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2N1F

Structure and assembly of the mouse ASC filament by combined NMR spectroscopy and cryo-electron microscopy

Summary for 2N1F
Entry DOI10.2210/pdb2n1f/pdb
EMDB information2971
NMR InformationBMRB: 26550
DescriptorApoptosis-associated speck-like protein (1 entity in total)
Functional Keywordsmouse asc filament, asc apoptosis-associated speck like protein containing a card, pyrin domain, inflammasomes, death domain, apoptosis
Biological sourceMus musculus (mouse)
Total number of polymer chains15
Total formula weight151780.26
Authors
Sborgi, L.,Ravotti, F.,Dandey, V.,Dick, M.,Mazur, A.,Reckel, S.,Chami, M.,Scherer, S.,Bockmann, A.,Egelman, E.,Stahlberg, H.,Broz, P.,Meier, B.,Hiller, S. (deposition date: 2015-04-01, release date: 2015-10-14, Last modification date: 2023-06-14)
Primary citationSborgi, L.,Ravotti, F.,Dandey, V.P.,Dick, M.S.,Mazur, A.,Reckel, S.,Chami, M.,Scherer, S.,Huber, M.,Bockmann, A.,Egelman, E.H.,Stahlberg, H.,Broz, P.,Meier, B.H.,Hiller, S.
Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy.
Proc.Natl.Acad.Sci.USA, 112:13237-13242, 2015
Cited by
PubMed: 26464513
DOI: 10.1073/pnas.1507579112
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (4 Å)
SOLID-STATE NMR (4 Å)
Structure validation

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