8T2M

Crystal structure of GABARAP in complex with the LIR of NSs4

Summary for 8T2M

Entry DOI	10.2210/pdb8t2m/pdb
Descriptor	Non-structural protein S,Gamma-aminobutyric acid receptor-associated protein chimera (2 entities in total)
Functional Keywords	rift valley fever virus, autophagy, lc3, gabarap, lir, protein binding
Biological source	Homo sapiens (human) More
Total number of polymer chains	1
Total formula weight	15192.23
Authors	Ali, M.G.H.,Wahba, H.M.,Cyr, N.,Omichinski, J.G. (deposition date: 2023-06-06, release date: 2024-04-03)
Primary citation	Petraccione, K.,Ali, M.G.H.,Cyr, N.,Wahba, H.M.,Stocker, T.,Akhrymuk, M.,Akhrymuk, I.,Panny, L.,Bracci, N.,Cafaro, R.,Sastre, D.,Silberfarb, A.,O'Maille, P.,Omichinski, J.,Kehn-Hall, K. An LIR motif in the Rift Valley fever virus NSs protein is critical for the interaction with LC3 family members and inhibition of autophagy. Plos Pathog., 20:e1012093-e1012093, 2024 Cited by PubMed: 38512999 DOI: 10.1371/journal.ppat.1012093 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.27 Å)

Structure validation