PDB: 48088 resultsInfo pagesStatus searchChemie searchBIRD

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5LOX	Helical Assembly of the Anbu Complex from Pseudomonas aeruginosa Descriptor: Peptidase Authors: Fuchs, A.C.D, Albrecht, R, Martin, J, Hartmann, M.D. Deposit date: 2016-08-10 Release date: 2017-06-07 Last modified: 2017-06-14 Method: X-RAY DIFFRACTION (2.9 Å) Cite: The Architecture of the Anbu Complex Reflects an Evolutionary Intermediate at the Origin of the Proteasome System. Structure, 25, 2017
4YZT	Crystal structure of a tri-modular GH5 (subfamily 4) endo-beta-1, 4-glucanase from Bacillus licheniformis complexed with cellotetraose Descriptor: 1,2-ETHANEDIOL, Cellulose hydrolase, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose Authors: Liberato, M.V, Popov, A, Polikarpov, I. Deposit date: 2015-03-25 Release date: 2016-09-07 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.665 Å) Cite: Molecular characterization of a family 5 glycoside hydrolase suggests an induced-fit enzymatic mechanism. Sci Rep, 6, 2016
5LS7	Complex of wild type E. coli alpha aspartate decarboxylase with its processing factor PanZ Descriptor: ACETYL COENZYME *A, Aspartate 1-decarboxylase, CARBON DIOXIDE, ... Authors: Monteiro, D.C.F, Webb, M.E, Pearson, A.R. Deposit date: 2016-08-22 Release date: 2017-09-13 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.16 Å) Cite: The Mechanism of Regulation of Pantothenate Biosynthesis by the PanD-PanZAcCoA Complex Reveals an Additional Mode of Action for the Antimetabolite N-Pentyl Pantothenamide (N5-Pan). Biochemistry, 56, 2017
6WPK	SARM1 Autoinhibited Conformation Descriptor: NAD(+) hydrolase SARM1 Authors: Xie, T, Bratkowski, M, Bai, X, Sambashivan, S. Deposit date: 2020-04-27 Release date: 2020-08-12 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural and Mechanistic Regulation of the Prodegenerative NAD Hydrolase SARM1 Cell Rep, 32, 2020
8TH9	Structure of mammalian NEIL2 from Monodelphis domestica in complex with THF-containing DNA Descriptor: DIMETHYL SULFOXIDE, DNA (5'-D(*GP*CP*GP*TP*CP*CP*AP*(3DR)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*G)-3'), ... Authors: Eckenroth, B.E, Doublie, S. Deposit date: 2023-07-14 Release date: 2023-11-01 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.08 Å) Cite: Structural and biochemical insights into NEIL2's preference for abasic sites. Nucleic Acids Res., 51, 2023
4Z0B	Crystal Structure of the Fab Fragment of Anti-ofloxacin Antibody and Exploration Its Receptor Binding Site Descriptor: PHOSPHATE ION, antibody heavy chain, antibody light chain Authors: He, K, Du, X, Sheng, W, Zhou, X, Wang, J, Wang, S. Deposit date: 2015-03-26 Release date: 2016-04-27 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Crystal Structure of the Fab Fragment of an Anti-ofloxacin Antibody and Exploration of Its Specific Binding. J.Agric.Food Chem., 64, 2016
4PZ5	Crystal structure of the second and third fibronectin F1 modules in complex with a fragment of BBK32 from Borrelia burgdorferi Descriptor: Fibronectin, Fibronectin-binding protein BBK32 Authors: Harris, G, Potts, J.R. Deposit date: 2014-03-28 Release date: 2014-07-02 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Borrelia burgdorferi Protein BBK32 Binds to Soluble Fibronectin via the N-terminal 70-kDa Region, Causing Fibronectin to Undergo Conformational Extension. J.Biol.Chem., 289, 2014
4PZD	Crystal structure of (S)-3-hydroxybutyryl-CoA dehydrogenase PaaH1 in complex with NAD+ Descriptor: 3-Hydroxyacyl-CoA dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Kim, J, Chang, J.H, Kim, K.J. Deposit date: 2014-03-29 Release date: 2015-02-11 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.61 Å) Cite: Crystal structure and biochemical properties of the (S)-3-hydroxybutyryl-CoA dehydrogenase PaaH1 from Ralstonia eutropha Biochem.Biophys.Res.Commun., 448, 2014
