PDB: 13252 resultsInfo pagesStatus searchChemie searchBIRD

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5J1P	Lassa virus L protein cap-snatching endonuclease. Bound to two manganese ions Descriptor: MANGANESE (III) ION, RNA-directed RNA polymerase L Authors: Reguera, J, Cusack, S. Deposit date: 2016-03-29 Release date: 2016-06-29 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.36 Å) Cite: Comparative Structural and Functional Analysis of Bunyavirus and Arenavirus Cap-Snatching Endonucleases. Plos Pathog., 12, 2016
5IZE	Hantaan virus L protein cap-snatching endonuclease Descriptor: MANGANESE (III) ION, RNA-directed RNA polymerase L Authors: Reguera, J, Cusack, S. Deposit date: 2016-03-25 Release date: 2016-06-29 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Comparative Structural and Functional Analysis of Bunyavirus and Arenavirus Cap-Snatching Endonucleases. Plos Pathog., 12, 2016
3IYD	Three-dimensional EM structure of an intact activator-dependent transcription initiation complex Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, DNA (98-MER), ... Authors: Hudson, B.P, Quispe, J, Lara, S, Kim, Y, Berman, H, Arnold, E, Ebright, R.H, Lawson, C.L. Deposit date: 2009-08-01 Release date: 2009-11-10 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (19.799999 Å) Cite: Three-dimensional EM structure of an intact activator-dependent transcription initiation complex Proc.Natl.Acad.Sci.USA, 106, 2009
4WC1	Structure of tRNA-processing enzyme with CTP Descriptor: CYTIDINE-5'-TRIPHOSPHATE, Poly A polymerase Authors: Yamashita, S, Tomita, K. Deposit date: 2014-09-04 Release date: 2015-04-15 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Measurement of Acceptor-T Psi C Helix Length of tRNA for Terminal A76-Addition by A-Adding Enzyme. Structure, 23, 2015
7ABH	Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion) Descriptor: Cell division cycle 5-like protein, DNA/RNA-binding protein KIN17, MINX M3 pre-mRNA, ... Authors: Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. Deposit date: 2020-09-07 Release date: 2020-12-09 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
6P1H	Cryo-EM Structure of DNA Polymerase Delta Holoenzyme Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (30-MER), ... Authors: Jain, R, Rice, W, Aggarwal, A.K. Deposit date: 2019-05-19 Release date: 2019-10-02 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Cryo-EM structure and dynamics of eukaryotic DNA polymerase delta holoenzyme. Nat.Struct.Mol.Biol., 26, 2019
4FVM	Crystal structure of yeast DNA polymerase alpha Descriptor: DNA polymerase alpha catalytic subunit A Authors: Perera, R.L, Pellegrini, L. Deposit date: 2012-06-29 Release date: 2013-02-27 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Mechanism for priming DNA synthesis by yeast DNA Polymerase alpha eLife, 2, 2013
8D6J	Human Ago2 bound to miR122(21nt) with PIWI loop swapped to AtAgo10 sequence Descriptor: MAGNESIUM ION, Protein argonaute-2, RNA (5'-R(P*UP*GP*GP*AP*GP*UP*GP*UP*GP*AP*CP*AP*AP*UP*GP*GP*UP*GP*UP*UP*U)-3') Authors: Xiao, Y, MacRae, I. Deposit date: 2022-06-06 Release date: 2023-05-03 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.5 Å) Cite: A tiny loop in the Argonaute PIWI domain tunes small RNA seed strength. Embo Rep., 24, 2023
4XJN	Structure of the parainfluenza virus 5 nucleocapsid-RNA complex: an insight into paramyxovirus polymerase activity Descriptor: LEAD (II) ION, Nucleocapsid, RNA (78-MER) Authors: Alayyoubi, M, Leser, G.P, Kors, C.A, Lamb, R.A. Deposit date: 2015-01-08 Release date: 2015-03-18 Last modified: 2017-08-23 Method: X-RAY DIFFRACTION (3.11 Å) Cite: Structure of the paramyxovirus parainfluenza virus 5 nucleoprotein-RNA complex. Proc.Natl.Acad.Sci.USA, 112, 2015
