8T0C
TRPV1 in Nanodisc bound with lysophosphatidic acid in all four monomers
Summary for 8T0C
| Entry DOI | 10.2210/pdb8t0c/pdb |
| EMDB information | 40940 |
| Descriptor | Transient receptor potential cation channel subfamily V member 1, (2R)-2-hydroxy-3-(phosphonooxy)propyl tetradecanoate, SODIUM ION (3 entities in total) |
| Functional Keywords | trpv1, lysophosphatidic acid, membrane protein |
| Biological source | Rattus norvegicus (Norway rat) |
| Total number of polymer chains | 4 |
| Total formula weight | 372192.38 |
| Authors | Arnold, W.R.,Cheng, Y. (deposition date: 2023-05-31, release date: 2024-05-08, Last modification date: 2024-05-15) |
| Primary citation | Arnold, W.R.,Mancino, A.,Moss 3rd, F.R.,Frost, A.,Julius, D.,Cheng, Y. Structural basis of TRPV1 modulation by endogenous bioactive lipids. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 38698206DOI: 10.1038/s41594-024-01299-2 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.5 Å) |
Structure validation
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