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6QTY
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BU of 6qty by Molmil
Non-phosphorylated human CLK1 in complex with an indole inhibitor to 1.65 Ang
Descriptor: Dual specificity protein kinase CLK1, ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate
Authors:Livnah, O, Domovich, Y.
Deposit date:2019-02-26
Release date:2020-03-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Expression, purification and crystallization of CLK1 kinase - A potential target for antiviral therapy.
Protein Expr.Purif., 176, 2020
5WMJ
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BU of 5wmj by Molmil
KVWGSI segment from Superoxide Dismutase 1,residues 30-35
Descriptor: Superoxide dismutase [Cu-Zn], trifluoroacetic acid
Authors:Sangwan, S, Sawaya, M, Eisenberg, D.
Deposit date:2017-07-28
Release date:2018-03-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Atomic structures of corkscrew-forming segments of SOD1 reveal varied oligomer conformations.
Protein Sci., 27, 2018
1F09
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BU of 1f09 by Molmil
CRYSTAL STRUCTURE OF THE GREEN FLUORESCENT PROTEIN (GFP) VARIANT YFP-H148Q WITH TWO BOUND IODIDES
Descriptor: GREEN FLUORESCENT PROTEIN, IODIDE ION
Authors:Wachter, R.M, Yarbrough, D, Kallio, K, Remington, S.J.
Deposit date:2000-05-15
Release date:2000-11-17
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Crystallographic and energetic analysis of binding of selected anions to the yellow variants of green fluorescent protein.
J.Mol.Biol., 301, 2000
6QM7
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BU of 6qm7 by Molmil
Leishmania tarentolae proteasome 20S subunit complexed with GSK3494245
Descriptor: Proteasome alpha1 chain, Proteasome alpha2 chain, Proteasome alpha3 chain, ...
Authors:Rowland, P, Goswami, P.
Deposit date:2019-02-01
Release date:2019-04-17
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition.
Proc.Natl.Acad.Sci.USA, 116, 2019
2AWU
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BU of 2awu by Molmil
Synapse associated protein 97 PDZ2 domain variant C378G
Descriptor: AHH, Synapse-associated protein 97
Authors:Von Ossowski, I, Oksanen, E, Von Ossowski, L, Cai, C, Sundberg, M, Goldman, A, Keinanen, K.
Deposit date:2005-09-02
Release date:2006-08-29
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Crystal structure of the second PDZ domain of SAP97 in complex with a GluR-A C-terminal peptide
Febs J., 273, 2006
1F0B
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BU of 1f0b by Molmil
CRYSTAL STRUCTURE OF THE GREEN FLUORESCENT PROTEIN (GFP) VARIANT YFP-H148Q
Descriptor: GREEN FLUORESCENT PROTEIN
Authors:Wachter, R.M, Yarbrough, D, Kallio, K, Remington, S.J.
Deposit date:2000-05-15
Release date:2000-11-17
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystallographic and energetic analysis of binding of selected anions to the yellow variants of green fluorescent protein.
J.Mol.Biol., 301, 2000
4VGC
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BU of 4vgc by Molmil
GAMMA-CHYMOTRYPSIN D-NAPHTHYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX
Descriptor: D-1-NAPHTHYL-2-ACETAMIDO-ETHANE BORONIC ACID, GAMMA CHYMOTRYPSIN, SULFATE ION
Authors:Stoll, V.S, Eger, B.T, Hynes, R.C, Martichonok, V, Jones, J.B, Pai, E.F.
Deposit date:1997-05-01
Release date:1997-11-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes.
Biochemistry, 37, 1998
4ZJM
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BU of 4zjm by Molmil
Crystal Structure of Mycobacterium tuberculosis LpqH (Rv3763)
Descriptor: CHLORIDE ION, GLYCEROL, Lipoprotein LpqH, ...
Authors:Arbing, M.A, Chan, S, Kuo, E, Harris, L.R, Zhou, T.T, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
Deposit date:2015-04-29
Release date:2015-05-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.851 Å)
Cite:Crystal Structure of Mycobacterium tuberculosis LpqH (Rv3763)
To Be Published
2M7Y
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BU of 2m7y by Molmil
The Mengovirus Leader protein
Descriptor: Leader peptide, ZINC ION
Authors:Cornilescu, C.C, Porter, F.W, Zhao, K.Q, Davis, V, Palmenberg, A.C, Markley, J.L.
