8T0Z
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![BU of 8t0z by Molmil](/molmil-images/mine/8t0z) | Human liver-type glutaminase (K253A) with L-Gln, filamentous form | Descriptor: | GLUTAMINE, Glutaminase liver isoform, mitochondrial | Authors: | Feng, S, Aplin, C, Nguyen, T.-T.T, Milano, S.K, Cerione, R.A. | Deposit date: | 2023-06-01 | Release date: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Filament formation drives catalysis by glutaminase enzymes important in cancer progression. Nat Commun, 15, 2024
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8T0Y
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![BU of 8t0y by Molmil](/molmil-images/mine/8t0y) | TRPV1 in nanodisc bound with one LPA in one monomer | Descriptor: | (2R)-2-hydroxy-3-(phosphonooxy)propyl tetradecanoate, (2R)-3-{[(R)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctadecanoate, SODIUM ION, ... | Authors: | Arnold, W.R, Cheng, Y. | Deposit date: | 2023-06-01 | Release date: | 2024-05-08 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of TRPV1 modulation by endogenous bioactive lipids. Nat.Struct.Mol.Biol., 2024
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8T0V
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![BU of 8t0v by Molmil](/molmil-images/mine/8t0v) | Closed state of lysine 5,6-aminomutase from Thermoanaerobacter tengcongensis | Descriptor: | 5'-DEOXYADENOSINE, COBALAMIN, D-lysine 5,6-aminomutase alpha subunit, ... | Authors: | Tian, S, Voss, P, Pham, K, Klose, T. | Deposit date: | 2023-06-01 | Release date: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Catalysis in Motion: Large-Scale Domain Shift Enables Co-C Bond Homolysis in Lysine 5,6-Aminomutase To Be Published
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8T0T
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![BU of 8t0t by Molmil](/molmil-images/mine/8t0t) | Structure of Compound 4 bound to human ALDH1A1 | Descriptor: | 1-(4-{6-fluoro-3-[4-(methanesulfonyl)piperazine-1-carbonyl]quinolin-4-yl}phenyl)cyclopropane-1-carbonitrile, Aldehyde dehydrogenase 1A1, CHLORIDE ION, ... | Authors: | Hurley, T.D. | Deposit date: | 2023-06-01 | Release date: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Development of substituted benzimidazoles as inhibitors of human aldehyde dehydrogenase 1A isoenzymes. Chem.Biol.Interact., 391, 2024
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8T0S
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![BU of 8t0s by Molmil](/molmil-images/mine/8t0s) | Crystal structure of UBE2G2 adduct with phenethyl isothiocyanate (PEITC) at the Cys48 position | Descriptor: | 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase AMFR, Ubiquitin-conjugating enzyme E2 G2 | Authors: | Wang, C, Shaw, G.X, Shi, G, Ji, X. | Deposit date: | 2023-06-01 | Release date: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of UBE2G2 adduct with phenethyl isothiocyanate (PEITC) at the Cys48 position To be published
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8T0R
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![BU of 8t0r by Molmil](/molmil-images/mine/8t0r) | |
8T0Q
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![BU of 8t0q by Molmil](/molmil-images/mine/8t0q) | Open state of lysine 5,6-aminomutase from Thermoanaerobacter tengcongensis | Descriptor: | 5'-DEOXYADENOSINE, COBALAMIN, D-lysine 5,6-aminomutase alpha subunit, ... | Authors: | Tian, S, Voss, P, Pham, K, Klose, T. | Deposit date: | 2023-06-01 | Release date: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | Catalysis in Motion: Large-Scale Domain Shift Enables Co-C Bond Homolysis in Lysine 5,6-Aminomutase To Be Published
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8T0P
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![BU of 8t0p by Molmil](/molmil-images/mine/8t0p) | Structure of Cse4 bound to Ame1 and Okp1 | Descriptor: | Histone H3-like centromeric protein CSE4, Inner kinetochore subunit AME1, Inner kinetochore subunit OKP1, ... | Authors: | Deng, S, Harrison, S.C. | Deposit date: | 2023-06-01 | Release date: | 2023-09-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Recognition of centromere-specific histone Cse4 by the inner kinetochore Okp1-Ame1 complex. Embo Rep., 24, 2023
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8T0O
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![BU of 8t0o by Molmil](/molmil-images/mine/8t0o) | Fab from mAb RB2AT_87 | Descriptor: | CHLORIDE ION, RB2AT_87 Fab Heavy chain, RB2AT_87 Fab Light chain | Authors: | Kreutzer, A.G, Malonis, R.J, Lai, J.R, Nowick, J.S. | Deposit date: | 2023-06-01 | Release date: | 2024-03-27 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Generation and Study of Antibodies against Two Triangular Trimers Derived from A beta. Pept Sci (Hoboken), 116, 2024
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8T0N
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![BU of 8t0n by Molmil](/molmil-images/mine/8t0n) | Structure of Compound 4 bound to human ALDH1A1 | Descriptor: | 2-methoxy-6-{[(1-propyl-1H-benzimidazol-2-yl)amino]methyl}phenol, Aldehyde dehydrogenase 1A1, CHLORIDE ION, ... | Authors: | Hurley, T.D. | Deposit date: | 2023-06-01 | Release date: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Development of substituted benzimidazoles as inhibitors of human aldehyde dehydrogenase 1A isoenzymes. Chem.Biol.Interact., 391, 2024