7ELL	In situ structure of capping enzyme lambda2, penetration protein mu1 of mammalian reovirus capsid asymmetric unit. Descriptor: MYRISTIC ACID, Mu1, mRNA (guanine-N(7)-)-methyltransferase Authors: Zhou, Z.H, Pan, M. Deposit date: 2021-04-12 Release date: 2021-10-20 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Asymmetric reconstruction of mammalian reovirus reveals interactions among RNA, transcriptional factor mu2 and capsid proteins. Nat Commun, 12, 2021
7ABF	Human pre-Bact-1 spliceosome core structure Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... Authors: Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. Deposit date: 2020-09-07 Release date: 2020-12-09 Last modified: 2020-12-30 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
4EQK	Crystal structure of the cap-binding domain of polymerase basic protein 2 from influenza virus A/Hong Kong/1/68 (h3n2) with bound m7GTP Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, NITRATE ION, Polymerase basic protein 2 Authors: Meng, G, Liu, Y, Zheng, X. Deposit date: 2012-04-19 Release date: 2013-03-06 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structural and functional characterization of K339T substitution identified in the PB2 subunit cap-binding pocket of influenza A virus J.Biol.Chem., 288, 2013
3RTX	Crystal structure of mammalian capping enzyme (Mce1) and Pol II CTD complex Descriptor: GUANINE, RNA Polymerase II C-terminal domain, mRNA-capping enzyme Authors: Ghosh, A, Lima, C.D. Deposit date: 2011-05-04 Release date: 2011-06-29 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.81 Å) Cite: Structural insights to how mammalian capping enzyme reads the CTD code. Mol.Cell, 43, 2011
1HVU	HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE COMPLEXED WITH A 33-BASE NUCLEOTIDE RNA PSEUDOKNOT Descriptor: PROTEIN (HIV-1 REVERSE TRANSCRIPTASE), RNA (33 NUCLEOTIDE RNA PSEUDOKNOT) Authors: Jaeger, J, Restle, T, Steitz, T.A. Deposit date: 1998-06-30 Release date: 1999-01-13 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (4.75 Å) Cite: The structure of HIV-1 reverse transcriptase complexed with an RNA pseudoknot inhibitor. EMBO J., 17, 1998
7OWF	KlenTaq DNA polymerase in a ternary complex with primer/template and the fluorescent nucleotide analog BFdUTP Descriptor: DNA polymerase I, thermostable, GLYCEROL, ... Authors: Betz, K, Srivatsan, S.G. Deposit date: 2021-06-18 Release date: 2022-06-29 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (1.91 Å) Cite: Microenvironment-Sensitive Fluorescent Nucleotide Probes from Benzofuran, Benzothiophene, and Selenophene as Substrates for DNA Polymerases. J.Am.Chem.Soc., 144, 2022
1QHT	DNA POLYMERASE FROM THERMOCOCCUS SP. 9ON-7 ARCHAEON Descriptor: PROTEIN (DNA POLYMERASE) Authors: Park, H.-W, Rodriguez, A.C, Beese, L.S. Deposit date: 1999-05-26 Release date: 2000-05-26 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structure of a pol alpha family DNA polymerase from the hyperthermophilic archaeon Thermococcus sp. 9 degrees N-7. J.Mol.Biol., 299, 2000
7ENJ	Human Mediator (deletion of MED1-IDR) in a Tail-bent conformation (MED-B) Descriptor: Isoform 2 of Mediator of RNA polymerase II transcription subunit 8, Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, ... Authors: Yin, X, Li, J, Wu, Z, Liu, W, Xu, Y. Deposit date: 2021-04-17 Release date: 2021-05-19 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Structures of the human Mediator and Mediator-bound preinitiation complex. Science, 372, 2021