Deposit date:2013-05-02
Release date:2013-10-23
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Full Length Mengovirus Leader
To be Published
4ZES
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BU of 4zes by Molmil
Blood dendritic cell antigen 2 (BDCA-2) complexed with methyl-mannoside
Descriptor: C-type lectin domain family 4 member C, CALCIUM ION, MAGNESIUM ION, ...
Authors:Jegouzo, S.A.F, Feinberg, H, Dungarwalla, T, Drickamer, K, Weis, W.I, Taylor, M.E.
Deposit date:2015-04-20
Release date:2015-05-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:A Novel Mechanism for Binding of Galactose-terminated Glycans by the C-type Carbohydrate Recognition Domain in Blood Dendritic Cell Antigen 2.
J.Biol.Chem., 290, 2015
4UC1
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BU of 4uc1 by Molmil
High resolution crystal structure of translocator protein 18kDa (TSPO) from Rhodobacter sphaeroides (A139T Mutant) in C2 space group
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-1-(hexadecanoyloxy)-3-hydroxypropan-2-yl (11Z)-octadec-11-enoate, METHOXY-ETHOXYL, ...
Authors:Li, F, Liu, J, Zheng, Y, Garavito, R.M, Ferguson-Miller, S.
Deposit date:2014-08-13
Release date:2015-02-04
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism.
Science, 347, 2015
7CEL
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BU of 7cel by Molmil
CBH1 (E217Q) IN COMPLEX WITH CELLOHEXAOSE AND CELLOBIOSE
Descriptor: 1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE I, 2-acetamido-2-deoxy-beta-D-glucopyranose, COBALT (II) ION, ...
Authors:Divne, C, Stahlberg, J, Jones, T.A.
Deposit date:1997-09-24
Release date:1997-12-24
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:High-resolution crystal structures reveal how a cellulose chain is bound in the 50 A long tunnel of cellobiohydrolase I from Trichoderma reesei.
J.Mol.Biol., 275, 1998
4UC3
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BU of 4uc3 by Molmil
Translocator protein 18 kDa (TSPO) from Rhodobacter sphaeroides wild type
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate, TRANSLOCATOR PROTEIN TSPO
Authors:Li, F, Liu, J, Zheng, Y, Garavito, R.M, Ferguson-Miller, S.
Deposit date:2014-08-13
Release date:2015-02-04
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism.
Science, 347, 2015
2MMK
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BU of 2mmk by Molmil
Y41 and T47 phosphorylation of the Mengovirus Leader Protein: NMR Studies of the Phosphorylation of the Mengovirus Leader Protein Reveal Stabilization of Intermolecular Domain Interactions
Descriptor: Leader protein, ZINC ION
Authors:Bacot-Davis, V.R, Porter, F.W, Palmenberg, A.C.
Deposit date:2014-03-15
Release date:2014-10-15
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution structures of Mengovirus Leader protein, its phosphorylated derivatives, and in complex with nuclear transport regulatory protein, RanGTPase.
Proc.Natl.Acad.Sci.USA, 111, 2014
6DIX
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BU of 6dix by Molmil
NFVFGT segment from Human Immunoglobulin Light-Chain Variable Domain, Residues 98-103, assembled as an amyloid fibril
Descriptor: NFVFGT Immunoglobulin Light-Chain Variable Domain
Authors:Brumshtein, B, Esswein, S.R, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2018-05-23
Release date:2018-10-31
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1 Å)
Cite:Identification of two principal amyloid-driving segments in variable domains of Ig light chains in systemic light-chain amyloidosis.
J. Biol. Chem., 293, 2018
6D40
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BU of 6d40 by Molmil
Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma
Descriptor: Plasminogen, SULFATE ION, Trypsin inhibitor 1
Authors:Law, R.H.P, Wu, G.
Deposit date:2018-04-17
Release date:2019-01-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma.
J. Med. Chem., 62, 2019
6D3Y
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BU of 6d3y by Molmil
Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma
Descriptor: GLYCEROL, Plasminogen, SULFATE ION, ...
Authors:Law, R.H.P, Wu, G.
Deposit date:2018-04-17
Release date:2019-01-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma.
J. Med. Chem., 62, 2019
4UC2
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BU of 4uc2 by Molmil
Crystal structure of translocator protein 18kDa (TSPO) from rhodobacter sphaeroides (A139T mutant) in P212121 space group
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, TETRAETHYLENE GLYCOL, TRANSLOCATOR PROTEIN TSPO
Authors:Li, F, Liu, J, Zheng, Y, Garavito, R.M, Ferguson-Miller, S.
