 5fr1 by Molmil
Double acetylated RhoGDI-alpha in complex with RhoA-GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RHO GDP-DISSOCIATION INHIBITOR 1, ...
Authors:Kuhlmann, N, Wroblowski, S, Lammers, M.
Deposit date:2015-12-15
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Rhogdi Alpha Acetylation at K127 and K141 Affects Binding Towards Non-Prenylated Rhoa.
Biochemistry, 55, 2016
3IKU
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BU of 3iku by Molmil
Structural model of ParM filament in closed state from cryo-EM
Descriptor: Plasmid segregation protein parM
Authors:Galkin, V.E, Orlova, A, Rivera, C, Mullins, R.D, Egelman, E.H.
Deposit date:2009-08-06
Release date:2009-09-29
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (18 Å)
Cite:Structural polymorphism of the ParM filament and dynamic instability
Structure, 17, 2009
2EC6
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BU of 2ec6 by Molmil
Placopecten Striated Muscle Myosin II
Descriptor: CALCIUM ION, Myosin essential light chain, Myosin heavy chain, ...
Authors:Yang, Y, Brown, J, Samudrala, G, Reutzel, R, Szent-Gyorgyi, A.
Deposit date:2007-02-10
Release date:2008-02-26
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor.
Structure, 15, 2007
6WS0
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BU of 6ws0 by Molmil
Rational drug design of phenazopyridine derivatives as novel inhibitors of Rev1-CT
Descriptor: DNA polymerase zeta catalytic subunit, DNA repair protein REV1, Mitotic spindle assembly checkpoint protein MAD2B
Authors:McPherson, K.S, Korzhnev, D.M.
Deposit date:2020-04-30
Release date:2020-12-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Structure-Based Drug Design of Phenazopyridine Derivatives as Inhibitors of Rev1 Interactions in Translesion Synthesis.
Chemmedchem, 16, 2021
3OBV
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BU of 3obv by Molmil
Autoinhibited Formin mDia1 Structure
Descriptor: Protein diaphanous homolog 1, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose
Authors:Tomchick, D.R, Rosen, M.K, Otomo, T.
Deposit date:2010-08-09
Release date:2010-11-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structure of the Formin mDia1 in autoinhibited conformation.
Plos One, 5, 2010
6UXV
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BU of 6uxv by Molmil
SWI/SNF Body Module
Descriptor: SWI/SNF chromatin-remodeling complex subunit SNF5, SWI/SNF chromatin-remodeling complex subunit SWI1, SWI/SNF complex subunit SWI3, ...
Authors:He, Y, Han, Y.
Deposit date:2019-11-08
Release date:2020-03-18
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Cryo-EM structure of SWI/SNF complex bound to a nucleosome.
Nature, 579, 2020
2P2L
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BU of 2p2l by Molmil
Rac1-GDP-Zinc Complex
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Ras-related C3 botulinum toxin substrate 1, ZINC ION
Authors:Prehna, G, Stebbins, C.E.
Deposit date:2007-03-07
Release date:2007-05-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Rac1-GDP trimer complex binds zinc with tetrahedral and octahedral coordination, displacing magnesium.
Acta Crystallogr.,Sect.D, 63, 2007
6WS5
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BU of 6ws5 by Molmil
Rational drug design of phenazopyridine derivatives as novel inhibitors of Rev1-CT
Descriptor: 3-[(Z)-(2,3-difluorophenyl)diazenyl]pyridine-2,6-diamine, DNA polymerase zeta catalytic subunit, DNA repair protein REV1, ...
Authors:McPherson, K.S, Korzhnev, D.M.
Deposit date:2020-04-30
Release date:2020-12-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.472 Å)
Cite:Structure-Based Drug Design of Phenazopyridine Derivatives as Inhibitors of Rev1 Interactions in Translesion Synthesis.
Chemmedchem, 16, 2021
6VE5
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BU of 6ve5 by Molmil
X-ray structure of human REV7 in complex with Shieldin3 (residues 41-74)
Descriptor: Mitotic spindle assembly checkpoint protein MAD2B, SULFATE ION, Shieldin complex subunit 3
Authors:Cui, G, Botuyan, M.V, Mer, G.
Deposit date:2019-12-28
Release date:2021-01-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cryo-EM reveals conformational flexibility in apo DNA polymerase zeta.
J.Biol.Chem., 297, 2021
4ANJ
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BU of 4anj by Molmil
MYOSIN VI (MDinsert2-GFP fusion) PRE-POWERSTROKE STATE (MG.ADP.AlF4)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, CALMODULIN, ...
Authors:Menetrey, J, Isabet, T, Ropars, V, Mukherjea, M, Pylypenko, O, Liu, X, Perez, J, Vachette, P, Sweeney, H.L, Houdusse, A.M.
Deposit date:2012-03-19
Release date:2012-10-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Processive Steps in the Reverse Direction Require Uncoupling of the Lead Head Lever Arm of Myosin Vi.
Mol.Cell, 48, 2012
3PP5
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BU of 3pp5 by Molmil
High-resolution structure of the trimeric Scar/WAVE complex precursor Brk1
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Brk1, ...
Authors:Linkner, J, Witte, G, Curth, U, Faix, J.
Deposit date:2010-11-24
Release date:2011-06-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:High-resolution X-ray structure of the trimeric Scar/WAVE-complex precursor Brk1.
Plos One, 6, 2011
1RYU
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BU of 1ryu by Molmil
Solution Structure of the SWI1 ARID
Descriptor: SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1
Authors:Kim, S, Zhang, Z, Upchurch, S, Isern, N, Chen, Y.
Deposit date:2003-12-22
Release date:2004-05-25
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure and DNA-binding sites of the SWI1 AT-rich interaction domain (ARID) suggest determinants for sequence-specific DNA recognition.
J.Biol.Chem., 279, 2004
5LQW
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BU of 5lqw by Molmil
yeast activated spliceosome
Descriptor: Pre-mRNA leakage protein 1, Pre-mRNA-processing protein 45, Pre-mRNA-splicing factor 8, ...
Authors:Rauhut, R, Luehrmann, R.
Deposit date:2016-08-17
Release date:2016-10-05
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Molecular architecture of the Saccharomyces cerevisiae activated spliceosome
Science, 6306, 2016

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數據於2024-07-10公開中

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