3ECN
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![BU of 3ecn by Molmil](/molmil-images/mine/3ecn) | Crystal structure of PDE8A catalytic domain in complex with IBMX | Descriptor: | 3-ISOBUTYL-1-METHYLXANTHINE, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A, MAGNESIUM ION, ... | Authors: | Wang, H, Yan, Z, Yang, S, Cai, J, Robinson, H, Ke, H. | Deposit date: | 2008-09-01 | Release date: | 2008-11-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Kinetic and structural studies of phosphodiesterase-8A and implication on the inhibitor selectivity Biochemistry, 47, 2008
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3EFX
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![BU of 3efx by Molmil](/molmil-images/mine/3efx) | Novel binding site identified in a hybrid between cholera toxin and heat-labile enterotoxin, 1.9A crystal structure reveals the details | Descriptor: | Cholera enterotoxin subunit B, Heat-labile enterotoxin B chain, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]beta-D-glucopyranose | Authors: | Holmner, A, Lebens, M, Teneberg, S, Angstrom, J, Okvist, M, Krengel, U. | Deposit date: | 2008-09-10 | Release date: | 2008-09-23 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Novel binding site identified in a hybrid between cholera toxin and heat-labile enterotoxin: 1.9 A crystal structure reveals the details Structure, 12, 2004
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3ECM
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![BU of 3ecm by Molmil](/molmil-images/mine/3ecm) | Crystal structure of the unliganded PDE8A catalytic domain | Descriptor: | High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A, MAGNESIUM ION, ZINC ION | Authors: | Wang, H, Yan, Z, Yang, S, Cai, J, Robinson, H, Ke, H. | Deposit date: | 2008-09-01 | Release date: | 2008-11-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Kinetic and structural studies of phosphodiesterase-8A and implication on the inhibitor selectivity Biochemistry, 47, 2008
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8Q5U
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![BU of 8q5u by Molmil](/molmil-images/mine/8q5u) | Endoglycosidase S2 in complex with IgG1 Fc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Sudol, A.S.L, Tews, I, Crispin, M. | Deposit date: | 2023-08-09 | Release date: | 2024-04-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The IgG-specific endoglycosidases EndoS and EndoS2 are distinguished by conformation and antibody recognition. J.Biol.Chem., 300, 2024
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4YT4
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![BU of 4yt4 by Molmil](/molmil-images/mine/4yt4) | |
1NXI
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![BU of 1nxi by Molmil](/molmil-images/mine/1nxi) | Solution structure of Vibrio cholerae protein VC0424 | Descriptor: | conserved hypothetical protein VC0424 | Authors: | Ramelot, T.A, Ni, S, Goldsmith-Fischman, S, Cort, J.R, Honig, B, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2003-02-10 | Release date: | 2003-07-01 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Solution structure of Vibrio cholerae protein VC0424: a variation of the ferredoxin-like fold. Protein Sci., 12, 2003
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3G10
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![BU of 3g10 by Molmil](/molmil-images/mine/3g10) | Structure of S. pombe Pop2p - Mg2+ and Mn2+ bound form | Descriptor: | CCR4-Not complex subunit Caf1, MAGNESIUM ION, MANGANESE (II) ION | Authors: | Andersen, K.R, Jonstrup, A.T, Van, L.B, Brodersen, D.E. | Deposit date: | 2009-01-29 | Release date: | 2009-03-31 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.597 Å) | Cite: | The activity and selectivity of fission yeast Pop2p are affected by a high affinity for Zn2+ and Mn2+ in the active site Rna, 15, 2009
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3G6W
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![BU of 3g6w by Molmil](/molmil-images/mine/3g6w) | |
3G0Z