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8T0M
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![BU of 8t0m by Molmil](/molmil-images/mine/8t0m) | Proteasome 20S core particle from Pre1-1 Pre4-1 Double mutant | Descriptor: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | Authors: | Walsh Jr, R.M, Rawson, S, Schnell, H, Velez, B, Hanna, J. | Deposit date: | 2023-06-01 | Release date: | 2023-09-06 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Structure of the preholoproteasome reveals late steps in proteasome core particle biogenesis. Nat.Struct.Mol.Biol., 30, 2023
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8T0K
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![BU of 8t0k by Molmil](/molmil-images/mine/8t0k) | |
8T0J
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![BU of 8t0j by Molmil](/molmil-images/mine/8t0j) | Salmonella Typhimurium ArnD | Descriptor: | Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD | Authors: | Sousa, M.C, Munoz-Escudero, D, Lee, M. | Deposit date: | 2023-06-01 | Release date: | 2023-10-18 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Structure and Function of ArnD. A Deformylase Essential for Lipid A Modification with 4-Amino-4-deoxy-l-arabinose and Polymyxin Resistance. Biochemistry, 62, 2023
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8T0I
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![BU of 8t0i by Molmil](/molmil-images/mine/8t0i) | |
8T0H
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![BU of 8t0h by Molmil](/molmil-images/mine/8t0h) | |
8T0G
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![BU of 8t0g by Molmil](/molmil-images/mine/8t0g) | |
8T0E
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![BU of 8t0e by Molmil](/molmil-images/mine/8t0e) | TRPV1 in Nanodisc not bound with lysophosphatidic acid (apo) | Descriptor: | (2R)-3-{[(R)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctadecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1 | Authors: | Arnold, W.R, Cheng, Y. | Deposit date: | 2023-05-31 | Release date: | 2024-05-08 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis of TRPV1 modulation by endogenous bioactive lipids. Nat.Struct.Mol.Biol., 2024
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8T0D
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![BU of 8t0d by Molmil](/molmil-images/mine/8t0d) | |
8T0C
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![BU of 8t0c by Molmil](/molmil-images/mine/8t0c) | |
8T0B
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![BU of 8t0b by Molmil](/molmil-images/mine/8t0b) | |
8T09
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![BU of 8t09 by Molmil](/molmil-images/mine/8t09) | |
8T08
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![BU of 8t08 by Molmil](/molmil-images/mine/8t08) | Preholo-Proteasome from Pre1-1 Pre4-1 Double Mutant | Descriptor: | Proteasome assembly chaperone 2, Proteasome chaperone 1, Proteasome maturation factor UMP1, ... | Authors: | Walsh Jr, R.M, Rawson, S, Schnell, H, Velez, B, Hanna, J. | Deposit date: | 2023-05-31 | Release date: | 2023-09-06 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure of the preholoproteasome reveals late steps in proteasome core particle biogenesis. Nat.Struct.Mol.Biol., 30, 2023
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8T07
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![BU of 8t07 by Molmil](/molmil-images/mine/8t07) | Structure of mouse Myomaker mutant-Y118A bound to Fab18G7 | Descriptor: | 18G7 Fab heavy chain, 18G7 Fab light chain, Protein myomaker, ... | Authors: | Long, T, Li, X. | Deposit date: | 2023-05-31 | Release date: | 2023-09-27 | Last modified: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion. Nat.Struct.Mol.Biol., 30, 2023
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8T06
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![BU of 8t06 by Molmil](/molmil-images/mine/8t06) | Structure of mouse Myomaker mutant-R107A bound to Fab18G7 | Descriptor: | 18G7 Fab heavy chain, 18G7 Fab light chain, Protein myomaker, ... | Authors: | Long, T, Li, X. | Deposit date: | 2023-05-31 | Release date: | 2023-09-27 | Last modified: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (3.32 Å) | Cite: | Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion. Nat.Struct.Mol.Biol., 30, 2023
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8T05
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![BU of 8t05 by Molmil](/molmil-images/mine/8t05) | Structure of Ciona Myomaker bound to Fab1A1 | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 1A1 Fab heavy chain, 1A1 Fab light chain, ... | Authors: | Long, T, Li, X. | Deposit date: | 2023-05-31 | Release date: | 2023-09-27 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion. Nat.Struct.Mol.Biol., 30, 2023
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