4ZCV	Structure of calcium-bound regulatory domain of the human ATP-Mg/Pi carrier in the P212121 form Descriptor: CALCIUM ION, Calcium-binding mitochondrial carrier protein SCaMC-1, GLYCEROL, ... Authors: Harborne, S.P.D, Ruprecht, J.J, Kunji, E.R.S. Deposit date: 2015-04-16 Release date: 2015-07-22 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Calcium-induced conformational changes in the regulatory domain of the human mitochondrial ATP-Mg/Pi carrier. Biochim.Biophys.Acta, 1847, 2015
5LOU	human NUDT22 Descriptor: Nucleoside diphosphate-linked moiety X motif 22, PHOSPHATE ION Authors: Carter, M, Stenmark, P. Deposit date: 2016-08-10 Release date: 2017-09-13 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Human NUDT22 Is a UDP-Glucose/Galactose Hydrolase Exhibiting a Unique Structural Fold. Structure, 26, 2018
8TT7	NMR Assignments and Structure for the Dimeric Kinesin Neck Domain Descriptor: Kinesin heavy chain isoform 5C Authors: Alexandrescu, A.T. Deposit date: 2023-08-12 Release date: 2023-11-01 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Solution NMR assignments and structure for the dimeric kinesin neck domain. Biomol.Nmr Assign., 17, 2023
2XBR	Raman crystallography of Hen White Egg Lysozyme - Low X-ray dose (0.2 MGy) Descriptor: CHLORIDE ION, LYSOZYME C Authors: Carpentier, P, Royant, A, Weik, M, Bourgeois, D. Deposit date: 2010-04-14 Release date: 2010-11-24 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.29 Å) Cite: Raman Assisted Crystallography Reveals a Mechanism of X-Ray Induced Reversible Disulfide Radical Formation Structure, 18, 2010
4GPR	Crystal structure of EhUbc5, a ubiquitin conjugating enzyme from Entamoeba histolytica Descriptor: COBALT (II) ION, Ubiquitin-conjugating enzyme family protein Authors: Bosch, D.E, Siderovski, D.P. Deposit date: 2012-08-21 Release date: 2012-12-12 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural Determinants of Ubiquitin Conjugation in Entamoeba histolytica. J.Biol.Chem., 288, 2013
8TAZ	Cryo-EM structure of mink variant Y453F trimeric spike protein bound to one mink ACE2 receptors Descriptor: Angiotensin-converting enzyme, Spike glycoprotein Authors: Ahn, H.M, Calderon, B, Fan, X, Gao, Y, Horgan, N, Liang, B. Deposit date: 2023-06-28 Release date: 2023-10-25 Method: ELECTRON MICROSCOPY (3.75 Å) Cite: Structural basis of the American mink ACE2 binding by Y453F trimeric spike glycoproteins of SARS-CoV-2. J Med Virol, 95, 2023
6WXU	CryoEM structure of mouse DUOX1-DUOXA1 complex in the dimer-of-dimer state Descriptor: 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIUNDECYL PHOSPHATIDYL CHOLINE, ... Authors: Sun, J. Deposit date: 2020-05-12 Release date: 2020-09-02 Last modified: 2024-10-30 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Structures of mouse DUOX1-DUOXA1 provide mechanistic insights into enzyme activation and regulation. Nat.Struct.Mol.Biol., 27, 2020
1MNB	BIV TAT PEPTIDE (RESIDUES 68-81), NMR, MINIMIZED AVERAGE STRUCTURE Descriptor: BIV TAR RNA, BIV TAT PEPTIDE Authors: Puglisi, J.D, Chen, L, Blanchard, S, Frankel, A.D. Deposit date: 1996-07-25 Release date: 1997-01-27 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Solution structure of a bovine immunodeficiency virus Tat-TAR peptide-RNA complex. Science, 270, 1995
8GU6	Structure of the SbCas7-11-crRNA-NTR-Csx29 complex Descriptor: CHAT domain protein, RAMP superfamily protein, RNA (33-MER), ... Authors: Yu, G, Wang, X, Deng, Z, Zhang, H. Deposit date: 2022-09-10 Release date: 2023-01-18 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Target RNA-guided protease activity in type III-E CRISPR-Cas system. Nucleic Acids Res., 50, 2022
