4OGX
| Crystal structure of Fab DX-2930 in complex with human plasma kallikrein at 2.4 Angstrom resolution | Descriptor: | DX-2930 HEAVY CHAIN, DX-2930 LIGHT CHAIN, Plasma kallikrein, ... | Authors: | Edwards, T.E, Clifton, M.C, Abendroth, J, Nixon, A, Ladner, R. | Deposit date: | 2014-01-16 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Inhibition of plasma kallikrein by a highly specific active site blocking antibody. J.Biol.Chem., 289, 2014
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4B7I
| Crystal Structure of Human IgG Fc Bearing Hybrid-type Glycans | Descriptor: | CHLORIDE ION, IG GAMMA-1 CHAIN C REGION, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Bowden, T.A, Baruah, K, Coles, C.H, Harvey, D.J, Song, B.D, Stuart, D.I, Aricescu, A.R, Scanlan, C.N, Jones, E.Y, Crispin, M. | Deposit date: | 2012-08-20 | Release date: | 2012-10-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Chemical and Structural Analysis of an Antibody Folding Intermediate Trapped During Glycan Biosynthesis. J.Am.Chem.Soc., 134, 2012
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2GHV
| Crystal structure of SARS spike protein receptor binding domain | Descriptor: | Spike glycoprotein | Authors: | Hwang, W.C, Lin, Y, Santelli, E, Sui, J, Jaroszewski, L, Stec, B, Farzan, M, Marasco, W.A, Liddington, R.C. | Deposit date: | 2006-03-27 | Release date: | 2006-09-19 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis of neutralization by a human anti-severe acute respiratory syndrome spike protein antibody, 80R. J.Biol.Chem., 281, 2006
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4OGY
| Crystal structure of Fab DX-2930 in complex with human plasma kallikrein at 2.1 Angstrom resolution | Descriptor: | 1,2-ETHANEDIOL, DX-2930 HEAVY CHAIN, DX-2930 LIGHT CHAIN, ... | Authors: | Edwards, T.E, Clifton, M.C, Abendroth, J, Nixon, A, Ladner, R. | Deposit date: | 2014-01-16 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Inhibition of plasma kallikrein by a highly specific active site blocking antibody. J.Biol.Chem., 289, 2014
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1RVF
| FAB COMPLEXED WITH INTACT HUMAN RHINOVIRUS | Descriptor: | FAB 17-IA, HUMAN RHINOVIRUS 14 COAT PROTEIN | Authors: | Smith, T.J. | Deposit date: | 1996-09-05 | Release date: | 1998-02-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Neutralizing antibody to human rhinovirus 14 penetrates the receptor-binding canyon. Nature, 383, 1996
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2YWY
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2YWZ
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6XRT
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3BE1
| Dual specific bH1 Fab in complex with the extracellular domain of HER2/ErbB-2 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab Fragment-Heavy Chain, ... | Authors: | Bostrom, J.M, Wiesmann, C, Appleton, B.A. | Deposit date: | 2007-11-15 | Release date: | 2008-11-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Variants of the antibody herceptin that interact with HER2 and VEGF at the antigen binding site Science, 323, 2009
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3BDY
| Dual specific bH1 Fab in complex with VEGF | Descriptor: | Fab Fragment -Heavy Chain, Fab Fragment -Light Chain, GLYCEROL, ... | Authors: | Bostrom, J.M, Wiesmann, C, Appleton, B.A. | Deposit date: | 2007-11-15 | Release date: | 2008-11-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Variants of the antibody herceptin that interact with HER2 and VEGF at the antigen binding site Science, 323, 2009
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4YR6
| Fab fragment of 5G6 in complex with epitope peptide | Descriptor: | ACE-LYS-LEU-ARG-GLY-VAL-LEU-GLN-GLY-HIS-LEU, GLYCEROL, heavy chain of 5G6, ... | Authors: | Tao, Y, Mo, X, Li, R. | Deposit date: | 2015-03-14 | Release date: | 2016-03-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Structural basis for the specific inhibition of glycoprotein Ib alpha shedding by an inhibitory antibody. Sci Rep, 6, 2016
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8VUZ
| L5A7 Fab bound to 28H6E11 anti-idiotype Fab | Descriptor: | 28H6E11 Fab Heavy Chain, 28H6E11 Fab Light Chain, L5A7 Fab Heavy Chain, ... | Authors: | Olia, A.S, Morano, N.C, Kwong, P.D. | Deposit date: | 2024-01-30 | Release date: | 2024-05-22 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.95 Å) | Cite: | Anti-idiotype isolation of a broad and potent influenza A virus-neutralizing human antibody. Front Immunol, 15, 2024
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8VUE
| L5A7 Fab bound to Indonesia2005 Hemagglutinin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ... | Authors: | Olia, A.S, Gorman, J, Kwong, P.D. | Deposit date: | 2024-01-29 | Release date: | 2024-05-22 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.59 Å) | Cite: | Anti-idiotype isolation of a broad and potent influenza A virus-neutralizing human antibody. Front Immunol, 15, 2024
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4UV6
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6UG9
