6DIX
NFVFGT segment from Human Immunoglobulin Light-Chain Variable Domain, Residues 98-103, assembled as an amyloid fibril
Summary for 6DIX
| Entry DOI | 10.2210/pdb6dix/pdb |
| Descriptor | NFVFGT Immunoglobulin Light-Chain Variable Domain (2 entities in total) |
| Functional Keywords | amyloid fibril, protein fibril |
| Biological source | Homo sapiens |
| Total number of polymer chains | 4 |
| Total formula weight | 2735.01 |
| Authors | Brumshtein, B.,Esswein, S.R.,Sawaya, M.R.,Eisenberg, D.S. (deposition date: 2018-05-23, release date: 2018-10-31, Last modification date: 2024-03-13) |
| Primary citation | Brumshtein, B.,Esswein, S.R.,Sawaya, M.R.,Rosenberg, G.,Ly, A.T.,Landau, M.,Eisenberg, D.S. Identification of two principal amyloid-driving segments in variable domains of Ig light chains in systemic light-chain amyloidosis. J. Biol. Chem., 293:19659-19671, 2018 Cited by PubMed: 30355736DOI: 10.1074/jbc.RA118.004142 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1 Å) |
Structure validation
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