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![BU of 3g0z by Molmil](/molmil-images/mine/3g0z) | Structure of S. pombe Pop2p - Zn2+ and Mn2+ bound form | Descriptor: | CCR4-Not complex subunit Caf1, MANGANESE (II) ION, ZINC ION | Authors: | Andersen, K.R, Jonstrup, A.T, Van, L.B, Brodersen, D.E. | Deposit date: | 2009-01-29 | Release date: | 2009-03-31 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.004 Å) | Cite: | The activity and selectivity of fission yeast Pop2p are affected by a high affinity for Zn2+ and Mn2+ in the active site Rna, 15, 2009
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1LV3
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![BU of 1lv3 by Molmil](/molmil-images/mine/1lv3) | Solution NMR Structure of Zinc Finger Protein yacG from Escherichia coli. Northeast Structural Genomics Consortium Target ET92. | Descriptor: | HYPOTHETICAL PROTEIN YacG, ZINC ION | Authors: | Ramelot, T.A, Cort, J.R, Yee, A.A, Semesi, A, Edwards, A.M, Arrowsmith, C.H, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2002-05-24 | Release date: | 2002-09-11 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | NMR structure of the Escherichia coli protein YacG: a novel sequence motif in the zinc-finger family of proteins. Proteins, 49, 2002
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3CU7
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![BU of 3cu7 by Molmil](/molmil-images/mine/3cu7) | Human Complement Component 5 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, ... | Authors: | Fredslund, F, Andersen, G.R. | Deposit date: | 2008-04-16 | Release date: | 2008-06-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.105 Å) | Cite: | Structure of and influence of a tick complement inhibitor on human complement component 5 Nat.Immunol., 9, 2008
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8PDP
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![BU of 8pdp by Molmil](/molmil-images/mine/8pdp) | 10-mer ring of HMPV N-RNA bound to the C-terminal region of P | Descriptor: | Nucleoprotein, Phosphoprotein, RNA | Authors: | Whitehead, J.D, Decool, H, Leyrat, C, Carrique, L, Fix, J, Eleouet, J.F, Galloux, M, Renner, M. | Deposit date: | 2023-06-12 | Release date: | 2023-12-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus. Nat Commun, 14, 2023
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8PDQ
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![BU of 8pdq by Molmil](/molmil-images/mine/8pdq) | 11-mer ring of HMPV N-RNA bound to the C-terminal region of P | Descriptor: | Nucleoprotein, Phosphoprotein, RNA | Authors: | Whitehead, J.D, Decool, H, Leyrat, C, Carrique, L, Fix, J, Eleouet, J.F, Galloux, M, Renner, M. | Deposit date: | 2023-06-12 | Release date: | 2023-12-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus. Nat Commun, 14, 2023
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8PDM
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![BU of 8pdm by Molmil](/molmil-images/mine/8pdm) | 11-mer ring of human metapneumovirus (HMPV) N-RNA | Descriptor: | Nucleoprotein, RNA | Authors: | Whitehead, J.D, Decool, H, Leyrat, C, Carrique, L, Fix, J, Eleouet, J.F, Galloux, M, Renner, M. | Deposit date: | 2023-06-12 | Release date: | 2023-12-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus. Nat Commun, 14, 2023
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8PDN
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![BU of 8pdn by Molmil](/molmil-images/mine/8pdn) | Spiral of assembled human metapneumovirus (HMPV) N-RNA | Descriptor: | Nucleoprotein, RNA | Authors: | Whitehead, J.D, Decool, H, Leyrat, C, Carrique, L, Fix, J, Eleouet, J.F, Galloux, M, Renner, M. | Deposit date: | 2023-06-12 | Release date: | 2023-12-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus. Nat Commun, 14, 2023
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8PDO
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![BU of 8pdo by Molmil](/molmil-images/mine/8pdo) | Local refinement of dimeric human metapneumovirus (HMPV) N-RNA | Descriptor: | Nucleoprotein, RNA | Authors: | Whitehead, J.D, Decool, H, Leyrat, C, Carrique, L, Fix, J, Eleouet, J.F, Galloux, M, Renner, M. | Deposit date: | 2023-06-12 | Release date: | 2023-12-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus. Nat Commun, 14, 2023