| Complex of ch28/11 Fab and SSEA-4 (hexagonal form) | Descriptor: | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ch28/11 Fab heavy chain, ch28/11 Fab light chain | Authors: | Soliman, C, Ramsland, P.A. | Deposit date: | 2019-09-26 | Release date: | 2019-12-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.74 Å) | Cite: | The terminal sialic acid of stage-specific embryonic antigen-4 has a crucial role in binding to a cancer-targeting antibody. J.Biol.Chem., 295, 2020
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1MFA
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6UGA
| ch28/11 Fab (monoclinic form) | Descriptor: | ch28/11 Fab heavy chain, ch28/11 Fab light chain, methanesulfonic acid | Authors: | Soliman, C, Ramsland, P.A. | Deposit date: | 2019-09-26 | Release date: | 2019-12-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The terminal sialic acid of stage-specific embryonic antigen-4 has a crucial role in binding to a cancer-targeting antibody. J.Biol.Chem., 295, 2020
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6UG7
| Complex of ch28/11 Fab and SSEA-4 (tetragonal form) | Descriptor: | 1,2-ETHANEDIOL, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, SULFATE ION, ... | Authors: | Soliman, C, Ramsland, P.A. | Deposit date: | 2019-09-26 | Release date: | 2019-12-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | The terminal sialic acid of stage-specific embryonic antigen-4 has a crucial role in binding to a cancer-targeting antibody. J.Biol.Chem., 295, 2020
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6UG8
| Complex of ch28/11 Fab and SSEA-4 (monoclinic form) | Descriptor: | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ch28/11 Fab heavy chain, ch28/11 Fab light chain | Authors: | Soliman, C, Ramsland, P.A. | Deposit date: | 2019-09-26 | Release date: | 2019-12-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | The terminal sialic acid of stage-specific embryonic antigen-4 has a crucial role in binding to a cancer-targeting antibody. J.Biol.Chem., 295, 2020
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5FYL
| Crystal Structure at 3.7 A Resolution of Fully Glycosylated HIV-1 Clade A BG505 SOSIP.664 Prefusion Env Trimer in Complex with Broadly Neutralizing Antibodies PGT122 and 35O22 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 ANTIBODY FAB HEAVY CHAIN, ... | Authors: | Stewart-Jones, G.B.E, Zhou, T, Thomas, P.V, Kwong, P.D. | Deposit date: | 2016-03-08 | Release date: | 2016-04-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B and G Cell(Cambridge,Mass.), 165, 2016
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3U30
| Crystal structure of a linear-specific Ubiquitin fab bound to linear ubiquitin | Descriptor: | Heavy chain Fab, Light chain Fab, linear di-ubiquitin | Authors: | Matsumoto, M.L, Dong, K.C, Yu, C, Phu, L, Gao, X, Hannoush, R.N, Hymowitz, S.G, Kirkpatrick, D.S, Dixit, V.M, Kelley, R.F. | Deposit date: | 2011-10-04 | Release date: | 2012-01-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.428 Å) | Cite: | Engineering and structural characterization of a linear polyubiquitin-specific antibody. J.Mol.Biol., 418, 2012
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2B1A
| Crystal structure analysis of anti-HIV-1 V3 Fab 2219 in complex with UG1033 peptide | Descriptor: | Fab 2219, heavy chain, light chain, ... | Authors: | Stanfield, R.L, Gorny, M.K, Zolla-Pazner, S, Wilson, I.A. | Deposit date: | 2005-09-15 | Release date: | 2006-07-04 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.348 Å) | Cite: | Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity. J.Virol., 80, 2006
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2B1H
| Crystal structure analysis of anti-HIV-1 V3 Fab 2219 in complex with UG29 peptide | Descriptor: | Fab 2219, heavy chain, light chain, ... | Authors: | Stanfield, R.L, Gorny, M.K, Zolla-Pazner, S, Wilson, I.A. | Deposit date: | 2005-09-15 | Release date: | 2006-07-04 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity. J.Virol., 80, 2006
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4JDT
| Crystal structure of chimeric germ-line precursor of NIH45-46 Fab in complex with gp120 of 93TH057 HIV-1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ... | Authors: | Scharf, L, Diskin, R, Bjorkman, P.J. | Deposit date: | 2013-02-25 | Release date: | 2013-03-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.26 Å) | Cite: | Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody. Proc.Natl.Acad.Sci.USA, 110, 2013
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6S3T
| P46, an immunodominant surface protein from Mycoplasma hyopneumoniae | Descriptor: | 46 kDa surface antigen, Immunoglobulin heavy chain, Immunoglobulin light chain, ... | Authors: | Guasch, A, Gonzalez-Gonzalez, L, Fita, I. | Deposit date: | 2019-06-26 | Release date: | 2019-11-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structure of P46, an immunodominant surface protein from Mycoplasma hyopneumoniae: interaction with a monoclonal antibody. Acta Crystallogr D Struct Biol, 76, 2020
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