4QBX	Human Aldose Reductase complexed with a ligand with an IDD structure ({5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid) at 0.98 A Descriptor: Aldose reductase, CITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... Authors: Rechlin, C, Heine, A, Klebe, G. Deposit date: 2014-05-09 Release date: 2015-07-22 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (0.98 Å) Cite: Aldose Reductase: How expensive is the opening of the specificity pocket? IDD ligands under investigation To be Published
8GQ5	Human SARM1 bounded with NMN and Nanobody-C6, double-layer structure Descriptor: NAD(+) hydrolase SARM1, Nanobody C6 Authors: Cai, Y, Zhang, H. Deposit date: 2022-08-29 Release date: 2023-01-18 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: A conformation-specific nanobody targeting the nicotinamide mononucleotide-activated state of SARM1. Nat Commun, 13, 2022
8TWE	Cryo-EM structure of the PP2A:B55-FAM122A complex, B55 body Descriptor: PPP2R1A-PPP2R2A-interacting phosphatase regulator 1, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ... Authors: Fuller, J.R, Padi, S.K.R, Peti, W, Page, R. Deposit date: 2023-08-21 Release date: 2023-11-01 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (2.55 Å) Cite: Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19. Nature, 625, 2024
8GQ0	Crystal structure of BRD4 bromodomain 1 (BD1) in complex with STL233497 Descriptor: Bromodomain-containing protein 4, FORMIC ACID, GLYCEROL, ... Authors: Park, T.H, Lee, B.I. Deposit date: 2022-08-27 Release date: 2023-01-18 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.44 Å) Cite: Crystal structure of [1,2,4]triazolo[4,3-b]pyridazine derivatives as BRD4 bromodomain inhibitors and structure-activity relationship study. Sci Rep, 13, 2023
4ZE6	Endothiapepsin in complex with fragment B39 Descriptor: 1,2-ETHANEDIOL, 7-aminoheptanoic acid, ACETATE ION, ... Authors: Huschmann, F.U, Linnik, J, Weiss, M.S, Mueller, U. Deposit date: 2015-04-20 Release date: 2016-05-04 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.17 Å) Cite: Structures of endothiapepsin-fragment complexes from crystallographic fragment screening using a novel, diverse and affordable 96-compound fragment library. Acta Crystallogr.,Sect.F, 72, 2016
1MDI	HIGH RESOLUTION SOLUTION NMR STRUCTURE OF MIXED DISULFIDE INTERMEDIATE BETWEEN MUTANT HUMAN THIOREDOXIN AND A 13 RESIDUE PEPTIDE COMPRISING ITS TARGET SITE IN HUMAN NFKB Descriptor: TARGET SITE IN HUMAN NFKB, THIOREDOXIN Authors: Clore, G.M, Qin, J, Gronenborn, A.M. Deposit date: 1995-02-27 Release date: 1995-06-03 Last modified: 2024-10-16 Method: SOLUTION NMR Cite: Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NF kappa B. Structure, 3, 1995
8G08	Cryo-EM structure of SQ31f-bound Mycobacterium smegmatis ATP synthase rotational state 1 (backbone model) Descriptor: 3-[4-(morpholin-4-yl)phenyl]-4-{[(pyridin-2-yl)methyl]amino}cyclobut-3-ene-1,2-dione, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... Authors: Courbon, G.M, Rubinstein, J.L. Deposit date: 2023-01-31 Release date: 2023-02-15 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Mechanism of mycobacterial ATP synthase inhibition by squaramides and second generation diarylquinolines. Embo J., 42, 2023
4Z32	Crystal Structure of the FERM-SH2 Domains of Jak2 Descriptor: Tyrosine-protein kinase JAK2 Authors: McNally, R, Eck, M.J. Deposit date: 2015-03-30 Release date: 2016-06-22 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.04 Å) Cite: Crystal Structure of the FERM-SH2 Module of Human Jak2. Plos One, 11, 2016

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