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8SB2
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BU of 8sb2 by Molmil
CryoEM structure of DH270.I2-CH848.10.17
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17.SOSIP gp120, CH848.10.17.SOSIP gp41, ...
Authors:Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
Deposit date:2023-04-02
Release date:2023-04-19
Last modified:2023-05-31
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
8SB5
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BU of 8sb5 by Molmil
CryoEM structure of DH270.I1.6-CH848.10.17
Descriptor: CH848.10.17.SOSIP gp120, CH848.10.17.SOSIP gp41, DH270.I1.6 variable heavy chain, ...
Authors:Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
Deposit date:2023-04-02
Release date:2023-04-19
Last modified:2023-05-31
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
8SXI
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BU of 8sxi by Molmil
CH505 Disulfide Stapled SOSIP Bound to b12 Fab
Descriptor: Envelope glycoprotein gp160, HIV-1 gp41, b12 Heavy Chain, ...
Authors:Henderson, R.
Deposit date:2023-05-22
Release date:2024-02-14
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Microsecond dynamics control the HIV-1 Envelope conformation.
Sci Adv, 10, 2024
8TTW
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BU of 8ttw by Molmil
Cryo-EM structure of BG505 SOSIP.664 HIV-1 Env trimer in complex with temsavir, 8ANC195, and 10-1074
Descriptor: 1-[4-(benzenecarbonyl)piperazin-1-yl]-2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]ethane-1,2-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Tolbert, W.D, Pozharski, E, Pazgier, M.
Deposit date:2023-08-15
Release date:2023-11-08
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir.
Nat Commun, 14, 2023
7KDE
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BU of 7kde by Molmil
BG505 SOSIP.664 in complex with the V3-targeting rhesus macaque antibody 1485 and human gp120-gp41 interface antibody 8ANC195
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-10-08
Release date:2020-10-28
Last modified:2020-11-04
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:A broadly neutralizing macaque monoclonal antibody against the HIV-1 V3-Glycan patch.
Elife, 9, 2020
8SW7
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BU of 8sw7 by Molmil
BG505 Boost2 SOSIP.664 in complex with NHP polyclonal antibody FP1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 Boost 2 gp120, BG505 Boost 2 gp41, ...
Authors:Pratap, P.P, Antansijevic, A, Ozorowski, G, Ward, A.B.
Deposit date:2023-05-17
Release date:2023-07-26
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:Focusing antibody responses to the fusion peptide in rhesus macaques.
Biorxiv, 2023
8TGO
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BU of 8tgo by Molmil
Crystal structure of the BG505 triple tandem trimer gp140 HIV-1 Env in complex with PGT124 and 35O22
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 scFv, ...
Authors:Xian, Y, Yuan, M, Wilson, I.A.
Deposit date:2023-07-12
Release date:2024-04-17
Method:X-RAY DIFFRACTION (5.75 Å)
Cite:Triple tandem trimer immunogens for HIV-1 and influenza nucleic acid-based vaccines.
Npj Vaccines, 9, 2024
8TNH
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BU of 8tnh by Molmil
Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing llama nanobody G36 targeting the CD4-binding site
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD4-binding site nanobody G36, ...
Authors:Zhou, T, Kwong, P.D, Xu, J.
Deposit date:2023-08-01
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing llama nanobody G36 targeting the CD4-binding site
To Be Published
8TNI
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BU of 8tni by Molmil
Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing bi-specific antibody CAP256L-R27 targeting the CD4-binding site and the V2-apex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 BG505 DS-SOSIP gp120, ...
Authors:Zhou, T, Morano, N.C, Roark, R.S, Kwong, P.D, Xu, J.
Deposit date:2023-08-01
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (3.61 Å)
Cite:Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing bi-specific antibody CAP256L-R27 targeting the CD4-binding site and the V2-apex
To Be Published
8TNG
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BU of 8tng by Molmil
Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing llama nanobody R27 targeting the CD4-binding site
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD4-binding site targeting nanobody R27, ...
Authors:Zhou, T, Kwong, P.D, Xu, J.
Deposit date:2023-08-01
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing llama nanobody R27 targeting the CD4-binding site
To Be Published
7L6O
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BU of 7l6o by Molmil
Cryo-EM structure of HIV-1 Env CH848.3.D0949.10.17chim.6R.DS.SOSIP.664
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 - gp120, ...
Authors:Manne, K, Edwards, R.J, Acharya, P.
Deposit date:2020-12-23
Release date:2021-04-14
Last modified:2021-06-09
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Cell, 184, 2021
7L7T
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BU of 7l7t by Molmil
BG505 SOSIP reconstructed from a designed nanoparticle, BG505 SOSIP-T33-31 (Component A)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.v5.2(7S) - gp120, ...
Authors:Antanasijevic, A, Cannac, F, Sewall, L.M, Ward, A.B.
Deposit date:2020-12-30
Release date:2021-08-04
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
7L8C
