5LS7

Complex of wild type E. coli alpha aspartate decarboxylase with its processing factor PanZ

Summary for 5LS7

Entry DOI	10.2210/pdb5ls7/pdb
Descriptor	Aspartate 1-decarboxylase, methyl radical, PanD maturation factor, ... (11 entities in total)
Functional Keywords	protein derived cofactor, coenzyme a biosynthesis, protein complex, metabolic pathway regulation, lyase
Biological source	Escherichia coli K-12 More
Cellular location	Cytoplasm : P0A790 P0A790
Total number of polymer chains	3
Total formula weight	33047.23
Authors	Monteiro, D.C.F.,Webb, M.E.,Pearson, A.R. (deposition date: 2016-08-22, release date: 2017-09-13, Last modification date: 2024-01-17)
Primary citation	Arnott, Z.L.P.,Nozaki, S.,Monteiro, D.C.F.,Morgan, H.E.,Pearson, A.R.,Niki, H.,Webb, M.E. The Mechanism of Regulation of Pantothenate Biosynthesis by the PanD-PanZAcCoA Complex Reveals an Additional Mode of Action for the Antimetabolite N-Pentyl Pantothenamide (N5-Pan). Biochemistry, 56:4931-4939, 2017 Cited by PubMed: 28832133 DOI: 10.1021/acs.biochem.7b00509 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.16 Å)

Structure validation