8B9A
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9GEF
| Experimental localization of metal-binding sites reveals the role of metal ions in the delafloxacin-stabilized Streptococcus pneumoniae topoisomerase IV DNA cleavage complex | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CHLORIDE ION, ... | Authors: | Wang, B, Najmudin, S, Pan, X.-S, Mykhaylyk, V, Orr, C, Wagner, A, Govada, L, Chayen, N.E, Fisher, L.M, Sanderson, M.R. | Deposit date: | 2024-08-08 | Release date: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.62 Å) | Cite: | Experimental localization of metal-binding sites reveals the role of metal ions in type II DNA topoisomerases. Proc.Natl.Acad.Sci.USA, 121, 2024
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9F6I
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9F6L
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1FOS
| TWO HUMAN C-FOS:C-JUN:DNA COMPLEXES | Descriptor: | C-JUN PROTO-ONCOGENE PROTEIN, DNA (5'-D(*AP*AP*TP*GP*GP*AP*TP*GP*AP*GP*TP*CP*AP*TP*AP*GP*GP*AP*GP*A)-3'), DNA (5'-D(*TP*TP*CP*TP*CP*CP*TP*AP*TP*GP*AP*CP*TP*CP*AP*TP*CP*CP*AP*T)-3'), ... | Authors: | Glover, J.N.M, Harrison, S.C. | Deposit date: | 1995-03-07 | Release date: | 1995-07-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Crystal structure of the heterodimeric bZIP transcription factor c-Fos-c-Jun bound to DNA. Nature, 373, 1995
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9BDY
| AT-centric NF-kappaB RelA binding DNA | Descriptor: | ACETATE ION, DNA (5'-D(*CP*GP*GP*AP*AP*TP*TP*TP*CP*CP*CP*G)-3'), DNA (5'-D(*CP*GP*GP*GP*AP*AP*AP*TP*TP*CP*CP*G)-3'), ... | Authors: | Biswas, T, Shahabi, S, Tsodikov, O.V, Ghosh, G. | Deposit date: | 2024-04-13 | Release date: | 2024-08-07 | Last modified: | 2024-08-21 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Transient interactions modulate the affinity of NF-kappa B transcription factors for DNA. Proc.Natl.Acad.Sci.USA, 121, 2024
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8VAR
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8VAL
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8VAQ
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3N4M
| E. coli RNA polymerase alpha subunit C-terminal domain in complex with CAP and DNA | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, DI(HYDROXYETHYL)ETHER, ... | Authors: | Lara-Gonzalez, S, Birktoft, J.J, Lawson, C.L. | Deposit date: | 2010-05-21 | Release date: | 2011-05-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.987 Å) | Cite: | The RNA Polymerase alpha Subunit Recognizes the DNA Shape of the Upstream Promoter Element. Biochemistry, 59, 2020
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9BE0
| GC-centric NF-kappaB RelA binding DNA | Descriptor: | ACETATE ION, DNA (5'-D(*CP*GP*GP*GP*AP*AP*GP*TP*TP*CP*CP*GP*CP*GP*GP*AP*AP*CP*TP*TP*CP*CP*CP*G)-3'), ZINC ION | Authors: | Biswas, T, Shahabi, S, Tsodikov, O.V, Ghosh, G. | Deposit date: | 2024-04-13 | Release date: | 2024-08-07 | Last modified: | 2024-08-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Transient interactions modulate the affinity of NF-kappa B transcription factors for DNA. Proc.Natl.Acad.Sci.USA, 121, 2024
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3M3Y
| RNA polymerase II elongation complex C | Descriptor: | DNA (28-MER), DNA (5'-D(*GP*TP*GP*GP*TP*TP*AP*TP*GP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Wang, D, Zhu, G, Huang, X, Lippard, S.J. | Deposit date: | 2010-03-10 | Release date: | 2010-05-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.18 Å) | Cite: | X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct. Proc.Natl.Acad.Sci.USA, 107, 2010
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3M4O
| RNA polymerase II elongation complex B | Descriptor: | DNA (28-MER), DNA (5'-D(P*GP*TP*GP*GP*TP*TP*AP*TP*GP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Wang, D, Zhu, G, Huang, X, Lippard, S.J. | Deposit date: | 2010-03-11 | Release date: | 2010-05-12 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (3.57 Å) | Cite: | X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct. Proc.Natl.Acad.Sci.USA, 107, 2010
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9BDZ
| TA-centric NF-kappaB RelA binding DNA | Descriptor: | ACETATE ION, ZINC ION, double-stranded DNA | Authors: | Biswas, T, Shahabi, S, Tsodikov, O.V, Wang, V, Ghosh, G. | Deposit date: | 2024-04-13 | Release date: | 2024-08-07 | Last modified: | 2024-08-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Transient interactions modulate the affinity of NF-kappa B transcription factors for DNA. Proc.Natl.Acad.Sci.USA, 121, 2024
