6QTY
Non-phosphorylated human CLK1 in complex with an indole inhibitor to 1.65 Ang
Summary for 6QTY
Entry DOI | 10.2210/pdb6qty/pdb |
Related | 2VAG |
Descriptor | Dual specificity protein kinase CLK1, ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate (3 entities in total) |
Functional Keywords | clk1, splicing, kinase, viral infection, signaling protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 39787.54 |
Authors | Livnah, O.,Domovich, Y. (deposition date: 2019-02-26, release date: 2020-03-18, Last modification date: 2024-01-24) |
Primary citation | Dekel, N.,Eisenberg-Domovich, Y.,Karlas, A.,Meyer, T.F.,Bracher, F.,Lebendiker, M.,Danieli, T.,Livnah, O. Expression, purification and crystallization of CLK1 kinase - A potential target for antiviral therapy. Protein Expr.Purif., 176:105742-105742, 2020 Cited by PubMed: 32866611DOI: 10.1016/j.pep.2020.105742 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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