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8PDL
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![BU of 8pdl by Molmil](/molmil-images/mine/8pdl) | 10-mer ring of human metapneumovirus (HMPV) N-RNA | Descriptor: | Nucleoprotein, RNA | Authors: | Whitehead, J.D, Decool, H, Leyrat, C, Carrique, L, Fix, J, Eleouet, J.F, Galloux, M, Renner, M. | Deposit date: | 2023-06-12 | Release date: | 2023-12-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus. Nat Commun, 14, 2023
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8PDR
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![BU of 8pdr by Molmil](/molmil-images/mine/8pdr) | Rigid body fit of assembled HMPV N-RNA spiral bound to the C-terminal region of P | Descriptor: | Nucleoprotein, Phosphoprotein, RNA | Authors: | Whitehead, J.D, Decool, H, Leyrat, C, Carrique, L, Fix, J, Eleouet, J.F, Galloux, M, Renner, M. | Deposit date: | 2023-06-12 | Release date: | 2023-12-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus. Nat Commun, 14, 2023
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8PDS
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![BU of 8pds by Molmil](/molmil-images/mine/8pds) | Local refinement of dimeric HMPV N-RNA bound to the C-terminal region of P | Descriptor: | Nucleoprotein, Phosphoprotein, RNA | Authors: | Whitehead, J.D, Decool, H, Leyrat, C, Carrique, L, Fix, J, Eleouet, J.F, Galloux, M, Renner, M. | Deposit date: | 2023-06-12 | Release date: | 2023-12-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus. Nat Commun, 14, 2023
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3DTG
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![BU of 3dtg by Molmil](/molmil-images/mine/3dtg) | |
3FAT
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![BU of 3fat by Molmil](/molmil-images/mine/3fat) | X-ray structure of iGluR4 flip ligand-binding core (S1S2) in complex with (S)-AMPA at 1.90A resolution | Descriptor: | (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, ACETIC ACID, GLYCEROL, ... | Authors: | Kasper, C, Frydenvang, K, Naur, P, Gajhede, M, Kastrup, J.S. | Deposit date: | 2008-11-18 | Release date: | 2008-12-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4 Febs Lett., 582, 2008
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3GJC
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![BU of 3gjc by Molmil](/molmil-images/mine/3gjc) | Crystal Structure of the E290S mutant of LeuT with bound OG | Descriptor: | LEUCINE, SODIUM ION, Transporter, ... | Authors: | Winther, A.M.L, Quick, M, Javitch, J.A, Nissen, P. | Deposit date: | 2009-03-08 | Release date: | 2009-04-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Binding of an octylglucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation Proc.Natl.Acad.Sci.USA, 106, 2009
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3H6X
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![BU of 3h6x by Molmil](/molmil-images/mine/3h6x) | |
2Q2Z
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![BU of 2q2z by Molmil](/molmil-images/mine/2q2z) | Crystal Structure of KSP in Complex with Inhibitor 22 | Descriptor: | 1-[(4R)-4-[3-(4-ACETYLPIPERAZIN-1-YL)PROPYL]-1-(2-FLUORO-5-METHYLPHENYL)-4-PHENYL-4,5-DIHYDRO-1H-PYRAZOL-3-YL]ETHANONE, ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11, ... | Authors: | Yan, Y. | Deposit date: | 2007-05-29 | Release date: | 2007-09-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Kinesin spindle protein (KSP) inhibitors. Part 8: Design and synthesis of 1,4-diaryl-4,5-dihydropyrazoles as potent inhibitors of the mitotic kinesin KSP. Bioorg.Med.Chem.Lett., 17, 2007
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3FAS
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![BU of 3fas by Molmil](/molmil-images/mine/3fas) | X-ray structure of iGluR4 flip ligand-binding core (S1S2) in complex with (S)-glutamate at 1.40A resolution | Descriptor: | GLUTAMIC ACID, GLYCEROL, Glutamate receptor 4, ... | Authors: | Kasper, C, Frydenvang, K, Naur, P, Gajhede, M, Kastrup, J.S. | Deposit date: | 2008-11-18 | Release date: | 2008-12-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4 Febs Lett., 582, 2008
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