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BU of 7l8c by Molmil
BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-3 from animal Rh.33104 (Wk26 time point)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP MD39 - gp120, ...
Authors:Antanasijevic, A, Sewall, L.M, Perrett, H.R, Ward, A.B.
Deposit date:2020-12-31
Release date:2021-08-04
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
7L8Y
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BU of 7l8y by Molmil
BG505 SOSIP.v5.2 N241/N289 in complex with the polyclonal Fab pAbC-5 from animal Rh.33311 (Wk26 time point)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.v5.2 N241/N289 - gp120, ...
Authors:Antanasijevic, A, Sewall, L.M, Cannac, F, Ward, A.B.
Deposit date:2021-01-01
Release date:2021-08-04
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
7L7U
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BU of 7l7u by Molmil
BG505 SOSIP reconstructed from a designed nanoparticle, BG505 SOSIP-T33-31 (Component B)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.v5.2(7S) - gp120, ...
Authors:Antanasijevic, A, Froes Rocha, R, Sewall, L.M, Ward, A.B.
Deposit date:2020-12-30
Release date:2021-08-04
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
7L8D
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BU of 7l8d by Molmil
BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-4 from animal Rh.33104 (Wk26 time point)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP MD39 - gp120, ...
Authors:Antanasijevic, A, Sewall, L.M, Ward, A.B.
Deposit date:2020-12-31
Release date:2021-08-04
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
7L8Z
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BU of 7l8z by Molmil
BG505 SOSIP.v5.2 N241/N289 in complex with the polyclonal Fab pAbC-7 from animal Rh.33311 (Wk26 time point)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.v5.2 N241/N289 - gp120, ...
Authors:Antanasijevic, A, Sewall, L.M, Perrett, H.R, Ward, A.B.
Deposit date:2021-01-01
Release date:2021-08-04
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
7L8A
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BU of 7l8a by Molmil
BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-1 from animal Rh.33104 (Wk26 time point)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP MD39 - gp120, ...
Authors:Antanasijevic, A, Sewall, L.M, Torrents de la Pena, A, Ward, A.B.
Deposit date:2020-12-31
Release date:2021-08-04
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
7L8T
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BU of 7l8t by Molmil
BG505 SOSIP.v5.2 N241/N289 in complex with the polyclonal Fab pAbC-1 from animal Rh.33311 (Wk26 time point)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.v5.2 N241/N289 - gp120, ...
Authors:Antanasijevic, A, Sewall, L.M, Ward, A.B.
Deposit date:2020-12-31
Release date:2021-08-04
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
7L88
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BU of 7l88 by Molmil
BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-3 from animal Rh.32034 (Wk26 time point)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP MD39 - gp120, ...
Authors:Antanasijevic, A, Sewall, L.M, Cannac, F, Perrett, H.R, Ward, A.B.
Deposit date:2020-12-31
Release date:2021-08-04
Last modified:2021-12-01
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
7L8U
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BU of 7l8u by Molmil
BG505 SOSIP.v5.2 N241/N289 in complex with the polyclonal Fab pAbC-2 from animal Rh.33311 (Wk26 time point)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.v5.2 N241/N289 - gp120, ...
Authors:Antanasijevic, A, Sewall, L.M, Rantalainen, K, Ward, A.B.
Deposit date:2021-01-01
Release date:2021-08-04
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
7L8S
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BU of 7l8s by Molmil
BG505 SOSIP.v5.2(7S) in complex with the polyclonal Fab pAbC-4 from animal Rh.33172 (Wk38 time point)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.v5.2(7S) - gp120, ...
Authors:Antanasijevic, A, Sewall, L.M, Ward, A.B.
Deposit date:2020-12-31
Release date:2021-08-04
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
7L8B
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BU of 7l8b by Molmil
BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-2 from animal Rh.33104 (Wk26 time point)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP MD39 - gp120, ...
Authors:Antanasijevic, A, Sewall, L.M, Yang, Y.R, Perrett, H.R, Ward, A.B.
Deposit date:2020-12-31
Release date:2021-08-04
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
7L8G
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BU of 7l8g by Molmil
BG505 SOSIP.v5.2(7S) in complex with the polyclonal Fab pAbC-3 from animal Rh.33172 (Wk38 time point)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:Antanasijevic, A, Sewall, L.M, Rantalainen, K, Ward, A.B.
Deposit date:2020-12-31
Release date:2021-08-04
Last modified:2021-09-08
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
7L89
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BU of 7l89 by Molmil
BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-4 from animal Rh.32034 (Wk26 time point)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP MD39 - gp120, ...
Authors:Antanasijevic, A, Sewall, L.M, Rantalainen, K, Perrett, H.R, Ward, A.B.
Deposit date:2020-12-31
Release date:2021-08-04
Last modified:2021-12-01
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021

221051

數據於2024-06-12公開中

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