4ZE6
Endothiapepsin in complex with fragment B39
Summary for 4ZE6
| Entry DOI | 10.2210/pdb4ze6/pdb |
| Related | 3PB5 3PBZ 3PCW 3PGI 3PI0 3PLD 3PLL 3PM4 3PMU 3PMY |
| Descriptor | Endothiapepsin, DIMETHYL SULFOXIDE, GLYCEROL, ... (7 entities in total) |
| Functional Keywords | fragment screening, aspartic protease inhibition, hydrolase |
| Biological source | Cryphonectria parasitica (Chesnut blight fungus) |
| Total number of polymer chains | 1 |
| Total formula weight | 35186.57 |
| Authors | Huschmann, F.U.,Linnik, J.,Weiss, M.S.,Mueller, U. (deposition date: 2015-04-20, release date: 2016-05-04, Last modification date: 2023-11-15) |
| Primary citation | Huschmann, F.U.,Linnik, J.,Sparta, K.,Uhlein, M.,Wang, X.,Metz, A.,Schiebel, J.,Heine, A.,Klebe, G.,Weiss, M.S.,Mueller, U. Structures of endothiapepsin-fragment complexes from crystallographic fragment screening using a novel, diverse and affordable 96-compound fragment library. Acta Crystallogr.,Sect.F, 72:346-355, 2016 Cited by PubMed: 27139825DOI: 10.1107/S2053230X16004623 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.17 Å) |
Structure validation
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