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6QD4	MloK1 model from single particle analysis of 2D crystals, class 8 (intermediate conformation) Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION Authors: Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H. Deposit date: 2018-12-31 Release date: 2019-04-24 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (5.6 Å) Cite: Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM. Nat Commun, 10, 2019
6WJG	PKA RIIbeta holoenzyme with DnaJB1-PKAc fusion in fibrolamellar hepatoceullar carcinoma Descriptor: DnaJ homolog subfamily B member 1, cAMP-dependent protein kinase catalytic subunit alpha fusion, cAMP-dependent protein kinase type II-beta regulatory subunit Authors: Lu, T.-W, Aoto, P.C, Weng, J.-H, Nielsen, C, Cash, J.N, Hall, J, Zhang, P, Simon, S.M, Cianfrocco, M.A, Taylor, S.S. Deposit date: 2020-04-13 Release date: 2020-12-02 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (6.2 Å) Cite: Structural analyses of the PKA RII beta holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma. Plos Biol., 18, 2020
6VY0	SthK P300A cyclic nucleotide-gated potassium channel in a putative active state, in complex with cAMP Descriptor: SthK Authors: Schmidpeter, P.A.M, Rheinberger, J, Nimigean, C.M. Deposit date: 2020-02-25 Release date: 2020-11-11 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (6.68 Å) Cite: Prolyl isomerization controls activation kinetics of a cyclic nucleotide-gated ion channel. Nat Commun, 11, 2020
4CHW	The electron crystallography structure of the cAMP-free potassium channel MloK1 Descriptor: CYCLIC NUCLEOTIDE-GATED POTASSIUM CHANNEL MLL3241, POTASSIUM ION Authors: Kowal, J, Chami, M, Baumgartner, P, Arheit, M, Chiu, P.L, Rangl, M, Scheuring, S, Schroeder, G.F, Nimigean, C.M, Stahlberg, H. Deposit date: 2013-12-04 Release date: 2014-01-15 Last modified: 2024-05-08 Method: ELECTRON CRYSTALLOGRAPHY (7 Å) Cite: Ligand-induced structural changes in the cyclic nucleotide-modulated potassium channel MloK1. Nat Commun, 5, 2014
4CHV	The electron crystallography structure of the cAMP-bound potassium channel MloK1 Descriptor: CYCLIC NUCLEOTIDE-GATED POTASSIUM CHANNEL MLL3241, POTASSIUM ION Authors: Kowal, J, Chami, M, Baumgartner, P, Arheit, M, Chiu, P.L, Rangl, M, Scheuring, S, Schroeder, G.F, Nimigean, C.M, Stahlberg, H. Deposit date: 2013-12-04 Release date: 2014-01-15 Last modified: 2024-05-08 Method: ELECTRON CRYSTALLOGRAPHY (7 Å) Cite: Ligand-Induced Structural Changes in the Cyclic Nucleotide-Modulated Potassium Channel Mlok1 Nat.Commun., 5, 2014
6WJF	PKA RIIbeta holoenzyme with DnaJB1-PKAc fusion in fibrolamellar hepatoceullar carcinoma Descriptor: DnaJ homolog subfamily B member 1,cAMP-dependent protein kinase catalytic subunit alpha fusion, cAMP-dependent protein kinase type II-beta regulatory subunit Authors: Lu, T.-W, Aoto, P.C, Weng, J.-H, Nielsen, C, Cash, J.N, Hall, J, Zhang, P, Simon, S.M, Cianfrocco, M.A, Taylor, S.S. Deposit date: 2020-04-13 Release date: 2020-12-02 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (7.5 Å) Cite: Structural analyses of the PKA RII beta holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma. Plos Biol., 18, 2020
3IYD	Three-dimensional EM structure of an intact activator-dependent transcription initiation complex Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, DNA (98-MER), ... Authors: Hudson, B.P, Quispe, J, Lara, S, Kim, Y, Berman, H, Arnold, E, Ebright, R.H, Lawson, C.L. Deposit date: 2009-08-01 Release date: 2009-11-10 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (19.799999 Å) Cite: Three-dimensional EM structure of an intact activator-dependent transcription initiation complex Proc.Natl.Acad.Sci.USA, 106, 2009
3J4Q	Pseudo-atomic model of the AKAP18-PKA complex in a bent conformation derived from electron microscopy Descriptor: A-kinase anchor protein 18, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type II-alpha regulatory subunit Authors: Reichow, S.L, Gonen, T. Deposit date: 2013-09-25 Release date: 2013-11-13 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (35 Å) Cite: Intrinsic disorder within an AKAP-protein kinase A complex guides local substrate phosphorylation. Elife, 2, 2013
3J4R	Pseudo-atomic model of the AKAP18-PKA Complex in a linear conformation derived from electron microscopy Descriptor: A-kinase anchor protein 18, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type II-alpha regulatory subunit Authors: Reichow, S.L, Gonen, T. Deposit date: 2013-09-25 Release date: 2013-11-13 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (35 Å) Cite: Intrinsic disorder within an AKAP-protein kinase A complex guides local substrate phosphorylation. Elife, 2, 2013