Deposit date:2014-08-13
Release date:2015-02-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism.
Science, 347, 2015
5A8F
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BU of 5a8f by Molmil
Structure and genome release mechanism of human cardiovirus Saffold virus-3
Descriptor: GENOME POLYPHUMAN SAFFOLD VIRUS-3 VP3 PROTEIN, HUMAN SAFFOLD VIRUS-3 VP1, HUMAN SAFFOLD VIRUS-3 VP2
Authors:Mullapudi, E, Novacek, J, Palkova, L, Kulich, P, Lindberg, M, vanKuppeveld, F.J.M, Plevka, P.
Deposit date:2015-07-15
Release date:2016-06-08
Last modified:2019-10-30
Method:ELECTRON MICROSCOPY (10.6 Å)
Cite:Structure and Genome Release Mechanism of Human Cardiovirus Saffold Virus-3.
J.Virol., 90, 2016
4B4I
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BU of 4b4i by Molmil
1.20 A Structure of Lysozyme Crystallized with (S)-2-methyl-2,4- pentanediol
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, LYSOZYME C
Authors:Jakoncic, J, Berger, J, Stauber, M, Axelbaum, A, Asherie, N.
Deposit date:2012-07-30
Release date:2012-08-22
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Crystallization of Lysozyme with (R)-, (S)- and (Rs)-2-Methyl-2,4-Pentanediol
Acta Crystallogr.,Sect.D, 71, 2015
2MXY
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BU of 2mxy by Molmil
Solution structure of hnRNP C RRM in complex with 5'-AUUUUUC-3' RNA
Descriptor: 5'-R(*AP*UP*UP*UP*UP*UP*C)-3', Heterogeneous nuclear ribonucleoproteins C1/C2
Authors:Cienikova, Z, Damberger, F.F, Hall, J, Allain, F.H.-T, Maris, C.
Deposit date:2015-01-19
Release date:2015-02-25
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural and mechanistic insights into poly(uridine) tract recognition by the hnRNP C RNA recognition motif.
J.Am.Chem.Soc., 136, 2014
2MZ1
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BU of 2mz1 by Molmil
Solution structure of hnRNP C RRM in complex with 5'-UUUUC-3' RNA
Descriptor: 5'-R(*UP*UP*UP*UP*C)-3', Heterogeneous nuclear ribonucleoproteins C1/C2
Authors:Cienikova, Z, Damberger, F.F, Hall, J, Allain, F.H.-T, Maris, C.
Deposit date:2015-02-05
Release date:2015-04-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural and mechanistic insights into poly(uridine) tract recognition by the hnRNP C RNA recognition motif.
J.Am.Chem.Soc., 136, 2014
6D3X
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BU of 6d3x by Molmil
Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma
Descriptor: Plasminogen, Trypsin inhibitor 1
Authors:Law, R.H.P, Wu, G.
Deposit date:2018-04-17
Release date:2019-01-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma.
J. Med. Chem., 62, 2019
6DIY
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BU of 6diy by Molmil
YTFGQ segment from Human Immunoglobulin Light-Chain Variable Domain, Residues 96-100, assembled as an amyloid fibril
Descriptor: YTFGQ segment Light-Chain Variable Domain Kappa AL09
Authors:Brumshtein, B, Esswein, S.R, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2018-05-24
Release date:2018-10-31
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (0.9 Å)
Cite:Identification of two principal amyloid-driving segments in variable domains of Ig light chains in systemic light-chain amyloidosis.
J. Biol. Chem., 293, 2018
2N1F
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BU of 2n1f by Molmil
Structure and assembly of the mouse ASC filament by combined NMR spectroscopy and cryo-electron microscopy
Descriptor: Apoptosis-associated speck-like protein
Authors:Sborgi, L, Ravotti, F, Dandey, V, Dick, M, Mazur, A, Reckel, S, Chami, M, Scherer, S, Bockmann, A, Egelman, E, Stahlberg, H, Broz, P, Meier, B, Hiller, S.
Deposit date:2015-04-01
Release date:2015-10-14
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4 Å), SOLID-STATE NMR
Cite:Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy.
Proc.Natl.Acad.Sci.USA, 112, 2015

223790

數據於2024-08-14公開中

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