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8YHA
| Type I-EHNH Cascade-ssDNA complex | Descriptor: | 61-nt crRNA, CRISPR system Cascade subunit CasC, CRISPR system Cascade subunit CasD, ... | Authors: | Li, Z. | Deposit date: | 2024-02-27 | Release date: | 2024-07-31 | Last modified: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Mechanisms for HNH-mediated target DNA cleavage in type I CRISPR-Cas systems. Mol.Cell, 84, 2024
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9BE1
| CG-centric NF-kappaB RelA binding DNA | Descriptor: | ACETATE ION, DNA (5'-D(*CP*GP*GP*GP*AP*AP*TP*TP*TP*CP*CP*GP*CP*GP*GP*AP*AP*AP*TP*TP*CP*CP*CP*G)-3'), ZINC ION | Authors: | Biswas, T, Shahabi, S, Tsodikov, O.V, Wang, V, Ghosh, G. | Deposit date: | 2024-04-13 | Release date: | 2024-08-07 | Last modified: | 2024-08-21 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Transient interactions modulate the affinity of NF-kappa B transcription factors for DNA. Proc.Natl.Acad.Sci.USA, 121, 2024
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9C6Q
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9BF5
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6HV9
| S. cerevisiae CMG-Pol epsilon-DNA | Descriptor: | Cell division control protein 45, DNA (5'-D(*GP*CP*AP*GP*CP*CP*AP*CP*GP*CP*TP*GP*GP*CP*CP*GP*TP*TP*TP*TP*A)-3'), DNA (5'-D(P*TP*AP*AP*AP*AP*CP*GP*GP*CP*CP*AP*GP*CP*GP*TP*GP*GP*CP*TP*GP*C)-3'), ... | Authors: | Abid Ali, F, Purkiss, A.G, Cheung, A, Costa, A. | Deposit date: | 2018-10-10 | Release date: | 2018-12-12 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (4.98 Å) | Cite: | Structure of DNA-CMG-Pol epsilon elucidates the roles of the non-catalytic polymerase modules in the eukaryotic replisome. Nat Commun, 9, 2018
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4KFC
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3E00
| Intact PPAR gamma - RXR alpha Nuclear Receptor Complex on DNA bound with GW9662, 9-cis Retinoic Acid and NCOA2 Peptide | Descriptor: | (9cis)-retinoic acid, 2-chloro-5-nitro-N-phenylbenzamide, DNA (5'-D(*DCP*DAP*DAP*DAP*DCP*DTP*DAP*DGP*DGP*DTP*DCP*DAP*DAP*DAP*DGP*DGP*DTP*DCP*DAP*DG)-3'), ... | Authors: | Chandra, V, Huang, P, Hamuro, Y, Raghuram, S, Wang, Y, Burris, T.P, Rastinejad, F. | Deposit date: | 2008-07-30 | Release date: | 2008-10-28 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA. Nature, 456, 2008
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3DZY
| Intact PPAR gamma - RXR alpha Nuclear Receptor Complex on DNA bound with Rosiglitazone, 9-cis Retinoic Acid and NCOA2 Peptide | Descriptor: | (9cis)-retinoic acid, 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), ... | Authors: | Chandra, V, Huang, P, Hamuro, Y, Raghuram, S, Wang, Y, Burris, T.P, Rastinejad, F. | Deposit date: | 2008-07-30 | Release date: | 2008-10-28 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA. Nature, 456, 2008
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4KNY
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3DZU
| Intact PPAR gamma - RXR alpha Nuclear Receptor Complex on DNA bound with BVT.13, 9-cis Retinoic Acid and NCOA2 Peptide | Descriptor: | (9cis)-retinoic acid, 2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID, DNA (5'-D(*DCP*DAP*DAP*DAP*DCP*DTP*DAP*DGP*DGP*DTP*DCP*DAP*DAP*DAP*DGP*DGP*DTP*DCP*DAP*DG)-3'), ... | Authors: | Chandra, V, Huang, P, Hamuro, Y, Raghuram, S, Wang, Y, Burris, T.P, Rastinejad, F. | Deposit date: | 2008-07-30 | Release date: | 2008-10-28 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA. Nature, 456, 2008
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5JLW
| AntpHD with 15bp DNA duplex R-monothioated at Cytidine-8 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*AP*AP*AP*GP*CP*(C7R)P*AP*TP*TP*AP*GP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), ... | Authors: | White, M.A, Zandarashvili, L, Iwahara, J, Nguyen, D. | Deposit date: | 2016-04-27 | Release date: | 2016-06-22 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.088 Å) | Cite: | Stereospecific Effects of Oxygen-to-Sulfur Substitution in DNA Phosphate on Ion Pair Dynamics and Protein-DNA Affinity. Chembiochem, 17, 2016
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