2KXL	Solution structure of a bacterial cyclic nucleotide-activated K+ channel binding domain in the unliganded state Descriptor: Cyclic nucleotide-gated potassium channel mll3241 Authors: Schunke, S, Stoldt, M, Willbold, D. Deposit date: 2010-05-10 Release date: 2011-04-20 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Structural insights into conformational changes of a cyclic nucleotide-binding domain in solution from Mesorhizobium loti K1 channel. Proc.Natl.Acad.Sci.USA, 108, 2011
2MHF	Solution structure of the cyclic-nucleotide binding homology domain of a KCNH channel Descriptor: Uncharacterized protein Authors: Li, Q, Ng, H. Deposit date: 2013-11-21 Release date: 2014-04-02 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Solution structure of the cyclic-nucleotide binding homology domain of a KCNH channel. J.Struct.Biol., 186, 2014
2MNG	Apo Structure of human HCN4 CNBD solved by NMR Descriptor: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Authors: Akimoto, M, Zhang, Z, Boulton, S, Selvaratnam, R, VanSchouwen, B, Gloyd, M, Accili, E.A, Lange, O.F, Melacini, G. Deposit date: 2014-04-03 Release date: 2014-06-04 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: A mechanism for the auto-inhibition of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel opening and its relief by cAMP. J.Biol.Chem., 289, 2014
2WC2	Nmr structure of catabolite activator protein in the unliganded state Descriptor: CATABOLITE GENE ACTIVATOR Authors: Popovych, N, Tzeng, S.R, Kalodimos, C.G. Deposit date: 2009-03-06 Release date: 2009-04-21 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Structural Basis for Camp-Mediated Allosteric Control of the Catabolite Activator Protein. Proc.Natl.Acad.Sci.USA, 106, 2009
4BHP	A structural model of CAP mutant (T127L and S128I) in cGMP-bound state Descriptor: CAMP RECEPTOR PROTEIN Authors: Tzeng, S.R, Kalodimos, C.G. Deposit date: 2013-04-04 Release date: 2013-05-08 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: Allosteric Inhibition Through Suppression of Transient Conformational States. Nat.Chem.Biol., 9, 2013
4BH9	A structural model of CAP mutant (T127L and S128I) in the apo state Descriptor: cAMP-activated global transcriptional regulator CRP Authors: Tzeng, S.R, Kalodimos, C.G. Deposit date: 2013-03-30 Release date: 2013-05-08 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: Allosteric inhibition through suppression of transient conformational states. Nat. Chem. Biol., 9, 2013
2K0G	Solution Structure of a Bacterial Cyclic Nucleotide-Activated K+ Channel Binding Domain in Complex with cAMP Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Mll3241 protein Authors: Schunke, S, Stoldt, M, Willbold, D. Deposit date: 2008-02-02 Release date: 2009-02-10 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution structure of the Mesorhizobium loti K1 channel cyclic nucleotide-binding domain in complex with cAMP. Embo Rep., 10, 2009
2MPF	Solution structure human HCN2 CNBD in the cAMP-unbound state Descriptor: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 Authors: Saponaro, A, Pauleta, S.R, Cantini, F, Matzapetakis, M, Hammann, C, Banci, L, Thiel, G, Santoro, B, Moroni, A. Deposit date: 2014-05-16 Release date: 2014-09-03 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function. Proc.Natl.Acad.Sci.USA, 111, 2014
2N7G	Structure of the cyclic nucleotide-binding homology domain of the hERG channel Descriptor: Potassium voltage-gated channel subfamily H member 2 Authors: Li, Y, Ng, H, Li, Q, Kang, C. Deposit date: 2015-09-10 Release date: 2016-05-18 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Structure of the Cyclic Nucleotide-Binding Homology Domain of the hERG Channel and Its Insight into Type 2 Long QT Syndrome Sci Rep, 6, 2016
2D93	Solution structure of the cNMP_binding domain of human Rap guanine nucleotide exchange factor 6 Descriptor: Rap guanine nucleotide exchange factor 6 Authors: Inoue, K, Muto, Y, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2005-12-08 Release date: 2006-06-08 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution structure of the cNMP_binding domain of human Rap guanine nucleotide exchange factor 6 to be published

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