6ZOL	SARS-CoV-2-Nsp1-40S complex, focused on head Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S12, ... Authors: Schubert, K, Karousis, E.D, Jomaa, A, Scaiola, A, Echeverria, B, Gurzeler, L.-A, Leibundgut, M.L, Thiel, V, Muehlemann, O, Ban, N. Deposit date: 2020-07-07 Release date: 2020-07-22 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation. Nat.Struct.Mol.Biol., 27, 2020
7EMF	Human Mediator (deletion of MED1-IDR) in a Tail-extended conformation Descriptor: Isoform 2 of Mediator of RNA polymerase II transcription subunit 16, Isoform 2 of Mediator of RNA polymerase II transcription subunit 8, Mediator of RNA polymerase II transcription subunit 1, ... Authors: Yin, X, Li, J, Wu, Z, Liu, W, Xu, Y. Deposit date: 2021-04-13 Release date: 2021-05-05 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structures of the human Mediator and Mediator-bound preinitiation complex. Science, 372, 2021
1NJX	THYMINE-GUANINE MISMATCH AT THE POLYMERASE ACTIVE SITE Descriptor: DNA POLYMERASE I, DNA PRIMER STRAND, DNA TEMPLATE STRAND, ... Authors: Johnson, S.J, Beese, L.S. Deposit date: 2003-01-02 Release date: 2004-03-30 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Structures of mismatch replication errors observed in a DNA polymerase. Cell(Cambridge,Mass.), 116, 2004
1NJW	GUANINE-THYMINE MISMATCH AT THE POLYMERASE ACTIVE SITE Descriptor: DNA POLYMERASE I, DNA PRIMER STRAND, DNA TEMPLATE STRAND, ... Authors: Johnson, S.J, Beese, L.S. Deposit date: 2003-01-02 Release date: 2004-03-30 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structures of mismatch replication errors observed in a DNA polymerase. Cell(Cambridge,Mass.), 116, 2004
4ENF	Crystal structure of the cap-binding domain of polymerase basic protein 2 from influenza virus A/Puerto Rico/8/34(h1n1) Descriptor: 1,4-BUTANEDIOL, NITRATE ION, Polymerase basic protein 2 Authors: Meng, G, Liu, Y, Zheng, X. Deposit date: 2012-04-13 Release date: 2013-03-06 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.32 Å) Cite: Structural and functional characterization of K339T substitution identified in the PB2 subunit cap-binding pocket of influenza A virus J.Biol.Chem., 288, 2013
4FYD	Crystal structure of yeast DNA polymerase alpha bound to DNA/RNA and dGTP Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*TP*GP*AP*GP*CP*GP*TP*G*TP*GP*TP*AP*CP*CP*CP*CP*TP*GP*CP*CP*CP*GP*CP*CP*G)-3'), DNA polymerase alpha catalytic subunit A, ... Authors: Perera, R.L, Pellegrini, L. Deposit date: 2012-07-04 Release date: 2013-02-27 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Mechanism for priming DNA synthesis by yeast DNA Polymerase alpha eLife, 2, 2013
3P87	Structure of human PCNA bound to RNASEH2B PIP box peptide Descriptor: Proliferating cell nuclear antigen, Ribonuclease H2 subunit B Authors: Bubeck, D, Reijns, M.A, Graham, S.C, Astell, K.R, Jones, E.Y, Jackson, A.P. Deposit date: 2010-10-13 Release date: 2011-02-02 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.99 Å) Cite: PCNA directs type 2 RNase H activity on DNA replication and repair substrates. Nucleic Acids Res., 39, 2011
4WLW	CRYSTAL STRUCTURE OF THE AG(I) (ACTIVATOR) FORM OF E. COLI CUER, A COPPER EFFLUX REGULATOR, BOUND TO COPA PROMOTER DNA Descriptor: DNA NON-TEMPLATE STRAND (5-D(*DGP*DAP*DCP*DCP *DTP*DTP*DCP*DCP*DCP*DCP*DTP*DTP*DGP*DCP*DTP*DGP*DGP*DAP *DAP*DGP*DGP*DTP*DC)-3, DNA TEMPLATE STRAND (5-D(*DGP*DAP*DCP*DCP*DTP *DTP*DCP*DCP*DAP*DGP*DCP*DAP*DAP*DGP*DGP*DGP*DGP*DAP*DAP *DGP*DGP*DTP*DC)-3, HTH-type transcriptional regulator CueR, ... Authors: Philips, S.J, Canalizo-Hernandez, M, Mondragon, A, O'Halloran, T.V. Deposit date: 2014-10-08 Release date: 2015-09-02 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.8 Å) Cite: TRANSCRIPTION. Allosteric transcriptional regulation via changes in the overall topology of the core promoter. Science, 349, 2015

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